Impact of the polymerase acidic protein E199K substitution in influenza A viruses on baloxavir susceptibility

Emi Takashita, Yoshihiro Yasui, Asaka Ikegaya, Kyohei Saka, Noriyuki Maeshiro, Hiroko Morita, Shiho Nagata, Seiichiro Fujisaki, Hideka Miura, Noriko Kishida, Kazuya Nakamura, Masayuki Shirakura, Shinji Watanabe, Hideki Hasegawa, Kazuya Mitsuhashi, Asami Ohnishi, Tomoko Takahashi, Yuko Suzuki, Minako Ato, Youko Fujiya, Naomi Ogawa, Nozomi Saito, Miyako Kon, Ayari Ikeda, Asaka Okubo, Yuki Wakabayashi, Akira Wakatsuki, Rina Kubota, Yoshiyuki Makino, Yasuo Kaburagi, Hitomi Yahata, Tomofumi Seno, Mami Nagashima, Kohei Shimizu, Chie Akaboshi, Yumiko Nagasawa, Kaori Imura, Miho Kitazume, Michiko Takeuchi, Erina Miyajima, Isako Onoda, Hirosato Ehara, Ryota Akaike, Takahisa Shimada, Nao Kobashi, Nobushige Sakai, Masahiro Nishioka, Yusuke Sato, Masakazu Suzuki, Takuya Yano, Asa Tanino, Kazuko Nakagawa, Saeko Morikawa, Hideki Mizutani, Tomohiro Oshibe, Ai Mori, Saya Yamamoto, Shiho Nagase, Yutaka Ueda, Yurie Kanba, Manabu Ishii, Yukie Shimazu, Yasutsugu Kawahara, Mitsuhiro Kameyama, Mizuki Yamamoto, Yukari Tsuchida, Sayako Yoshida, Wataru Satou, Yuri Kondo, Michihiko Miyamoto, Sonoko Izumida, Ukyo Osoegawa, Yumika Takaki, Mayumi Kadoguchi, Minoru Ikeda, Nami Tsuru

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DOI: 10.1016/j.antiviral.2025.106173
Published: 2025-07
Container: Antiviral Research
Publisher: Elsevier BV
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1016/j.antiviral.2025.106173,
  title = {Impact of the polymerase acidic protein E199K substitution in influenza A viruses on baloxavir susceptibility},
  author = {Emi Takashita and Yoshihiro Yasui and Asaka Ikegaya and Kyohei Saka and Noriyuki Maeshiro and Hiroko Morita and Shiho Nagata and Seiichiro Fujisaki and Hideka Miura and Noriko Kishida and Kazuya Nakamura and Masayuki Shirakura and Shinji Watanabe and Hideki Hasegawa and Kazuya Mitsuhashi and Asami Ohnishi and Tomoko Takahashi and Yuko Suzuki and Minako Ato and Youko Fujiya and Naomi Ogawa and Nozomi Saito and Miyako Kon and Ayari Ikeda and Asaka Okubo and Yuki Wakabayashi and Akira Wakatsuki and Rina Kubota and Yoshiyuki Makino and Yasuo Kaburagi and Hitomi Yahata and Tomofumi Seno and Mami Nagashima and Kohei Shimizu and Chie Akaboshi and Yumiko Nagasawa and Kaori Imura and Miho Kitazume and Michiko Takeuchi and Erina Miyajima and Isako Onoda and Hirosato Ehara and Ryota Akaike and Takahisa Shimada and Nao Kobashi and Nobushige Sakai and Masahiro Nishioka and Yusuke Sato and Masakazu Suzuki and Takuya Yano and Asa Tanino and Kazuko Nakagawa and Saeko Morikawa and Hideki Mizutani and Tomohiro Oshibe and Ai Mori and Saya Yamamoto and Shiho Nagase and Yutaka Ueda and Yurie Kanba and Manabu Ishii and Yukie Shimazu and Yasutsugu Kawahara and Mitsuhiro Kameyama and Mizuki Yamamoto and Yukari Tsuchida and Sayako Yoshida and Wataru Satou and Yuri Kondo and Michihiko Miyamoto and Sonoko Izumida and Ukyo Osoegawa and Yumika Takaki and Mayumi Kadoguchi and Minoru Ikeda and Nami Tsuru},
  year = {2025},
  journal = {Antiviral Research},
  doi = {10.1016/j.antiviral.2025.106173},
  url = {https://doi.org/10.1016/j.antiviral.2025.106173}
}

