Design, synthesis, and biological evaluation of novel 1-aryl-3-hydroxypyrrolidine derivatives as dual HGK/HPK1 inhibitors with therapeutic potential for lung cancer.

Liu S, Ma J, Li Y, Yang J, Zhang D, Cai N, Tan Z, Zhai X

Open source

DOI
10.1016/j.bioorg.2026.110473
Published
2026 Sep 6
Container
Bioorganic chemistry
Publisher
Not recorded
Open access
unknown

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BibTeX

@article{allodium:10.1016/j.bioorg.2026.110473,
  title = {Design, synthesis, and biological evaluation of novel 1-aryl-3-hydroxypyrrolidine derivatives as dual HGK/HPK1 inhibitors with therapeutic potential for lung cancer.},
  author = {Liu S and Ma J and Li Y and Yang J and Zhang D and Cai N and Tan Z and Zhai X},
  year = {2026},
  journal = {Bioorganic chemistry},
  doi = {10.1016/j.bioorg.2026.110473},
  url = {https://doi.org/10.1016/j.bioorg.2026.110473}
}

RIS

TY  - JOUR
TI  - Design, synthesis, and biological evaluation of novel 1-aryl-3-hydroxypyrrolidine derivatives as dual HGK/HPK1 inhibitors with therapeutic potential for lung cancer.
AU  - Liu S
AU  - Ma J
AU  - Li Y
AU  - Yang J
AU  - Zhang D
AU  - Cai N
AU  - Tan Z
AU  - Zhai X
PY  - 2026
JO  - Bioorganic chemistry
DO  - 10.1016/j.bioorg.2026.110473
UR  - https://doi.org/10.1016/j.bioorg.2026.110473
ER  - 

APA

S, L., J, M., Y, L., J, Y., D, Z., N, C., Z, T., & X, Z. (2026). Design, synthesis, and biological evaluation of novel 1-aryl-3-hydroxypyrrolidine derivatives as dual HGK/HPK1 inhibitors with therapeutic potential for lung cancer.. Bioorganic chemistry. https://doi.org/10.1016/j.bioorg.2026.110473

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