Rationally designed quinazolinone derivatives incorporating acetyl pyridine and thiazole scaffolds as dual EGFR/HER-2 anticancer agents: integrated biological evaluation, molecular profiling, and advanced computational studies

Hagar S. El-Hema, Rasha A.-S. El-Ghorab, Mohamed A. Hawata, Eman S. Nossier, Modather F. Hussein, Ahmed T. Elhendawy, Mohammed F. Hamza, Adel A.-H. Abdel-Rahman

Open source

DOI
10.1016/j.bioorg.2026.110052
Published
2026-09
Container
Bioorganic Chemistry
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/j.bioorg.2026.110052,
  title = {Rationally designed quinazolinone derivatives incorporating acetyl pyridine and thiazole scaffolds as dual EGFR/HER-2 anticancer agents: integrated biological evaluation, molecular profiling, and advanced computational studies},
  author = {Hagar S. El-Hema and Rasha A.-S. El-Ghorab and Mohamed A. Hawata and Eman S. Nossier and Modather F. Hussein and Ahmed T. Elhendawy and Mohammed F. Hamza and Adel A.-H. Abdel-Rahman},
  year = {2026},
  journal = {Bioorganic Chemistry},
  doi = {10.1016/j.bioorg.2026.110052},
  url = {https://doi.org/10.1016/j.bioorg.2026.110052}
}

RIS

TY  - JOUR
TI  - Rationally designed quinazolinone derivatives incorporating acetyl pyridine and thiazole scaffolds as dual EGFR/HER-2 anticancer agents: integrated biological evaluation, molecular profiling, and advanced computational studies
AU  - Hagar S. El-Hema
AU  - Rasha A.-S. El-Ghorab
AU  - Mohamed A. Hawata
AU  - Eman S. Nossier
AU  - Modather F. Hussein
AU  - Ahmed T. Elhendawy
AU  - Mohammed F. Hamza
AU  - Adel A.-H. Abdel-Rahman
PY  - 2026
JO  - Bioorganic Chemistry
DO  - 10.1016/j.bioorg.2026.110052
UR  - https://doi.org/10.1016/j.bioorg.2026.110052
ER  - 

APA

El-Hema, H. S., El-Ghorab, R. A., Hawata, M. A., Nossier, E. S., Hussein, M. F., Elhendawy, A. T., Hamza, M. F., & Abdel-Rahman, A. A. (2026). Rationally designed quinazolinone derivatives incorporating acetyl pyridine and thiazole scaffolds as dual EGFR/HER-2 anticancer agents: integrated biological evaluation, molecular profiling, and advanced computational studies. Bioorganic Chemistry. https://doi.org/10.1016/j.bioorg.2026.110052

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