Cardiotoxicity of trametinib monotherapy in adults with neurofibromatosis type 1: Results from the TRAIN study.

Ditta SA, Noordhoek DC, Jongbloed F, Oomen-de Hoop E, Meijers WC, Van den Bent MJ, Bos MEMM, Mathijssen RHJ, Taal W, Manintveld OC

Open source

DOI: 10.1016/j.biopha.2026.119251
Published: 2026 May
Container: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Publisher: Not recorded
Open access: unknown

Credibility signals

limited evidence Score 43/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1016/j.biopha.2026.119251,
  title = {Cardiotoxicity of trametinib monotherapy in adults with neurofibromatosis type 1: Results from the TRAIN study.},
  author = {Ditta SA and Noordhoek DC and Jongbloed F and Oomen-de Hoop E and Meijers WC and Van den Bent MJ and Bos MEMM and Mathijssen RHJ and Taal W and Manintveld OC},
  year = {2026},
  journal = {Biomedicine \& pharmacotherapy = Biomedecine \& pharmacotherapie},
  doi = {10.1016/j.biopha.2026.119251},
  url = {https://doi.org/10.1016/j.biopha.2026.119251}
}

RIS

TY  - JOUR
TI  - Cardiotoxicity of trametinib monotherapy in adults with neurofibromatosis type 1: Results from the TRAIN study.
AU  - Ditta SA
AU  - Noordhoek DC
AU  - Jongbloed F
AU  - Oomen-de Hoop E
AU  - Meijers WC
AU  - Van den Bent MJ
AU  - Bos MEMM
AU  - Mathijssen RHJ
AU  - Taal W
AU  - Manintveld OC
PY  - 2026
JO  - Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
DO  - 10.1016/j.biopha.2026.119251
UR  - https://doi.org/10.1016/j.biopha.2026.119251
ER  -

APA

SA, D., DC, N., F, J., E, O. H., WC, M., MJ, V. D. B., MEMM, B., RHJ, M., W, T., & OC, M. (2026). Cardiotoxicity of trametinib monotherapy in adults with neurofibromatosis type 1: Results from the TRAIN study.. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. https://doi.org/10.1016/j.biopha.2026.119251

Source records

pubmed · retrieved 2026-09-25T22:28:19.156Z