How the risk of suicide and non-suicidal self-injury is assessed, monitored and managed in randomised controlled trials of interventions for youth depression: a scoping review

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This scoping review analyzes 89 randomized controlled trials of interventions for youth depression to examine how researchers handle suicide and self-harm risk. It details the extent to which studies exclude high-risk participants, the methods used to monitor risk during the trial, and the protocols for managing identified risks. The resource is intended for researchers and clinicians interested in the methodological standards and safety procedures of clinical trials involving young people.

ID
c7c07a2f01734a1c
Source org
PubMed Central
Author
Felicity Hudson (King's College London), Chloe Read-Williams (King's College London), Grace Williamson (King's College London), Samantha Lobo (King's College London), Amelia Hardman (King's College London), Haleemah Patel (King's College London), Victoria Pile (King's College London)
Published
2026-04-01
OA status
gold
DOI
10.1136/bmjopen-2025-111993
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:c7c07a2f01734a1c,
  title = {How the risk of suicide and non-suicidal self-injury is assessed, monitored and managed in randomised controlled trials of interventions for youth depression: a scoping review},
  author = {Felicity Hudson and Chloe Read-Williams and Grace Williamson and Samantha Lobo and Amelia Hardman and Haleemah Patel and Victoria Pile},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1136/bmjopen-2025-111993},
  url = {https://doi.org/10.1136/bmjopen-2025-111993}
}

RIS

TY  - JOUR
TI  - How the risk of suicide and non-suicidal self-injury is assessed, monitored and managed in randomised controlled trials of interventions for youth depression: a scoping review
AU  - Hudson, Felicity
AU  - Read-Williams, Chloe
AU  - Williamson, Grace
AU  - Lobo, Samantha
AU  - Hardman, Amelia
AU  - Patel, Haleemah
AU  - Pile, Victoria
PY  - 2026
PB  - PubMed Central
DO  - 10.1136/bmjopen-2025-111993
UR  - https://doi.org/10.1136/bmjopen-2025-111993
ER  -

APA

Hudson, F., Read-Williams, C., Williamson, G., Lobo, S., Hardman, A., Patel, H., & Pile, V. (2026). How the risk of suicide and non-suicidal self-injury is assessed, monitored and managed in randomised controlled trials of interventions for youth depression: a scoping review. PubMed Central. https://doi.org/10.1136/bmjopen-2025-111993

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