Conceptual framework for the definition of disease modification in systemic sclerosis and potential implications for drug development and clinical study design

Jörg H.W. Distler, Shervin Assassi, Armando Gabrielli, Yannick Allanore, Lorinda Chung, Maurizio Cutolo, Francesco Del Galdo, Jeska K. De Vries-Bouwstra, Robyn T. Domsic, Muriel Elhai, Tracy Frech, Monique Hinchcliff, Bernhard Homey, Dinesh Khanna, Thomas Krieg, Masataka Kuwana, Alain Lescoat, Andrea H.L. Low, Marco Matucci-Cerinic, Zsuzsanna H. McMahan, Jerry A. Molitor, Luc Mouthon, Mandana Nikpour, Gabriela Riemekasten, Julia Spierings, Marie-Elise Truchetet, Vanessa Smith, John Varga, Elizabeth Volkmann, Madelon C. Vonk, Jiucun Wang, Dong Xu, Honglin Zhu, Anna-Maria Hoffmann-Vold, Christopher P. Denton, Oliver Distler

Open source

DOI
10.1016/j.ard.2026.08.006
Published
2026-09
Container
Annals of the Rheumatic Diseases
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/j.ard.2026.08.006,
  title = {Conceptual framework for the definition of disease modification in systemic sclerosis and potential implications for drug development and clinical study design},
  author = {Jörg H.W. Distler and Shervin Assassi and Armando Gabrielli and Yannick Allanore and Lorinda Chung and Maurizio Cutolo and Francesco Del Galdo and Jeska K. De Vries-Bouwstra and Robyn T. Domsic and Muriel Elhai and Tracy Frech and Monique Hinchcliff and Bernhard Homey and Dinesh Khanna and Thomas Krieg and Masataka Kuwana and Alain Lescoat and Andrea H.L. Low and Marco Matucci-Cerinic and Zsuzsanna H. McMahan and Jerry A. Molitor and Luc Mouthon and Mandana Nikpour and Gabriela Riemekasten and Julia Spierings and Marie-Elise Truchetet and Vanessa Smith and John Varga and Elizabeth Volkmann and Madelon C. Vonk and Jiucun Wang and Dong Xu and Honglin Zhu and Anna-Maria Hoffmann-Vold and Christopher P. Denton and Oliver Distler},
  year = {2026},
  journal = {Annals of the Rheumatic Diseases},
  doi = {10.1016/j.ard.2026.08.006},
  url = {https://doi.org/10.1016/j.ard.2026.08.006}
}

RIS

TY  - JOUR
TI  - Conceptual framework for the definition of disease modification in systemic sclerosis and potential implications for drug development and clinical study design
AU  - Jörg H.W. Distler
AU  - Shervin Assassi
AU  - Armando Gabrielli
AU  - Yannick Allanore
AU  - Lorinda Chung
AU  - Maurizio Cutolo
AU  - Francesco Del Galdo
AU  - Jeska K. De Vries-Bouwstra
AU  - Robyn T. Domsic
AU  - Muriel Elhai
AU  - Tracy Frech
AU  - Monique Hinchcliff
AU  - Bernhard Homey
AU  - Dinesh Khanna
AU  - Thomas Krieg
AU  - Masataka Kuwana
AU  - Alain Lescoat
AU  - Andrea H.L. Low
AU  - Marco Matucci-Cerinic
AU  - Zsuzsanna H. McMahan
AU  - Jerry A. Molitor
AU  - Luc Mouthon
AU  - Mandana Nikpour
AU  - Gabriela Riemekasten
AU  - Julia Spierings
AU  - Marie-Elise Truchetet
AU  - Vanessa Smith
AU  - John Varga
AU  - Elizabeth Volkmann
AU  - Madelon C. Vonk
AU  - Jiucun Wang
AU  - Dong Xu
AU  - Honglin Zhu
AU  - Anna-Maria Hoffmann-Vold
AU  - Christopher P. Denton
AU  - Oliver Distler
PY  - 2026
JO  - Annals of the Rheumatic Diseases
DO  - 10.1016/j.ard.2026.08.006
UR  - https://doi.org/10.1016/j.ard.2026.08.006
ER  - 

APA

Distler, J. H., Assassi, S., Gabrielli, A., Allanore, Y., Chung, L., Cutolo, M., Galdo, F. D., Vries-Bouwstra, J. K. D., Domsic, R. T., Elhai, M., Frech, T., Hinchcliff, M., Homey, B., Khanna, D., Krieg, T., Kuwana, M., Lescoat, A., Low, A. H., Matucci-Cerinic, M., McMahan, Z. H., Molitor, J. A., Mouthon, L., Nikpour, M., Riemekasten, G., Spierings, J., Truchetet, M., Smith, V., Varga, J., Volkmann, E., Vonk, M. C., Wang, J., Xu, D., Zhu, H., Hoffmann-Vold, A., Denton, C. P., & Distler, O. (2026). Conceptual framework for the definition of disease modification in systemic sclerosis and potential implications for drug development and clinical study design. Annals of the Rheumatic Diseases. https://doi.org/10.1016/j.ard.2026.08.006

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