Effects of a clinical metagenomics intervention on clinical outcomes, healthcare costs, and health-related quality of life in patients with sepsis or septic shock: results of the randomized-controlled DigiSep trial

Thorsten Brenner, Annabell Skarabis, Stefan J. Schaller, Thilo von Groote, Christian Putensen, Ulf Günther, Martin Sauer, Sebastian O. Decker, Fabian Dusse, Manfred Weiss, Klaudiusz Suchodolski, Tim-Philipp Simon, Peter Rosenberger, Onnen Moerer, Matthias Unterberg, Jens-Christian Schewe, Hendrik Bracht, Selina Hutzl, Manuel Feißt, Ursula Marschall, Patrick Brandenburg, Philip Stevens, Juliana Schmidt, Mathias W. Pletz, Marc M. Berger, Unknown, Jens Brands, Alberto Antinoro, Linus O. Warner, Markus A. Weigand, Dominique M. Hart, Gernot Marx, Jana Mossanen, Thomas Breuer, Helene Häberle, Kristina Nitzsche, Paul Thalmann, Jolanda Brezinski, Joachim Saam, Silke Grumaz, Maren Steinmann, Maxime Gaasch, Bastian Pasieka, Ulrike Jaekel, Timo Brandenburger, Friedhelm Bach, Haitham Mutlak, Stefan Utzolino, Wolfgang A. Krueger, Stefan Hagel, Christian Lanckohr

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DOI
10.1007/s00134-026-08521-3
Published
2026-06-30
Container
Intensive Care Medicine
Publisher
Springer Science and Business Media LLC
Open access
unknown

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BibTeX

@article{allodium:10.1007/s00134-026-08521-3,
  title = {Effects of a clinical metagenomics intervention on clinical outcomes, healthcare costs, and health-related quality of life in patients with sepsis or septic shock: results of the randomized-controlled DigiSep trial},
  author = {Thorsten Brenner and Annabell Skarabis and Stefan J. Schaller and Thilo von Groote and Christian Putensen and Ulf Günther and Martin Sauer and Sebastian O. Decker and Fabian Dusse and Manfred Weiss and Klaudiusz Suchodolski and Tim-Philipp Simon and Peter Rosenberger and Onnen Moerer and Matthias Unterberg and Jens-Christian Schewe and Hendrik Bracht and Selina Hutzl and Manuel Feißt and Ursula Marschall and Patrick Brandenburg and Philip Stevens and Juliana Schmidt and Mathias W. Pletz and Marc M. Berger and Unknown and Jens Brands and Alberto Antinoro and Linus O. Warner and Markus A. Weigand and Dominique M. Hart and Gernot Marx and Jana Mossanen and Thomas Breuer and Helene Häberle and Kristina Nitzsche and Paul Thalmann and Jolanda Brezinski and Joachim Saam and Silke Grumaz and Maren Steinmann and Maxime Gaasch and Bastian Pasieka and Ulrike Jaekel and Timo Brandenburger and Friedhelm Bach and Haitham Mutlak and Stefan Utzolino and Wolfgang A. Krueger and Stefan Hagel and Christian Lanckohr},
  year = {2026},
  journal = {Intensive Care Medicine},
  doi = {10.1007/s00134-026-08521-3},
  url = {https://doi.org/10.1007/s00134-026-08521-3}
}

RIS

TY  - JOUR
TI  - Effects of a clinical metagenomics intervention on clinical outcomes, healthcare costs, and health-related quality of life in patients with sepsis or septic shock: results of the randomized-controlled DigiSep trial
AU  - Thorsten Brenner
AU  - Annabell Skarabis
AU  - Stefan J. Schaller
AU  - Thilo von Groote
AU  - Christian Putensen
AU  - Ulf Günther
AU  - Martin Sauer
AU  - Sebastian O. Decker
AU  - Fabian Dusse
AU  - Manfred Weiss
AU  - Klaudiusz Suchodolski
AU  - Tim-Philipp Simon
AU  - Peter Rosenberger
AU  - Onnen Moerer
AU  - Matthias Unterberg
AU  - Jens-Christian Schewe
AU  - Hendrik Bracht
AU  - Selina Hutzl
AU  - Manuel Feißt
AU  - Ursula Marschall
AU  - Patrick Brandenburg
AU  - Philip Stevens
AU  - Juliana Schmidt
AU  - Mathias W. Pletz
AU  - Marc M. Berger
AU  - Unknown
AU  - Jens Brands
AU  - Alberto Antinoro
AU  - Linus O. Warner
AU  - Markus A. Weigand
AU  - Dominique M. Hart
AU  - Gernot Marx
AU  - Jana Mossanen
AU  - Thomas Breuer
AU  - Helene Häberle
AU  - Kristina Nitzsche
AU  - Paul Thalmann
AU  - Jolanda Brezinski
AU  - Joachim Saam
AU  - Silke Grumaz
AU  - Maren Steinmann
AU  - Maxime Gaasch
AU  - Bastian Pasieka
AU  - Ulrike Jaekel
AU  - Timo Brandenburger
AU  - Friedhelm Bach
AU  - Haitham Mutlak
AU  - Stefan Utzolino
AU  - Wolfgang A. Krueger
AU  - Stefan Hagel
AU  - Christian Lanckohr
PY  - 2026
JO  - Intensive Care Medicine
DO  - 10.1007/s00134-026-08521-3
UR  - https://doi.org/10.1007/s00134-026-08521-3
ER  - 

APA

Brenner, T., Skarabis, A., Schaller, S. J., Groote, T. V., Putensen, C., Günther, U., Sauer, M., Decker, S. O., Dusse, F., Weiss, M., Suchodolski, K., Simon, T., Rosenberger, P., Moerer, O., Unterberg, M., Schewe, J., Bracht, H., Hutzl, S., Feißt, M., Marschall, U., Brandenburg, P., Stevens, P., Schmidt, J., Pletz, M. W., Berger, M. M., Unknown, Brands, J., Antinoro, A., Warner, L. O., Weigand, M. A., Hart, D. M., Marx, G., Mossanen, J., Breuer, T., Häberle, H., Nitzsche, K., Thalmann, P., Brezinski, J., Saam, J., Grumaz, S., Steinmann, M., Gaasch, M., Pasieka, B., Jaekel, U., Brandenburger, T., Bach, F., Mutlak, H., Utzolino, S., Krueger, W. A., Hagel, S., & Lanckohr, C. (2026). Effects of a clinical metagenomics intervention on clinical outcomes, healthcare costs, and health-related quality of life in patients with sepsis or septic shock: results of the randomized-controlled DigiSep trial. Intensive Care Medicine. https://doi.org/10.1007/s00134-026-08521-3

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