Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use

David M. Brazel, Yu Jiang, Jordan M. Hughey, Valérie Turcot, Xiaowei Zhan, Jian Gong, Chiara Batini, J. Dylan Weissenkampen, MengZhen Liu, Daniel R. Barnes, Sarah Bertelsen, Yi-Ling Chou, A. Mesut Erzurumluoglu, Jessica D. Faul, Jeff Haessler, Anke R. Hammerschlag, Chris Hsu, Manav Kapoor, Dongbing Lai, Nhung Le, Christiaan A. de Leeuw, Anu Loukola, Massimo Mangino, Carl A. Melbourne, Giorgio Pistis, Beenish Qaiser, Rebecca Rohde, Yaming Shao, Heather Stringham, Leah Wetherill, Wei Zhao, Arpana Agrawal, Laura Bierut, Chu Chen, Charles B. Eaton, Alison Goate, Christopher Haiman, Andrew Heath, William G. Iacono, Nicholas G. Martin, Tinca J. Polderman, Alex Reiner, John Rice, David Schlessinger, H. Steven Scholte, Jennifer A. Smith, Jean-Claude Tardif, Hilary A. Tindle, Andries R. van der Leij, Michael Boehnke, Jenny Chang-Claude, Francesco Cucca, Sean P. David, Tatiana Foroud, Joanna M.M. Howson, Sharon L.R. Kardia, Charles Kooperberg, Markku Laakso, Guillaume Lettre, Pamela Madden, Matt McGue, Kari North, Danielle Posthuma, Timothy Spector, Daniel Stram, Martin D. Tobin, David R. Weir, Jaakko Kaprio, Gonçalo R. Abecasis, Dajiang J. Liu, Scott Vrieze, Praveen Surendran, Robin Young, Daniel R. Barnes, Sune Fallgaard Nielsen, Asif Rasheed, Maria Samuel, Wei Zhao, Jukka Kontto, Markus Perola, Muriel Caslake, Anton J.M. de Craen, Stella Trompet, Maria Uria-Nickelsen, Anders Malarstig, Dermot F. Reily, Maarten Hoek, Thomas Vogt, J. Wouter Jukema, Naveed Sattar, Ian Ford, Chris J. Packard, Dewan S. Alam, Abdulla al Shafi Majumder, Emanuele Di Angelantonio, Rajiv Chowdhury, Philippe Amouyel, Dominique Arveiler, Stefan Blankenberg, Jean Ferrières, Frank Kee, Kari Kuulasmaa, Martina Müller-Nurasyid, Giovanni Veronesi, Jarmo Virtamo, EPIC-CVD Consortium, Philippe Frossard, Børge Grønne Nordestgaard, Danish Saleheen, John Danesh, Adam S. Butterworth, Joanna M.M. Howson, A. Mesut Erzurumluoglu, Victoria E. Jackson, Carl A. Melbourne, Tibor V. Varga, Helen R. Warren, Vinicius Tragante, Ioanna Tachmazidou, Sarah E. Harris, Evangelos Evangelou, Jonathan Marten, Weihua Zhang, Elisabeth Altmaier, Jian’an Luan, Claudia Langenberg, Robert A. Scott, Hanieh Yaghootkar, Kathleen Stirrups, Stavroula Kanoni, Eirini Marouli, Fredrik Karpe, Anna F. Dominiczak, Peter Sever, Neil Poulter, Olov Rolandsson, Clemens Baumbach, Saima Afaq, John C. Chambers, Jaspal S. Kooner, Nicholas J. Wareham, Frida Renström, Göran Hallmans, Riccardo E. Marioni, Janie Corley, John M. Starr, Niek Verweij, Rudolf A. de Boer, Peter van der Meer, Ersin Yavas, Ilonca Vaartjes, Michiel L. Bots, Folkert W. Asselbergs, Hans J. Grabe, Henry Völzke, Matthias Nauck, Stefan Weiss, Paul D.P. Pharoah, Alison M. Dunning, Joe G. Dennis, Deborah J. Thompson, Kyriaki Michailidou, Douglas F. Easton, Antonis C. Antoniou, Jessica Tyrrell, Evelin Mihailov, Nilesh J. Samani, Kaixin Zhou, Matthew J. Neville, Andres Metspalu, Colin N.A. Palmer, Ian P. Hall, David P. Strachan, Ian J. Deary, Tim M. Frayling, Caroline Hayward, Pim van der Harst, Eleftheria Zeggini, Understanding Society Scientific Group, Patricia B. Munroe, Jan-Håkan Jansson, Paul W. Franks, Panos Deloukas, Mark J. Caulfield, Louise V. Wain, Martin D. Tobin

