Restrictive vs Liberal Transfusion Strategy in Traumatic Brain Injury

Irene Sbaraini Zernini, Chiara Faso, Carla Bittencourt Rynkowski, Kirsten Moller, Piet Lormans, Manuel Quintana Diaz, Anselmo Caricato, Marjorie Beumier, Evy Voets, Mario Arias, Herve Quintard, Diego Morocho, Pedro Kurtz, Erik Roman Pognuz, Olivier Huet, Ata Mahmoodpoor, Aaron Blandino-Ortiz, Sara Alcantara, Russell Chabanne, Francisco Cicho, Stan Popugaev, Angelo Giacomucci, Jamil Dibu, Raphael Cinotti, Pierre Bouzat, Jean-Louis Vincent, Elisa Gouvêa Bogossian, Fabio Silvio Taccone, Unknown, Claudia Díaz, Andrés Saravia, Ahmas Bayrlee, Laura Nedolast, Hussam Elkambergy, Haamid Siddique, Jihad Mallat, Nahla AlJaberi, Samer Shoshan, Ayo Mandi, Bruno De Oliveira, Malligere Prasanna, Rehan Haque, Dnyaneshwar Munde, Sara Chaffee, Fatma Alawadhi, Jamil Dibu, Eija Junttila, Teemu Luoto, Simona Šteblaj, Jacques Creteur, Dominique Durand, Caroline Abbenhuijs, Nancy Itesa Matumikina, Filippo Annoni, Leda Nobile, Miguel Ulloa Bersatti, Igor Yovenko, Alexander Tsarev, Jasperina Dubois, Evy Voets, Luc Janssen, Luigi Zattera, Leire Pedrosa, Berta Monleon Lopez, Ainhoa Serrano, Nekane Romero-García, Xavier Wittebole, Antonio M Dell'Anna, Camilla Gelormini, Eleonora Stival, Pilar Marcos Neira, Regina Roig Pineda, Lara Bielsa Berrocal, Maite Misis del Campo, Stepani Bendel, Jorge H Mejía-Mantilla, Ángela Marulanda, Wojciech Dabrowski, Rune Damgaard Nielsen, Markus Harboe Olsen, Helene Ravnholt Jensen, Ida Møller Larsen, Roberta Tallarico, Umberto Lucangelo, Maria Isabel Gonzales Perez, Carole Ichai, Karim Asenhoune, Karim Lakhal, Charlotte Fernandez-Canal, Samuel Gay, Marie Lebouc, David Bougon, Etienne Escudier, Michel Sirodot, Albrice Levrat, Alix Courouau, Jacques Duranteau, Aurore Rodrigues, Naima Makouche, Gilles Francony, Olivier Vincent, Perrine Boucheix, Clotilde Schilte, Anais Adolle, Thomas Gargadennec, Patricia Dias, Gwenaelle Desanglois, Alexia Meheut, Pauline Cam, Geert Meyfroidt, Liese Mebis, Alexandra Hendrickx, Pieetr Wouters, Sylvia Van Hulle, Alain D'Hondt, Marjorie Beumier, Marc Burgeois, Olivier Simonet, Frederic Vallot, Pablo Centeno, Matias Anchorena, Ximena Benavente, Maximilian D'Onofrio, Nydia Funes, Antonio Barra de Oca, Gabriela Izzo, Charlotte Castelain, Filippo Soetens, Mario Arias, Diego Morocho, Manuel Jabaja, Diego Tutillo, Stan Popugaev, Celeste Dias, Elena Perez Solada, Pilar Justo, Amparo Lopez Gomez, Sara Alcantara, Francisco Chico, Maria Fernanda Garcia, Fabricio Picoita, Stela Velasco Eichler, Gabriela Nonticuri Bianchi, João Pedro Britz, Jaqueline Almeida Pimentel, Mário Sérgio Fernandes, Hedi Gharsallah, Zied Hajjej, Walid Samoud, Oleg Grebenchikov, Valery Likhvantsev, Elena Stroiteleva, Nikolaos Markou, Dimitra Bakali, Dionysia Koutrafouri, Ahmed Subhy Alsheikhly, Angelo Giacomucci, Sara Maccherani, Janneke Horn, Mohamed Elbahnasawy, Arezoo Ahmadi, Lien Decaesteker, Daphne Decruyenaere, Ruth Demeersseman, Yves Devriendt, Karen Embo, Ditty van Duijn, Patricia Ormskerk, Melanie Glasbergen-van Beijeren, Hassane Njimi, Alain Cariou, Christophe Lelubre, Giuseppe Ristagno, Nino Stocchetti, Mauro Oddo, Cathy De Deyne, Giuseppe Citerio

