Topliss-Guided Optimization of Acetanilide-Based Soluble Epoxide Hydrolase Inhibitors: Exploring the Pentafluorosulfanyl Group as a Potency-Enhancing Motif.

López-Ruiz A, Pujol E, Ramos C, Rizzo V, Morisseau C, Val C, Ginex T, Vázquez J, Codony S, Turcu AL, Pérez B, Sáez E, Pineda-Lucena A, Hammock BD, Luque FJ, Loza MI, Brea J, Vázquez S.

Open source

DOI
10.1002/cmdc.70430
Published
2026-08-01
Container
ChemMedChem
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.1002/cmdc.70430,
  title = {Topliss-Guided Optimization of Acetanilide-Based Soluble Epoxide Hydrolase Inhibitors: Exploring the Pentafluorosulfanyl Group as a Potency-Enhancing Motif.},
  author = {López-Ruiz A and  Pujol E and  Ramos C and  Rizzo V and  Morisseau C and  Val C and  Ginex T and  Vázquez J and  Codony S and  Turcu AL and  Pérez B and  Sáez E and  Pineda-Lucena A and  Hammock BD and  Luque FJ and  Loza MI and  Brea J and  Vázquez S.},
  year = {2026},
  journal = {ChemMedChem},
  doi = {10.1002/cmdc.70430},
  url = {https://doi.org/10.1002/cmdc.70430}
}

RIS

TY  - JOUR
TI  - Topliss-Guided Optimization of Acetanilide-Based Soluble Epoxide Hydrolase Inhibitors: Exploring the Pentafluorosulfanyl Group as a Potency-Enhancing Motif.
AU  - López-Ruiz A
AU  -  Pujol E
AU  -  Ramos C
AU  -  Rizzo V
AU  -  Morisseau C
AU  -  Val C
AU  -  Ginex T
AU  -  Vázquez J
AU  -  Codony S
AU  -  Turcu AL
AU  -  Pérez B
AU  -  Sáez E
AU  -  Pineda-Lucena A
AU  -  Hammock BD
AU  -  Luque FJ
AU  -  Loza MI
AU  -  Brea J
AU  -  Vázquez S.
PY  - 2026
JO  - ChemMedChem
DO  - 10.1002/cmdc.70430
UR  - https://doi.org/10.1002/cmdc.70430
ER  - 

APA

A, L., E, P., C, R., V, R., C, M., C, V., T, G., J, V., S, C., AL, T., B, P., E, S., A, P., BD, H., FJ, L., MI, L., J, B., & S., V. (2026). Topliss-Guided Optimization of Acetanilide-Based Soluble Epoxide Hydrolase Inhibitors: Exploring the Pentafluorosulfanyl Group as a Potency-Enhancing Motif.. ChemMedChem. https://doi.org/10.1002/cmdc.70430

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