Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer.

Brummel BR, Kokkaliari S, Gao Q, Chen J, de Almeida LC, Tenneti S, Leas DA, Levit E, Alexander LS, Abboud KA, Wei P, Cameron MD, Rocca JR, Ratnayake R, Zhang DD, Luesch H, Huigens RW 3rd

Open source

DOI
10.1002/advs.202512849
Published
2026 Jul
Container
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Publisher
Not recorded
Open access
yes

Credibility signals

uncertain Score 53/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1002/advs.202512849,
  title = {Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer.},
  author = {Brummel BR and Kokkaliari S and Gao Q and Chen J and de Almeida LC and Tenneti S and Leas DA and Levit E and Alexander LS and Abboud KA and Wei P and Cameron MD and Rocca JR and Ratnayake R and Zhang DD and Luesch H and Huigens RW 3rd},
  year = {2026},
  journal = {Advanced science (Weinheim, Baden-Wurttemberg, Germany)},
  doi = {10.1002/advs.202512849},
  url = {https://doi.org/10.1002/advs.202512849}
}

RIS

TY  - JOUR
TI  - Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer.
AU  - Brummel BR
AU  - Kokkaliari S
AU  - Gao Q
AU  - Chen J
AU  - de Almeida LC
AU  - Tenneti S
AU  - Leas DA
AU  - Levit E
AU  - Alexander LS
AU  - Abboud KA
AU  - Wei P
AU  - Cameron MD
AU  - Rocca JR
AU  - Ratnayake R
AU  - Zhang DD
AU  - Luesch H
AU  - Huigens RW 3rd
PY  - 2026
JO  - Advanced science (Weinheim, Baden-Wurttemberg, Germany)
DO  - 10.1002/advs.202512849
UR  - https://doi.org/10.1002/advs.202512849
ER  - 

APA

BR, B., S, K., Q, G., J, C., LC, D. A., S, T., DA, L., E, L., LS, A., KA, A., P, W., MD, C., JR, R., R, R., DD, Z., H, L., & 3rd, H. R. (2026). Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer.. Advanced science (Weinheim, Baden-Wurttemberg, Germany). https://doi.org/10.1002/advs.202512849

Source records