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DOI: 10.1001/jamanetworkopen.2026.32555
Published: 2026-09-08
Container: JAMA Network Open
Publisher: American Medical Association (AMA)
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Cite this work

BibTeX

@article{allodium:10.1001/jamanetworkopen.2026.32555,
  title = {Restrictive vs Liberal Transfusion Strategy in Traumatic Brain Injury},
  author = {Irene Sbaraini Zernini and Chiara Faso and Carla Bittencourt Rynkowski and Kirsten Moller and Piet Lormans and Manuel Quintana Diaz and Anselmo Caricato and Marjorie Beumier and Evy Voets and Mario Arias and Herve Quintard and Diego Morocho and Pedro Kurtz and Erik Roman Pognuz and Olivier Huet and Ata Mahmoodpoor and Aaron Blandino-Ortiz and Sara Alcantara and Russell Chabanne and Francisco Cicho and Stan Popugaev and Angelo Giacomucci and Jamil Dibu and Raphael Cinotti and Pierre Bouzat and Jean-Louis Vincent and Elisa Gouvêa Bogossian and Fabio Silvio Taccone and Unknown and Claudia Díaz and Andrés Saravia and Ahmas Bayrlee and Laura Nedolast and Hussam Elkambergy and Haamid Siddique and Jihad Mallat and Nahla AlJaberi and Samer Shoshan and Ayo Mandi and Bruno De Oliveira and Malligere Prasanna and Rehan Haque and Dnyaneshwar Munde and Sara Chaffee and Fatma Alawadhi and Jamil Dibu and Eija Junttila and Teemu Luoto and Simona Šteblaj and Jacques Creteur and Dominique Durand and Caroline Abbenhuijs and Nancy Itesa Matumikina and Filippo Annoni and Leda Nobile and Miguel Ulloa Bersatti and Igor Yovenko and Alexander Tsarev and Jasperina Dubois and Evy Voets and Luc Janssen and Luigi Zattera and Leire Pedrosa and Berta Monleon Lopez and Ainhoa Serrano and Nekane Romero-García and Xavier Wittebole and Antonio M Dell'Anna and Camilla Gelormini and Eleonora Stival and Pilar Marcos Neira and Regina Roig Pineda and Lara Bielsa Berrocal and Maite Misis del Campo and Stepani Bendel and Jorge H Mejía-Mantilla and Ángela Marulanda and Wojciech Dabrowski and Rune Damgaard Nielsen and Markus Harboe Olsen and Helene Ravnholt Jensen and Ida Møller Larsen and Roberta Tallarico and Umberto Lucangelo and Maria Isabel Gonzales Perez and Carole Ichai and Karim Asenhoune and Karim Lakhal and Charlotte Fernandez-Canal and Samuel Gay and Marie Lebouc and David Bougon and Etienne Escudier and Michel Sirodot and Albrice Levrat and Alix Courouau and Jacques Duranteau and Aurore Rodrigues and Naima Makouche and Gilles Francony and Olivier Vincent and Perrine Boucheix and Clotilde Schilte and Anais Adolle and Thomas Gargadennec and Patricia Dias and Gwenaelle Desanglois and Alexia Meheut and Pauline Cam and Geert Meyfroidt and Liese Mebis and Alexandra Hendrickx and Pieetr Wouters and Sylvia Van Hulle and Alain D'Hondt and Marjorie Beumier and Marc Burgeois and Olivier Simonet and Frederic Vallot and Pablo Centeno and Matias Anchorena and Ximena Benavente and Maximilian D'Onofrio and Nydia Funes and Antonio Barra de Oca and Gabriela Izzo and Charlotte Castelain and Filippo Soetens and Mario Arias and Diego Morocho and Manuel Jabaja and Diego Tutillo and Stan Popugaev and Celeste Dias and Elena Perez Solada and Pilar Justo and Amparo Lopez Gomez and Sara Alcantara and Francisco Chico and Maria Fernanda Garcia and Fabricio Picoita and Stela Velasco Eichler and Gabriela Nonticuri Bianchi and João Pedro Britz and Jaqueline Almeida Pimentel and Mário Sérgio Fernandes and Hedi Gharsallah and Zied Hajjej and Walid Samoud and Oleg Grebenchikov and Valery Likhvantsev and Elena Stroiteleva and Nikolaos Markou and Dimitra Bakali and Dionysia Koutrafouri and Ahmed Subhy Alsheikhly and Angelo Giacomucci and Sara Maccherani and Janneke Horn and Mohamed Elbahnasawy and Arezoo Ahmadi and Lien Decaesteker and Daphne Decruyenaere and Ruth Demeersseman and Yves Devriendt and Karen Embo and Ditty van Duijn and Patricia Ormskerk and Melanie Glasbergen-van Beijeren and Hassane Njimi and Alain Cariou and Christophe Lelubre and Giuseppe Ristagno and Nino Stocchetti and Mauro Oddo and Cathy De Deyne and Giuseppe Citerio},
  year = {2026},
  journal = {JAMA Network Open},
  doi = {10.1001/jamanetworkopen.2026.32555},
  url = {https://doi.org/10.1001/jamanetworkopen.2026.32555}
}

RIS

TY  - JOUR
TI  - Restrictive vs Liberal Transfusion Strategy in Traumatic Brain Injury
AU  - Irene Sbaraini Zernini
AU  - Chiara Faso
AU  - Carla Bittencourt Rynkowski
AU  - Kirsten Moller
AU  - Piet Lormans
AU  - Manuel Quintana Diaz
AU  - Anselmo Caricato
AU  - Marjorie Beumier
AU  - Evy Voets
AU  - Mario Arias
AU  - Herve Quintard
AU  - Diego Morocho
AU  - Pedro Kurtz
AU  - Erik Roman Pognuz
AU  - Olivier Huet
AU  - Ata Mahmoodpoor
AU  - Aaron Blandino-Ortiz
AU  - Sara Alcantara
AU  - Russell Chabanne
AU  - Francisco Cicho
AU  - Stan Popugaev
AU  - Angelo Giacomucci
AU  - Jamil Dibu
AU  - Raphael Cinotti
AU  - Pierre Bouzat
AU  - Jean-Louis Vincent
AU  - Elisa Gouvêa Bogossian
AU  - Fabio Silvio Taccone
AU  - Unknown
AU  - Claudia Díaz
AU  - Andrés Saravia
AU  - Ahmas Bayrlee
AU  - Laura Nedolast
AU  - Hussam Elkambergy
AU  - Haamid Siddique
AU  - Jihad Mallat
AU  - Nahla AlJaberi
AU  - Samer Shoshan
AU  - Ayo Mandi
AU  - Bruno De Oliveira
AU  - Malligere Prasanna
AU  - Rehan Haque
AU  - Dnyaneshwar Munde
AU  - Sara Chaffee
AU  - Fatma Alawadhi
AU  - Jamil Dibu
AU  - Eija Junttila
AU  - Teemu Luoto
AU  - Simona Šteblaj
AU  - Jacques Creteur
AU  - Dominique Durand
AU  - Caroline Abbenhuijs
AU  - Nancy Itesa Matumikina
AU  - Filippo Annoni
AU  - Leda Nobile
AU  - Miguel Ulloa Bersatti
AU  - Igor Yovenko
AU  - Alexander Tsarev
AU  - Jasperina Dubois
AU  - Evy Voets
AU  - Luc Janssen
AU  - Luigi Zattera
AU  - Leire Pedrosa
AU  - Berta Monleon Lopez
AU  - Ainhoa Serrano
AU  - Nekane Romero-García
AU  - Xavier Wittebole
AU  - Antonio M Dell'Anna
AU  - Camilla Gelormini
AU  - Eleonora Stival
AU  - Pilar Marcos Neira
AU  - Regina Roig Pineda
AU  - Lara Bielsa Berrocal
AU  - Maite Misis del Campo
AU  - Stepani Bendel
AU  - Jorge H Mejía-Mantilla
AU  - Ángela Marulanda
AU  - Wojciech Dabrowski
AU  - Rune Damgaard Nielsen
AU  - Markus Harboe Olsen
AU  - Helene Ravnholt Jensen
AU  - Ida Møller Larsen
AU  - Roberta Tallarico
AU  - Umberto Lucangelo
AU  - Maria Isabel Gonzales Perez
AU  - Carole Ichai
AU  - Karim Asenhoune
AU  - Karim Lakhal
AU  - Charlotte Fernandez-Canal
AU  - Samuel Gay
AU  - Marie Lebouc
AU  - David Bougon
AU  - Etienne Escudier
AU  - Michel Sirodot
AU  - Albrice Levrat
AU  - Alix Courouau
AU  - Jacques Duranteau
AU  - Aurore Rodrigues
AU  - Naima Makouche
AU  - Gilles Francony
AU  - Olivier Vincent
AU  - Perrine Boucheix
AU  - Clotilde Schilte
AU  - Anais Adolle
AU  - Thomas Gargadennec
AU  - Patricia Dias
AU  - Gwenaelle Desanglois
AU  - Alexia Meheut
AU  - Pauline Cam
AU  - Geert Meyfroidt
AU  - Liese Mebis
AU  - Alexandra Hendrickx
AU  - Pieetr Wouters
AU  - Sylvia Van Hulle
AU  - Alain D'Hondt
AU  - Marjorie Beumier
AU  - Marc Burgeois
AU  - Olivier Simonet
AU  - Frederic Vallot
AU  - Pablo Centeno
AU  - Matias Anchorena
AU  - Ximena Benavente
AU  - Maximilian D'Onofrio
AU  - Nydia Funes
AU  - Antonio Barra de Oca
AU  - Gabriela Izzo
AU  - Charlotte Castelain
AU  - Filippo Soetens
AU  - Mario Arias
AU  - Diego Morocho
AU  - Manuel Jabaja
AU  - Diego Tutillo
AU  - Stan Popugaev
AU  - Celeste Dias
AU  - Elena Perez Solada
AU  - Pilar Justo
AU  - Amparo Lopez Gomez
AU  - Sara Alcantara
AU  - Francisco Chico
AU  - Maria Fernanda Garcia
AU  - Fabricio Picoita
AU  - Stela Velasco Eichler
AU  - Gabriela Nonticuri Bianchi
AU  - João Pedro Britz
AU  - Jaqueline Almeida Pimentel
AU  - Mário Sérgio Fernandes
AU  - Hedi Gharsallah
AU  - Zied Hajjej
AU  - Walid Samoud
AU  - Oleg Grebenchikov
AU  - Valery Likhvantsev
AU  - Elena Stroiteleva
AU  - Nikolaos Markou
AU  - Dimitra Bakali
AU  - Dionysia Koutrafouri
AU  - Ahmed Subhy Alsheikhly
AU  - Angelo Giacomucci
AU  - Sara Maccherani
AU  - Janneke Horn
AU  - Mohamed Elbahnasawy
AU  - Arezoo Ahmadi
AU  - Lien Decaesteker
AU  - Daphne Decruyenaere
AU  - Ruth Demeersseman
AU  - Yves Devriendt
AU  - Karen Embo
AU  - Ditty van Duijn
AU  - Patricia Ormskerk
AU  - Melanie Glasbergen-van Beijeren
AU  - Hassane Njimi
AU  - Alain Cariou
AU  - Christophe Lelubre
AU  - Giuseppe Ristagno
AU  - Nino Stocchetti
AU  - Mauro Oddo
AU  - Cathy De Deyne
AU  - Giuseppe Citerio
PY  - 2026
JO  - JAMA Network Open
DO  - 10.1001/jamanetworkopen.2026.32555
UR  - https://doi.org/10.1001/jamanetworkopen.2026.32555
ER  -

APA

Zernini, I. S., Faso, C., Rynkowski, C. B., Moller, K., Lormans, P., Diaz, M. Q., Caricato, A., Beumier, M., Voets, E., Arias, M., Quintard, H., Morocho, D., Kurtz, P., Pognuz, E. R., Huet, O., Mahmoodpoor, A., Blandino-Ortiz, A., Alcantara, S., Chabanne, R., Cicho, F., Popugaev, S., Giacomucci, A., Dibu, J., Cinotti, R., Bouzat, P., Vincent, J., Bogossian, E. G., Taccone, F. S., Unknown, Díaz, C., Saravia, A., Bayrlee, A., Nedolast, L., Elkambergy, H., Siddique, H., Mallat, J., AlJaberi, N., Shoshan, S., Mandi, A., Oliveira, B. D., Prasanna, M., Haque, R., Munde, D., Chaffee, S., Alawadhi, F., Dibu, J., Junttila, E., Luoto, T., Šteblaj, S., Creteur, J., Durand, D., Abbenhuijs, C., Matumikina, N. I., Annoni, F., Nobile, L., Bersatti, M. U., Yovenko, I., Tsarev, A., Dubois, J., Voets, E., Janssen, L., Zattera, L., Pedrosa, L., Lopez, B. M., Serrano, A., Romero-García, N., Wittebole, X., Dell'Anna, A. M., Gelormini, C., Stival, E., Neira, P. M., Pineda, R. R., Berrocal, L. B., Campo, M. M. D., Bendel, S., Mejía-Mantilla, J. H., Marulanda, Á., Dabrowski, W., Nielsen, R. D., Olsen, M. H., Jensen, H. R., Larsen, I. M., Tallarico, R., Lucangelo, U., Perez, M. I. G., Ichai, C., Asenhoune, K., Lakhal, K., Fernandez-Canal, C., Gay, S., Lebouc, M., Bougon, D., Escudier, E., Sirodot, M., Levrat, A., Courouau, A., Duranteau, J., Rodrigues, A., Makouche, N., Francony, G., Vincent, O., Boucheix, P., Schilte, C., Adolle, A., Gargadennec, T., Dias, P., Desanglois, G., Meheut, A., Cam, P., Meyfroidt, G., Mebis, L., Hendrickx, A., Wouters, P., Hulle, S. V., D'Hondt, A., Beumier, M., Burgeois, M., Simonet, O., Vallot, F., Centeno, P., Anchorena, M., Benavente, X., D'Onofrio, M., Funes, N., Oca, A. B. D., Izzo, G., Castelain, C., Soetens, F., Arias, M., Morocho, D., Jabaja, M., Tutillo, D., Popugaev, S., Dias, C., Solada, E. P., Justo, P., Gomez, A. L., Alcantara, S., Chico, F., Garcia, M. F., Picoita, F., Eichler, S. V., Bianchi, G. N., Britz, J. P., Pimentel, J. A., Fernandes, M. S., Gharsallah, H., Hajjej, Z., Samoud, W., Grebenchikov, O., Likhvantsev, V., Stroiteleva, E., Markou, N., Bakali, D., Koutrafouri, D., Alsheikhly, A. S., Giacomucci, A., Maccherani, S., Horn, J., Elbahnasawy, M., Ahmadi, A., Decaesteker, L., Decruyenaere, D., Demeersseman, R., Devriendt, Y., Embo, K., Duijn, D. V., Ormskerk, P., Beijeren, M. G., Njimi, H., Cariou, A., Lelubre, C., Ristagno, G., Stocchetti, N., Oddo, M., Deyne, C. D., & Citerio, G. (2026). Restrictive vs Liberal Transfusion Strategy in Traumatic Brain Injury. JAMA Network Open. https://doi.org/10.1001/jamanetworkopen.2026.32555

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