Direct Comparison Between Loss-to-Follow-Up and Statistical Fragility Is Methodologically Inappropriate, and Fragility Reflects the P Value, Not Trial Robustness: A Simulation Analysis of 300,000 Randomized Controlled Trials.

Vivekanantha P, Son H, Kay J, Kotipalli S, Bouchard MD, Madden K, Simunovic N, Ayeni OR

DOI: 10.1002/arj.70457
Published: 2026 Aug 16
Container: Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Publisher: Not recorded
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1002/arj.70457,
  title = {Direct Comparison Between Loss-to-Follow-Up and Statistical Fragility Is Methodologically Inappropriate, and Fragility Reflects the P Value, Not Trial Robustness: A Simulation Analysis of 300,000 Randomized Controlled Trials.},
  author = {Vivekanantha P and Son H and Kay J and Kotipalli S and Bouchard MD and Madden K and Simunovic N and Ayeni OR},
  year = {2026},
  journal = {Arthroscopy : the journal of arthroscopic \& related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association},
  doi = {10.1002/arj.70457},
  url = {https://doi.org/10.1002/arj.70457}
}

RIS

TY  - JOUR
TI  - Direct Comparison Between Loss-to-Follow-Up and Statistical Fragility Is Methodologically Inappropriate, and Fragility Reflects the P Value, Not Trial Robustness: A Simulation Analysis of 300,000 Randomized Controlled Trials.
AU  - Vivekanantha P
AU  - Son H
AU  - Kay J
AU  - Kotipalli S
AU  - Bouchard MD
AU  - Madden K
AU  - Simunovic N
AU  - Ayeni OR
PY  - 2026
JO  - Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
DO  - 10.1002/arj.70457
UR  - https://doi.org/10.1002/arj.70457
ER  -

APA

P, V., H, S., J, K., S, K., MD, B., K, M., N, S., & OR, A. (2026). Direct Comparison Between Loss-to-Follow-Up and Statistical Fragility Is Methodologically Inappropriate, and Fragility Reflects the P Value, Not Trial Robustness: A Simulation Analysis of 300,000 Randomized Controlled Trials.. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. https://doi.org/10.1002/arj.70457

Source records

pubmed · retrieved 2026-09-25T20:37:11.076Z