Design, synthesis, and molecular modeling of quinoline-linked diphenylpyrazoles as multitarget EGFR, VEGFR-2, and COX-2 inhibitors with anticancer, anti-inflammatory and apoptosis-inducing properties.

Hamdi A, Elnagar MR, Hussein MS, El-Sayed NNE, Serag MI, El-Azab AS, Brogi S, Ghabbour HA, Nawareg NA, El-Shafey HW, Abdel-Aziz AA

Open source

DOI
10.1016/j.bioorg.2026.110574
Published
2026 Sep 24
Container
Bioorganic chemistry
Publisher
Not recorded
Open access
unknown

Credibility signals

limited evidence Score 43/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1016/j.bioorg.2026.110574,
  title = {Design, synthesis, and molecular modeling of quinoline-linked diphenylpyrazoles as multitarget EGFR, VEGFR-2, and COX-2 inhibitors with anticancer, anti-inflammatory and apoptosis-inducing properties.},
  author = {Hamdi A and Elnagar MR and Hussein MS and El-Sayed NNE and Serag MI and El-Azab AS and Brogi S and Ghabbour HA and Nawareg NA and El-Shafey HW and Abdel-Aziz AA},
  year = {2026},
  journal = {Bioorganic chemistry},
  doi = {10.1016/j.bioorg.2026.110574},
  url = {https://doi.org/10.1016/j.bioorg.2026.110574}
}

RIS

TY  - JOUR
TI  - Design, synthesis, and molecular modeling of quinoline-linked diphenylpyrazoles as multitarget EGFR, VEGFR-2, and COX-2 inhibitors with anticancer, anti-inflammatory and apoptosis-inducing properties.
AU  - Hamdi A
AU  - Elnagar MR
AU  - Hussein MS
AU  - El-Sayed NNE
AU  - Serag MI
AU  - El-Azab AS
AU  - Brogi S
AU  - Ghabbour HA
AU  - Nawareg NA
AU  - El-Shafey HW
AU  - Abdel-Aziz AA
PY  - 2026
JO  - Bioorganic chemistry
DO  - 10.1016/j.bioorg.2026.110574
UR  - https://doi.org/10.1016/j.bioorg.2026.110574
ER  - 

APA

A, H., MR, E., MS, H., NNE, E., MI, S., AS, E., S, B., HA, G., NA, N., HW, E., & AA, A. (2026). Design, synthesis, and molecular modeling of quinoline-linked diphenylpyrazoles as multitarget EGFR, VEGFR-2, and COX-2 inhibitors with anticancer, anti-inflammatory and apoptosis-inducing properties.. Bioorganic chemistry. https://doi.org/10.1016/j.bioorg.2026.110574

Source records