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10 merged results for "TREM2"

Partial results: at least one source did not answer. Available results are shown rather than treating an upstream outage as zero matches.

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  1. TREM2 triggers microglial density and age-related neuronal loss

    Bettina Linnartz-Gerlach, Liviu-Gabriel Bodea, Christine Klaus, Aurélien Ginolhac · 2019 · Glia

    limited evidence Transparent signal score 43/100 · policy 1.0.0

    Found in zenodo · DOI 10.1002/glia.23563

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    • cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

  2. A reporter cell system for the triggering receptor expressed on myeloid cells 2 reveals differential effects of diseaseassociated variants on receptor signaling and activation by antibodies against the stalk region

    Melanie Ibach, Mona Mathews, Bettina Linnartz-Gerlach, Sandra Theil · 2020

    limited evidence Transparent signal score 43/100 · policy 1.0.0

    Found in zenodo · DOI 10.1002/glia.23953

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  3. Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis

    Pablo Garcia-Reitboeck, Alexandra Phillips, Thomas M. Piers, Claudio Villegas-Llerena · 2018 · Cell Reports

    limited evidence Transparent signal score 43/100 · policy 1.0.0

    Found in zenodo · DOI 10.1016/j.celrep.2018.07.094

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    • cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

  4. A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC-derived microglia

    Thomas M. Piers, Katharina Cosker, Anna Mallach, Gabriel Thomas Johnson · 2019 · The FASEB Journal

    limited evidence Transparent signal score 43/100 · policy 1.0.0

    Found in zenodo · DOI 10.1096/fj.201902447r

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    • cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

  5. The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans

    Xianyuan Xiang, Thomas M. Piers, Benedikt Wefers, Kaichuan Zhu · 2018 · Molecular Neurodegeneration

    limited evidence Transparent signal score 43/100 · policy 1.0.0

    Found in zenodo · DOI 10.1186/s13024-018-0280-6

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    • cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

  6. An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function

    Kai Schlepckow, Gernot Kleinberger, Akio Fukumori, Regina Feederle · 2017 · EMBO Molecular Medicine

    limited evidence Transparent signal score 43/100 · policy 1.0.0

    Found in zenodo · DOI 10.15252/emmm.201707672

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    • cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

  7. TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant

    Peter Thornton, Jean Sevalle, Michael J Deery, Graham Fraser · 2017 · EMBO Molecular Medicine

    limited evidence Transparent signal score 43/100 · policy 1.0.0

    Found in zenodo · DOI 10.15252/emmm.201707673

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    • cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

  8. Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region

    Kai Schlepckow, Kathryn M Monroe, Gernot Kleinberger, Ludovico Cantuti-Castelvetri · 2020 · EMBO Molecular Medicine

    limited evidence Transparent signal score 43/100 · policy 1.0.0

    Found in zenodo · DOI 10.15252/emmm.201911227

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    • cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

  9. TREM2: A Target Enabling Package

    A Szykowska, Y Chen, T Smith, C Preger · 2021

    limited evidence Transparent signal score 43/100 · policy 1.0.0

    Found in zenodo · DOI 10.5281/zenodo.5256633

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    • cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

  10. TREM2 regulates purinergic receptormediated calcium signaling and motility in human iPSC-derived microglia

    Amit Jairaman, Amanda McQuade, Alberto Granzotto, You Jung Kang · 2022 · eLife

    limited evidence Transparent signal score 43/100 · policy 1.0.0

    Found in zenodo · DOI 10.7554/elife.73021

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    • cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer