Rational design of hybrid hydrazide–hydrazone/thiourea derivatives as potential VEGFR-2 targeting anticancer agents: synthesis, biological evaluation, and mechanistic insights into anticancer activity

Guzide Satir-Basaran, Ahmed Amleh, Antonio Curcio, Marina Bilotta, Nuh Mehmet Kararenk, Melisa Albayrak, Elçin Bakır, Akman Emre Çatak, Amir Ashoorzadeh, Stefano Alcaro, M. İhsan Han

Open source

DOI
10.1016/j.bioorg.2026.110531
Published
2026-10
Container
Bioorganic Chemistry
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/j.bioorg.2026.110531,
  title = {Rational design of hybrid hydrazide–hydrazone/thiourea derivatives as potential VEGFR-2 targeting anticancer agents: synthesis, biological evaluation, and mechanistic insights into anticancer activity},
  author = {Guzide Satir-Basaran and Ahmed Amleh and Antonio Curcio and Marina Bilotta and Nuh Mehmet Kararenk and Melisa Albayrak and Elçin Bakır and Akman Emre Çatak and Amir Ashoorzadeh and Stefano Alcaro and M. İhsan Han},
  year = {2026},
  journal = {Bioorganic Chemistry},
  doi = {10.1016/j.bioorg.2026.110531},
  url = {https://doi.org/10.1016/j.bioorg.2026.110531}
}

RIS

TY  - JOUR
TI  - Rational design of hybrid hydrazide–hydrazone/thiourea derivatives as potential VEGFR-2 targeting anticancer agents: synthesis, biological evaluation, and mechanistic insights into anticancer activity
AU  - Guzide Satir-Basaran
AU  - Ahmed Amleh
AU  - Antonio Curcio
AU  - Marina Bilotta
AU  - Nuh Mehmet Kararenk
AU  - Melisa Albayrak
AU  - Elçin Bakır
AU  - Akman Emre Çatak
AU  - Amir Ashoorzadeh
AU  - Stefano Alcaro
AU  - M. İhsan Han
PY  - 2026
JO  - Bioorganic Chemistry
DO  - 10.1016/j.bioorg.2026.110531
UR  - https://doi.org/10.1016/j.bioorg.2026.110531
ER  - 

APA

Satir-Basaran, G., Amleh, A., Curcio, A., Bilotta, M., Kararenk, N. M., Albayrak, M., Bakır, E., Çatak, A. E., Ashoorzadeh, A., Alcaro, S., & Han, M. İ. (2026). Rational design of hybrid hydrazide–hydrazone/thiourea derivatives as potential VEGFR-2 targeting anticancer agents: synthesis, biological evaluation, and mechanistic insights into anticancer activity. Bioorganic Chemistry. https://doi.org/10.1016/j.bioorg.2026.110531

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