Targeting the PI3K/AKT/mTOR pathway in gastrointestinal cancers: a comprehensive review of mechanisms, preclinical evidence, and clinical challenges

Faride Kaikavoosnejad, Hamed Haddad Kashani, Khadijeh Dizaji Asl, Zeinab Mazloumi, Ali Keyhani, Seyyede Sepide Ashraf Moosavi, Milad Verdi, Ali Rafat

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DOI: 10.1007/s12032-026-03374-8
Published: 2026-08-29
Container: Medical Oncology
Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1007/s12032-026-03374-8,
  title = {Targeting the PI3K/AKT/mTOR pathway in gastrointestinal cancers: a comprehensive review of mechanisms, preclinical evidence, and clinical challenges},
  author = {Faride Kaikavoosnejad and Hamed Haddad Kashani and Khadijeh Dizaji Asl and Zeinab Mazloumi and Ali Keyhani and Seyyede Sepide Ashraf Moosavi and Milad Verdi and Ali Rafat},
  year = {2026},
  journal = {Medical Oncology},
  doi = {10.1007/s12032-026-03374-8},
  url = {https://doi.org/10.1007/s12032-026-03374-8}
}

RIS

TY  - JOUR
TI  - Targeting the PI3K/AKT/mTOR pathway in gastrointestinal cancers: a comprehensive review of mechanisms, preclinical evidence, and clinical challenges
AU  - Faride Kaikavoosnejad
AU  - Hamed Haddad Kashani
AU  - Khadijeh Dizaji Asl
AU  - Zeinab Mazloumi
AU  - Ali Keyhani
AU  - Seyyede Sepide Ashraf Moosavi
AU  - Milad Verdi
AU  - Ali Rafat
PY  - 2026
JO  - Medical Oncology
DO  - 10.1007/s12032-026-03374-8
UR  - https://doi.org/10.1007/s12032-026-03374-8
ER  -

APA

Kaikavoosnejad, F., Kashani, H. H., Asl, K. D., Mazloumi, Z., Keyhani, A., Moosavi, S. S. A., Verdi, M., & Rafat, A. (2026). Targeting the PI3K/AKT/mTOR pathway in gastrointestinal cancers: a comprehensive review of mechanisms, preclinical evidence, and clinical challenges. Medical Oncology. https://doi.org/10.1007/s12032-026-03374-8

Source records

crossref · retrieved 2026-09-25T07:24:47.293Z