Phase Ib and dose-expansion study of GSK3326595, a PRMT5 inhibitor as monotherapy and in combination with pembrolizumab in patients with advanced cancers.

Gounder MM, Martin-Romano P, Italiano A, Siu LL, Cassier PA, Falchook GS, Lossos IS, Rasco DW, Hilton JF, McKean MA, Opdam FL, Strauss J, De Jonge M, Vermaat JSP, Crossman T, Zajac M, Tarkar A, Gonzalez Carreras F, Kremer BE, Barbash O, Segal S, Parasrampuria R, Postel-Vinay S

Open source

DOI
10.1016/j.annonc.2025.08.3757
Published
2025 Dec
Container
Annals of oncology : official journal of the European Society for Medical Oncology
Publisher
Not recorded
Open access
unknown

Credibility signals

limited evidence Score 43/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1016/j.annonc.2025.08.3757,
  title = {Phase Ib and dose-expansion study of GSK3326595, a PRMT5 inhibitor as monotherapy and in combination with pembrolizumab in patients with advanced cancers.},
  author = {Gounder MM and Martin-Romano P and Italiano A and Siu LL and Cassier PA and Falchook GS and Lossos IS and Rasco DW and Hilton JF and McKean MA and Opdam FL and Strauss J and De Jonge M and Vermaat JSP and Crossman T and Zajac M and Tarkar A and Gonzalez Carreras F and Kremer BE and Barbash O and Segal S and Parasrampuria R and Postel-Vinay S},
  year = {2025},
  journal = {Annals of oncology : official journal of the European Society for Medical Oncology},
  doi = {10.1016/j.annonc.2025.08.3757},
  url = {https://doi.org/10.1016/j.annonc.2025.08.3757}
}

RIS

TY  - JOUR
TI  - Phase Ib and dose-expansion study of GSK3326595, a PRMT5 inhibitor as monotherapy and in combination with pembrolizumab in patients with advanced cancers.
AU  - Gounder MM
AU  - Martin-Romano P
AU  - Italiano A
AU  - Siu LL
AU  - Cassier PA
AU  - Falchook GS
AU  - Lossos IS
AU  - Rasco DW
AU  - Hilton JF
AU  - McKean MA
AU  - Opdam FL
AU  - Strauss J
AU  - De Jonge M
AU  - Vermaat JSP
AU  - Crossman T
AU  - Zajac M
AU  - Tarkar A
AU  - Gonzalez Carreras F
AU  - Kremer BE
AU  - Barbash O
AU  - Segal S
AU  - Parasrampuria R
AU  - Postel-Vinay S
PY  - 2025
JO  - Annals of oncology : official journal of the European Society for Medical Oncology
DO  - 10.1016/j.annonc.2025.08.3757
UR  - https://doi.org/10.1016/j.annonc.2025.08.3757
ER  - 

APA

MM, G., P, M., A, I., LL, S., PA, C., GS, F., IS, L., DW, R., JF, H., MA, M., FL, O., J, S., M, D. J., JSP, V., T, C., M, Z., A, T., F, G. C., BE, K., O, B., S, S., R, P., & S, P. (2025). Phase Ib and dose-expansion study of GSK3326595, a PRMT5 inhibitor as monotherapy and in combination with pembrolizumab in patients with advanced cancers.. Annals of oncology : official journal of the European Society for Medical Oncology. https://doi.org/10.1016/j.annonc.2025.08.3757

Source records