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DOI
10.1016/j.biopsych.2018.11.024
Published
2019-06
Container
Biological Psychiatry
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/j.biopsych.2018.11.024,
  title = {Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use},
  author = {David M. Brazel and Yu Jiang and Jordan M. Hughey and Valérie Turcot and Xiaowei Zhan and Jian Gong and Chiara Batini and J. Dylan Weissenkampen and MengZhen Liu and Daniel R. Barnes and Sarah Bertelsen and Yi-Ling Chou and A. Mesut Erzurumluoglu and Jessica D. Faul and Jeff Haessler and Anke R. Hammerschlag and Chris Hsu and Manav Kapoor and Dongbing Lai and Nhung Le and Christiaan A. de Leeuw and Anu Loukola and Massimo Mangino and Carl A. Melbourne and Giorgio Pistis and Beenish Qaiser and Rebecca Rohde and Yaming Shao and Heather Stringham and Leah Wetherill and Wei Zhao and Arpana Agrawal and Laura Bierut and Chu Chen and Charles B. Eaton and Alison Goate and Christopher Haiman and Andrew Heath and William G. Iacono and Nicholas G. Martin and Tinca J. Polderman and Alex Reiner and John Rice and David Schlessinger and H. Steven Scholte and Jennifer A. Smith and Jean-Claude Tardif and Hilary A. Tindle and Andries R. van der Leij and Michael Boehnke and Jenny Chang-Claude and Francesco Cucca and Sean P. David and Tatiana Foroud and Joanna M.M. Howson and Sharon L.R. Kardia and Charles Kooperberg and Markku Laakso and Guillaume Lettre and Pamela Madden and Matt McGue and Kari North and Danielle Posthuma and Timothy Spector and Daniel Stram and Martin D. Tobin and David R. Weir and Jaakko Kaprio and Gonçalo R. Abecasis and Dajiang J. Liu and Scott Vrieze and Praveen Surendran and Robin Young and Daniel R. Barnes and Sune Fallgaard Nielsen and Asif Rasheed and Maria Samuel and Wei Zhao and Jukka Kontto and Markus Perola and Muriel Caslake and Anton J.M. de Craen and Stella Trompet and Maria Uria-Nickelsen and Anders Malarstig and Dermot F. Reily and Maarten Hoek and Thomas Vogt and J. Wouter Jukema and Naveed Sattar and Ian Ford and Chris J. Packard and Dewan S. Alam and Abdulla al Shafi Majumder and Emanuele Di Angelantonio and Rajiv Chowdhury and Philippe Amouyel and Dominique Arveiler and Stefan Blankenberg and Jean Ferrières and Frank Kee and Kari Kuulasmaa and Martina Müller-Nurasyid and Giovanni Veronesi and Jarmo Virtamo and EPIC-CVD Consortium and Philippe Frossard and Børge Grønne Nordestgaard and Danish Saleheen and John Danesh and Adam S. Butterworth and Joanna M.M. Howson and A. Mesut Erzurumluoglu and Victoria E. Jackson and Carl A. Melbourne and Tibor V. Varga and Helen R. Warren and Vinicius Tragante and Ioanna Tachmazidou and Sarah E. Harris and Evangelos Evangelou and Jonathan Marten and Weihua Zhang and Elisabeth Altmaier and Jian’an Luan and Claudia Langenberg and Robert A. Scott and Hanieh Yaghootkar and Kathleen Stirrups and Stavroula Kanoni and Eirini Marouli and Fredrik Karpe and Anna F. Dominiczak and Peter Sever and Neil Poulter and Olov Rolandsson and Clemens Baumbach and Saima Afaq and John C. Chambers and Jaspal S. Kooner and Nicholas J. Wareham and Frida Renström and Göran Hallmans and Riccardo E. Marioni and Janie Corley and John M. Starr and Niek Verweij and Rudolf A. de Boer and Peter van der Meer and Ersin Yavas and Ilonca Vaartjes and Michiel L. Bots and Folkert W. Asselbergs and Hans J. Grabe and Henry Völzke and Matthias Nauck and Stefan Weiss and Paul D.P. Pharoah and Alison M. Dunning and Joe G. Dennis and Deborah J. Thompson and Kyriaki Michailidou and Douglas F. Easton and Antonis C. Antoniou and Jessica Tyrrell and Evelin Mihailov and Nilesh J. Samani and Kaixin Zhou and Matthew J. Neville and Andres Metspalu and Colin N.A. Palmer and Ian P. Hall and David P. Strachan and Ian J. Deary and Tim M. Frayling and Caroline Hayward and Pim van der Harst and Eleftheria Zeggini and Understanding Society Scientific Group and Patricia B. Munroe and Jan-Håkan Jansson and Paul W. Franks and Panos Deloukas and Mark J. Caulfield and Louise V. Wain and Martin D. Tobin},
  year = {2019},
  journal = {Biological Psychiatry},
  doi = {10.1016/j.biopsych.2018.11.024},
  url = {https://doi.org/10.1016/j.biopsych.2018.11.024}
}

RIS

TY  - JOUR
TI  - Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use
AU  - David M. Brazel
AU  - Yu Jiang
AU  - Jordan M. Hughey
AU  - Valérie Turcot
AU  - Xiaowei Zhan
AU  - Jian Gong
AU  - Chiara Batini
AU  - J. Dylan Weissenkampen
AU  - MengZhen Liu
AU  - Daniel R. Barnes
AU  - Sarah Bertelsen
AU  - Yi-Ling Chou
AU  - A. Mesut Erzurumluoglu
AU  - Jessica D. Faul
AU  - Jeff Haessler
AU  - Anke R. