Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.

Paganoni S, Fournier CN, Macklin EA, Chibnik LB, Quintana M, Saville BR, Detry MA, Vestrucci M, Marion J, McGlothlin A, Ajroud-Driss S, Chase M, Pothier L, Harkey BA, Yu H, Sherman AV, Shefner JM, Hall M, Kittle G, Berry JD, Babu S, Andrews J, Dagostino D, Tustison E, Giacomelli E, Scirocco E, Alameda G, Locatelli E, Ho D, Quick A, Katz J, Heitzman D, Appel SH, Shroff S, Felice K, Maragakis NJ, Simmons Z, Miller TM, Olney N, Weiss MD, Goutman SA, Fernandes JA, Jawdat O, Owegi MA, Foster LA, Vu T, Ilieva H, Newman DS, Arcila-Londono X, Jackson CE, Ladha S, Heiman-Patterson T, Caress JB, Swenson A, Peltier A, Lewis R, Fee D, Elliott M, Bedlack R, Kasarskis EJ, Elman L, Rosenfeld J, Walk D, McIlduff C, Twydell P, Young E, Johnson K, Rezania K, Goyal NA, Cohen JA, Benatar M, Jones V, Glass J, Shah J, Beydoun SR, Wymer JP, Zilliox L, Nayar S, Pattee GL, Martinez-Thompson J, Harvey B, Patel S, Mahoney P, Duda PW, Cudkowicz ME, HEALEY ALS Platform Trial Study Group

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DOI: 10.1001/jamanetworkopen.2024.59058
Published: 2025 Feb 3
Container: JAMA network open
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1001/jamanetworkopen.2024.59058,
  title = {Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.},
  author = {Paganoni S and Fournier CN and Macklin EA and Chibnik LB and Quintana M and Saville BR and Detry MA and Vestrucci M and Marion J and McGlothlin A and Ajroud-Driss S and Chase M and Pothier L and Harkey BA and Yu H and Sherman AV and Shefner JM and Hall M and Kittle G and Berry JD and Babu S and Andrews J and Dagostino D and Tustison E and Giacomelli E and Scirocco E and Alameda G and Locatelli E and Ho D and Quick A and Katz J and Heitzman D and Appel SH and Shroff S and Felice K and Maragakis NJ and Simmons Z and Miller TM and Olney N and Weiss MD and Goutman SA and Fernandes JA and Jawdat O and Owegi MA and Foster LA and Vu T and Ilieva H and Newman DS and Arcila-Londono X and Jackson CE and Ladha S and Heiman-Patterson T and Caress JB and Swenson A and Peltier A and Lewis R and Fee D and Elliott M and Bedlack R and Kasarskis EJ and Elman L and Rosenfeld J and Walk D and McIlduff C and Twydell P and Young E and Johnson K and Rezania K and Goyal NA and Cohen JA and Benatar M and Jones V and Glass J and Shah J and Beydoun SR and Wymer JP and Zilliox L and Nayar S and Pattee GL and Martinez-Thompson J and Harvey B and Patel S and Mahoney P and Duda PW and Cudkowicz ME and HEALEY ALS Platform Trial Study Group},
  year = {2025},
  journal = {JAMA network open},
  doi = {10.1001/jamanetworkopen.2024.59058},
  url = {https://doi.org/10.1001/jamanetworkopen.2024.59058}
}

RIS

TY  - JOUR
TI  - Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.
AU  - Paganoni S
AU  - Fournier CN
AU  - Macklin EA
AU  - Chibnik LB
AU  - Quintana M
AU  - Saville BR
AU  - Detry MA
AU  - Vestrucci M
AU  - Marion J
AU  - McGlothlin A
AU  - Ajroud-Driss S
AU  - Chase M
AU  - Pothier L
AU  - Harkey BA
AU  - Yu H
AU  - Sherman AV
AU  - Shefner JM
AU  - Hall M
AU  - Kittle G
AU  - Berry JD
AU  - Babu S
AU  - Andrews J
AU  - Dagostino D
AU  - Tustison E
AU  - Giacomelli E
AU  - Scirocco E
AU  - Alameda G
AU  - Locatelli E
AU  - Ho D
AU  - Quick A
AU  - Katz J
AU  - Heitzman D
AU  - Appel SH
AU  - Shroff S
AU  - Felice K
AU  - Maragakis NJ
AU  - Simmons Z
AU  - Miller TM
AU  - Olney N
AU  - Weiss MD
AU  - Goutman SA
AU  - Fernandes JA
AU  - Jawdat O
AU  - Owegi MA
AU  - Foster LA
AU  - Vu T
AU  - Ilieva H
AU  - Newman DS
AU  - Arcila-Londono X
AU  - Jackson CE
AU  - Ladha S
AU  - Heiman-Patterson T
AU  - Caress JB
AU  - Swenson A
AU  - Peltier A
AU  - Lewis R
AU  - Fee D
AU  - Elliott M
AU  - Bedlack R
AU  - Kasarskis EJ
AU  - Elman L
AU  - Rosenfeld J
AU  - Walk D
AU  - McIlduff C
AU  - Twydell P
AU  - Young E
AU  - Johnson K
AU  - Rezania K
AU  - Goyal NA
AU  - Cohen JA
AU  - Benatar M
AU  - Jones V
AU  - Glass J
AU  - Shah J
AU  - Beydoun SR
AU  - Wymer JP
AU  - Zilliox L
AU  - Nayar S
AU  - Pattee GL
AU  - Martinez-Thompson J
AU  - Harvey B
AU  - Patel S
AU  - Mahoney P
AU  - Duda PW
AU  - Cudkowicz ME
AU  - HEALEY ALS Platform Trial Study Group
PY  - 2025
JO  - JAMA network open
DO  - 10.1001/jamanetworkopen.2024.59058
UR  - https://doi.org/10.1001/jamanetworkopen.2024.59058
ER  -

APA

S, P., CN, F., EA, M., LB, C., M, Q., BR, S., MA, D., M, V., J, M., A, M., S, A., M, C., L, P., BA, H., H, Y., AV, S., JM, S., M, H., G, K., JD, B., S, B., J, A., D, D., E, T., E, G., E, S., G, A., E, L., D, H., A, Q., J, K., D, H., SH, A., S, S., K, F., NJ, M., Z, S., TM, M., N, O., MD, W., SA, G., JA, F., O, J., MA, O., LA, F., T, V., H, I., DS, N., X, A., CE, J., S, L., T, H., JB, C., A, S., A, P., R, L., D, F., M, E., R, B., EJ, K., L, E., J, R., D, W., C, M., P, T., E, Y., K, J., K, R., NA, G., JA, C., M, B., V, J., J, G., J, S., SR, B., JP, W., L, Z., S, N., GL, P., J, M., B, H., S, P., P, M., PW, D., ME, C., & Group, H. A. P. T. S. (2025). Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.. JAMA network open. https://doi.org/10.1001/jamanetworkopen.2024.59058

Source records

pubmed · retrieved 2026-09-26T06:44:17.396Z