Thinking Outside the Binding Site: A Self‐Encapsulating Kinase Inhibitor Remodels Its Pocket to Achieve Selectivity

Nico J. Seidler, Monica R. MacDonald, Athina A. Moschopoulou, Sahba Cunningham, Tess M. Weber, Nader N. Nasief, Lorenz Mayer, Frederik W. Hacker, Ekaterina Hermann, Mareike B. Möllers, Yuliia Skliarenko, Tahereh Damghani, Abid N. Manzar, Kaly S. Lin, Ramona Rudalska, Marcia I. Goettert, Lars Zender, Daniel Dauch, Michael Forster, Stefan A. Laufer, David E. Heppner

Open source

DOI: 10.1002/anie.2953141
Published: 2026-09-15
Container: Angewandte Chemie International Edition
Publisher: Wiley
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1002/anie.2953141,
  title = {Thinking Outside the Binding Site: A Self‐Encapsulating Kinase Inhibitor Remodels Its Pocket to Achieve Selectivity},
  author = {Nico J. Seidler and Monica R. MacDonald and Athina A. Moschopoulou and Sahba Cunningham and Tess M. Weber and Nader N. Nasief and Lorenz Mayer and Frederik W. Hacker and Ekaterina Hermann and Mareike B. Möllers and Yuliia Skliarenko and Tahereh Damghani and Abid N. Manzar and Kaly S. Lin and Ramona Rudalska and Marcia I. Goettert and Lars Zender and Daniel Dauch and Michael Forster and Stefan A. Laufer and David E. Heppner},
  year = {2026},
  journal = {Angewandte Chemie International Edition},
  doi = {10.1002/anie.2953141},
  url = {https://doi.org/10.1002/anie.2953141}
}

RIS

TY  - JOUR
TI  - Thinking Outside the Binding Site: A Self‐Encapsulating Kinase Inhibitor Remodels Its Pocket to Achieve Selectivity
AU  - Nico J. Seidler
AU  - Monica R. MacDonald
AU  - Athina A. Moschopoulou
AU  - Sahba Cunningham
AU  - Tess M. Weber
AU  - Nader N. Nasief
AU  - Lorenz Mayer
AU  - Frederik W. Hacker
AU  - Ekaterina Hermann
AU  - Mareike B. Möllers
AU  - Yuliia Skliarenko
AU  - Tahereh Damghani
AU  - Abid N. Manzar
AU  - Kaly S. Lin
AU  - Ramona Rudalska
AU  - Marcia I. Goettert
AU  - Lars Zender
AU  - Daniel Dauch
AU  - Michael Forster
AU  - Stefan A. Laufer
AU  - David E. Heppner
PY  - 2026
JO  - Angewandte Chemie International Edition
DO  - 10.1002/anie.2953141
UR  - https://doi.org/10.1002/anie.2953141
ER  -

APA

Seidler, N. J., MacDonald, M. R., Moschopoulou, A. A., Cunningham, S., Weber, T. M., Nasief, N. N., Mayer, L., Hacker, F. W., Hermann, E., Möllers, M. B., Skliarenko, Y., Damghani, T., Manzar, A. N., Lin, K. S., Rudalska, R., Goettert, M. I., Zender, L., Dauch, D., Forster, M., Laufer, S. A., & Heppner, D. E. (2026). Thinking Outside the Binding Site: A Self‐Encapsulating Kinase Inhibitor Remodels Its Pocket to Achieve Selectivity. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.2953141

Source records

crossref · retrieved 2026-09-25T00:31:23.496Z