Randomized clinical trial of an Acceptance and Commitment Therapy telehealth intervention (‘REVITALIZE’) to reduce fatigue interference in women with advanced ovarian cancer on PARP inhibitors: study protocol

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This study protocol outlines a randomized controlled trial evaluating the REVITALIZE telehealth intervention, which utilizes Acceptance and Commitment Therapy to address fatigue in women with advanced ovarian cancer taking PARP inhibitors. The research involves 240 participants assigned to either the eight-session remote therapy or an education-enhanced usual care group, with outcomes measured through patient-reported fatigue interference and objective medication adherence data. This resource is primarily intended for clinicians and researchers interested in the design and methodology of trials targeting cancer treatment side effects.

ID
a266f769c1cc4950
Source org
PubMed Central
Author
Joanna J. Arch (University of Colorado Boulder), Hajime Uno (Dana-Farber Cancer Institute), Hanneke Poort (Radboud University Nijmegen), Elizabeth Slivjak (University of Colorado Boulder), Madeline Nealis (University of Colorado Boulder), H. Park (Dana-Farber Cancer Institute), Irene Wang (Dana-Farber Cancer Institute), Sarah R. Genung (University of Colorado Boulder), Angel M. Cronin (Dana-Farber Cancer Institute), David J. Andorsky (Rocky Mountain Cancer Centers), L.J. Havrilesky (Duke Medical Center), Richard T. Penson (Massachusetts General Hospital), Varvara Mazina (Massachusetts General Hospital), Page Widick (Beth Israel Deaconess Medical Center), Carolyn Lefkowits (University of Colorado Anschutz Medical Campus), Alexi A. Wright (Dana-Farber Cancer Institute)
Published
2026-04-02
OA status
gold
DOI
10.1186/s12885-026-15936-0
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:a266f769c1cc4950,
  title = {Randomized clinical trial of an Acceptance and Commitment Therapy telehealth intervention (‘REVITALIZE’) to reduce fatigue interference in women with advanced ovarian cancer on PARP inhibitors: study protocol},
  author = {Joanna J. Arch and Hajime Uno and Hanneke Poort and Elizabeth Slivjak and Madeline Nealis and H. Park and Irene Wang and Sarah R. Genung and Angel M. Cronin and David J. Andorsky and L.J. Havrilesky and Richard T. Penson and Varvara Mazina and Page Widick and Carolyn Lefkowits and Alexi A. Wright},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1186/s12885-026-15936-0},
  url = {https://doi.org/10.1186/s12885-026-15936-0}
}

RIS

TY  - JOUR
TI  - Randomized clinical trial of an Acceptance and Commitment Therapy telehealth intervention (‘REVITALIZE’) to reduce fatigue interference in women with advanced ovarian cancer on PARP inhibitors: study protocol
AU  - Arch, Joanna J.
AU  - Uno, Hajime
AU  - Poort, Hanneke
AU  - Slivjak, Elizabeth
AU  - Nealis, Madeline
AU  - Park, H.
AU  - Wang, Irene
AU  - Genung, Sarah R.
AU  - Cronin, Angel M.
AU  - Andorsky, David J.
AU  - Havrilesky, L.J.
AU  - Penson, Richard T.
AU  - Mazina, Varvara
AU  - Widick, Page
AU  - Lefkowits, Carolyn
AU  - Wright, Alexi A.
PY  - 2026
PB  - PubMed Central
DO  - 10.1186/s12885-026-15936-0
UR  - https://doi.org/10.1186/s12885-026-15936-0
ER  -

APA

Arch, J. J., Uno, H., Poort, H., Slivjak, E., Nealis, M., Park, H., Wang, I., Genung, S. R., Cronin, A. M., Andorsky, D. J., Havrilesky, L., Penson, R. T., Mazina, V., Widick, P., Lefkowits, C., & Wright, A. A. (2026). Randomized clinical trial of an Acceptance and Commitment Therapy telehealth intervention (‘REVITALIZE’) to reduce fatigue interference in women with advanced ovarian cancer on PARP inhibitors: study protocol. PubMed Central. https://doi.org/10.1186/s12885-026-15936-0

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