Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis.

Saddoughi SA, Gencer S, Peterson YK, Ward KE, Mukhopadhyay A, Oaks J, Bielawski J, Szulc ZM, Thomas RJ, Selvam SP, Senkal CE, Garrett-Mayer E, De Palma RM, Fedarovich D, Liu A, Habib AA, Stahelin RV, Perrotti D, Ogretmen B

Open source

DOI: 10.1002/emmm.201201283
Published: 2013 Jan
Container: EMBO molecular medicine
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1002/emmm.201201283,
  title = {Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis.},
  author = {Saddoughi SA and Gencer S and Peterson YK and Ward KE and Mukhopadhyay A and Oaks J and Bielawski J and Szulc ZM and Thomas RJ and Selvam SP and Senkal CE and Garrett-Mayer E and De Palma RM and Fedarovich D and Liu A and Habib AA and Stahelin RV and Perrotti D and Ogretmen B},
  year = {2013},
  journal = {EMBO molecular medicine},
  doi = {10.1002/emmm.201201283},
  url = {https://doi.org/10.1002/emmm.201201283}
}

RIS

TY  - JOUR
TI  - Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis.
AU  - Saddoughi SA
AU  - Gencer S
AU  - Peterson YK
AU  - Ward KE
AU  - Mukhopadhyay A
AU  - Oaks J
AU  - Bielawski J
AU  - Szulc ZM
AU  - Thomas RJ
AU  - Selvam SP
AU  - Senkal CE
AU  - Garrett-Mayer E
AU  - De Palma RM
AU  - Fedarovich D
AU  - Liu A
AU  - Habib AA
AU  - Stahelin RV
AU  - Perrotti D
AU  - Ogretmen B
PY  - 2013
JO  - EMBO molecular medicine
DO  - 10.1002/emmm.201201283
UR  - https://doi.org/10.1002/emmm.201201283
ER  -

APA

SA, S., S, G., YK, P., KE, W., A, M., J, O., J, B., ZM, S., RJ, T., SP, S., CE, S., E, G., RM, D. P., D, F., A, L., AA, H., RV, S., D, P., & B, O. (2013). Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis.. EMBO molecular medicine. https://doi.org/10.1002/emmm.201201283

Source records

pubmed · retrieved 2026-11-10T06:47:11.930Z
europe-pmc · retrieved 2026-11-10T06:47:11.942Z
doaj · retrieved 2026-11-10T06:47:11.949Z