Physiologically Based Pharmacokinetic Modeling of Elexacaftor–Tezacaftor–Ivacaftor in Adults and Pediatric People with Cystic Fibrosis: Exploring Brain Exposure and Neuropsychiatric Adverse Events

Clotilde Vellat, Laurent Bourguignon, Sabine Cohen, Philippe Reix, Romain Garreau

Open source

DOI
10.1007/s40262-026-01712-7
Published
2026-10-09
Container
Clinical Pharmacokinetics
Publisher
Springer Science and Business Media LLC
Open access
unknown

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BibTeX

@article{allodium:10.1007/s40262-026-01712-7,
  title = {Physiologically Based Pharmacokinetic Modeling of Elexacaftor–Tezacaftor–Ivacaftor in Adults and Pediatric People with Cystic Fibrosis: Exploring Brain Exposure and Neuropsychiatric Adverse Events},
  author = {Clotilde Vellat and Laurent Bourguignon and Sabine Cohen and Philippe Reix and Romain Garreau},
  year = {2026},
  journal = {Clinical Pharmacokinetics},
  doi = {10.1007/s40262-026-01712-7},
  url = {https://doi.org/10.1007/s40262-026-01712-7}
}

RIS

TY  - JOUR
TI  - Physiologically Based Pharmacokinetic Modeling of Elexacaftor–Tezacaftor–Ivacaftor in Adults and Pediatric People with Cystic Fibrosis: Exploring Brain Exposure and Neuropsychiatric Adverse Events
AU  - Clotilde Vellat
AU  - Laurent Bourguignon
AU  - Sabine Cohen
AU  - Philippe Reix
AU  - Romain Garreau
PY  - 2026
JO  - Clinical Pharmacokinetics
DO  - 10.1007/s40262-026-01712-7
UR  - https://doi.org/10.1007/s40262-026-01712-7
ER  - 

APA

Vellat, C., Bourguignon, L., Cohen, S., Reix, P., & Garreau, R. (2026). Physiologically Based Pharmacokinetic Modeling of Elexacaftor–Tezacaftor–Ivacaftor in Adults and Pediatric People with Cystic Fibrosis: Exploring Brain Exposure and Neuropsychiatric Adverse Events. Clinical Pharmacokinetics. https://doi.org/10.1007/s40262-026-01712-7

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