Probing 3-Amino-2H-Azaindazoles as Allosteric Inhibitors of the Protein Tyrosine Phosphatase SHP2.

Amoussa M, Efrém NL, Li F, Guo Z, Roske Y, Frank KJ, Pach S, Wolf CA, Bo F, Lesina M, Kintzel M, Alsalim R, Zeitz V, Csorba N, Radetzki S, Keserű GM, Daumke O, Algül H, Wolber G, Li J, Nazaré M

Open source

DOI: 10.1002/cmdc.70341
Published: 2026 Jun 15
Container: ChemMedChem
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1002/cmdc.70341,
  title = {Probing 3-Amino-2H-Azaindazoles as Allosteric Inhibitors of the Protein Tyrosine Phosphatase SHP2.},
  author = {Amoussa M and Efrém NL and Li F and Guo Z and Roske Y and Frank KJ and Pach S and Wolf CA and Bo F and Lesina M and Kintzel M and Alsalim R and Zeitz V and Csorba N and Radetzki S and Keserű GM and Daumke O and Algül H and Wolber G and Li J and Nazaré M},
  year = {2026},
  journal = {ChemMedChem},
  doi = {10.1002/cmdc.70341},
  url = {https://doi.org/10.1002/cmdc.70341}
}

RIS

TY  - JOUR
TI  - Probing 3-Amino-2H-Azaindazoles as Allosteric Inhibitors of the Protein Tyrosine Phosphatase SHP2.
AU  - Amoussa M
AU  - Efrém NL
AU  - Li F
AU  - Guo Z
AU  - Roske Y
AU  - Frank KJ
AU  - Pach S
AU  - Wolf CA
AU  - Bo F
AU  - Lesina M
AU  - Kintzel M
AU  - Alsalim R
AU  - Zeitz V
AU  - Csorba N
AU  - Radetzki S
AU  - Keserű GM
AU  - Daumke O
AU  - Algül H
AU  - Wolber G
AU  - Li J
AU  - Nazaré M
PY  - 2026
JO  - ChemMedChem
DO  - 10.1002/cmdc.70341
UR  - https://doi.org/10.1002/cmdc.70341
ER  -

APA

M, A., NL, E., F, L., Z, G., Y, R., KJ, F., S, P., CA, W., F, B., M, L., M, K., R, A., V, Z., N, C., S, R., GM, K., O, D., H, A., G, W., J, L., & M, N. (2026). Probing 3-Amino-2H-Azaindazoles as Allosteric Inhibitors of the Protein Tyrosine Phosphatase SHP2.. ChemMedChem. https://doi.org/10.1002/cmdc.70341

Source records

pubmed · retrieved 2026-09-25T11:54:41.567Z