Trametinib-mediated MEK inhibition impairs cancer cell viability and invasion in patient-derived tumor avatars of glioblastoma with extraneural metastases: A proof-of-concept study

Metka Novak, Bernarda Majc, Marija Skoblar Vidmar, Špela Kladnik, Tina Kolenc Milavec, Anamarija Habič, Simona Katrin Galun, Pia Žižek, Andrej Porčnik, Alenka Matjašič, Andrej Zupan, Miha Jerala, Matic Bošnjak, Borut Prestor, Barbara Breznik Vittori

Open source

DOI
10.1016/j.biopha.2026.119832
Published
2026-09
Container
Biomedicine & Pharmacotherapy
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/j.biopha.2026.119832,
  title = {Trametinib-mediated MEK inhibition impairs cancer cell viability and invasion in patient-derived tumor avatars of glioblastoma with extraneural metastases: A proof-of-concept study},
  author = {Metka Novak and Bernarda Majc and Marija Skoblar Vidmar and Špela Kladnik and Tina Kolenc Milavec and Anamarija Habič and Simona Katrin Galun and Pia Žižek and Andrej Porčnik and Alenka Matjašič and Andrej Zupan and Miha Jerala and Matic Bošnjak and Borut Prestor and Barbara Breznik Vittori},
  year = {2026},
  journal = {Biomedicine \& Pharmacotherapy},
  doi = {10.1016/j.biopha.2026.119832},
  url = {https://doi.org/10.1016/j.biopha.2026.119832}
}

RIS

TY  - JOUR
TI  - Trametinib-mediated MEK inhibition impairs cancer cell viability and invasion in patient-derived tumor avatars of glioblastoma with extraneural metastases: A proof-of-concept study
AU  - Metka Novak
AU  - Bernarda Majc
AU  - Marija Skoblar Vidmar
AU  - Špela Kladnik
AU  - Tina Kolenc Milavec
AU  - Anamarija Habič
AU  - Simona Katrin Galun
AU  - Pia Žižek
AU  - Andrej Porčnik
AU  - Alenka Matjašič
AU  - Andrej Zupan
AU  - Miha Jerala
AU  - Matic Bošnjak
AU  - Borut Prestor
AU  - Barbara Breznik Vittori
PY  - 2026
JO  - Biomedicine & Pharmacotherapy
DO  - 10.1016/j.biopha.2026.119832
UR  - https://doi.org/10.1016/j.biopha.2026.119832
ER  - 

APA

Novak, M., Majc, B., Vidmar, M. S., Kladnik, Š., Milavec, T. K., Habič, A., Galun, S. K., Žižek, P., Porčnik, A., Matjašič, A., Zupan, A., Jerala, M., Bošnjak, M., Prestor, B., & Vittori, B. B. (2026). Trametinib-mediated MEK inhibition impairs cancer cell viability and invasion in patient-derived tumor avatars of glioblastoma with extraneural metastases: A proof-of-concept study. Biomedicine & Pharmacotherapy. https://doi.org/10.1016/j.biopha.2026.119832

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