RIS

TY  - JOUR
TI  - Impact of the polymerase acidic protein E199K substitution in influenza A viruses on baloxavir susceptibility
AU  - Emi Takashita
AU  - Yoshihiro Yasui
AU  - Asaka Ikegaya
AU  - Kyohei Saka
AU  - Noriyuki Maeshiro
AU  - Hiroko Morita
AU  - Shiho Nagata
AU  - Seiichiro Fujisaki
AU  - Hideka Miura
AU  - Noriko Kishida
AU  - Kazuya Nakamura
AU  - Masayuki Shirakura
AU  - Shinji Watanabe
AU  - Hideki Hasegawa
AU  - Kazuya Mitsuhashi
AU  - Asami Ohnishi
AU  - Tomoko Takahashi
AU  - Yuko Suzuki
AU  - Minako Ato
AU  - Youko Fujiya
AU  - Naomi Ogawa
AU  - Nozomi Saito
AU  - Miyako Kon
AU  - Ayari Ikeda
AU  - Asaka Okubo
AU  - Yuki Wakabayashi
AU  - Akira Wakatsuki
AU  - Rina Kubota
AU  - Yoshiyuki Makino
AU  - Yasuo Kaburagi
AU  - Hitomi Yahata
AU  - Tomofumi Seno
AU  - Mami Nagashima
AU  - Kohei Shimizu
AU  - Chie Akaboshi
AU  - Yumiko Nagasawa
AU  - Kaori Imura
AU  - Miho Kitazume
AU  - Michiko Takeuchi
AU  - Erina Miyajima
AU  - Isako Onoda
AU  - Hirosato Ehara
AU  - Ryota Akaike
AU  - Takahisa Shimada
AU  - Nao Kobashi
AU  - Nobushige Sakai
AU  - Masahiro Nishioka
AU  - Yusuke Sato
AU  - Masakazu Suzuki
AU  - Takuya Yano
AU  - Asa Tanino
AU  - Kazuko Nakagawa
AU  - Saeko Morikawa
AU  - Hideki Mizutani
AU  - Tomohiro Oshibe
AU  - Ai Mori
AU  - Saya Yamamoto
AU  - Shiho Nagase
AU  - Yutaka Ueda
AU  - Yurie Kanba
AU  - Manabu Ishii
AU  - Yukie Shimazu
AU  - Yasutsugu Kawahara
AU  - Mitsuhiro Kameyama
AU  - Mizuki Yamamoto
AU  - Yukari Tsuchida
AU  - Sayako Yoshida
AU  - Wataru Satou
AU  - Yuri Kondo
AU  - Michihiko Miyamoto
AU  - Sonoko Izumida
AU  - Ukyo Osoegawa
AU  - Yumika Takaki
AU  - Mayumi Kadoguchi
AU  - Minoru Ikeda
AU  - Nami Tsuru
PY  - 2025
JO  - Antiviral Research
DO  - 10.1016/j.antiviral.2025.106173
UR  - https://doi.org/10.1016/j.antiviral.2025.106173
ER  -

APA

Takashita, E., Yasui, Y., Ikegaya, A., Saka, K., Maeshiro, N., Morita, H., Nagata, S., Fujisaki, S., Miura, H., Kishida, N., Nakamura, K., Shirakura, M., Watanabe, S., Hasegawa, H., Mitsuhashi, K., Ohnishi, A., Takahashi, T., Suzuki, Y., Ato, M., Fujiya, Y., Ogawa, N., Saito, N., Kon, M., Ikeda, A., Okubo, A., Wakabayashi, Y., Wakatsuki, A., Kubota, R., Makino, Y., Kaburagi, Y., Yahata, H., Seno, T., Nagashima, M., Shimizu, K., Akaboshi, C., Nagasawa, Y., Imura, K., Kitazume, M., Takeuchi, M., Miyajima, E., Onoda, I., Ehara, H., Akaike, R., Shimada, T., Kobashi, N., Sakai, N., Nishioka, M., Sato, Y., Suzuki, M., Yano, T., Tanino, A., Nakagawa, K., Morikawa, S., Mizutani, H., Oshibe, T., Mori, A., Yamamoto, S., Nagase, S., Ueda, Y., Kanba, Y., Ishii, M., Shimazu, Y., Kawahara, Y., Kameyama, M., Yamamoto, M., Tsuchida, Y., Yoshida, S., Satou, W., Kondo, Y., Miyamoto, M., Izumida, S., Osoegawa, U., Takaki, Y., Kadoguchi, M., Ikeda, M., & Tsuru, N. (2025). Impact of the polymerase acidic protein E199K substitution in influenza A viruses on baloxavir susceptibility. Antiviral Research. https://doi.org/10.1016/j.antiviral.2025.106173

Source records

crossref · retrieved 2026-09-26T17:18:38.327Z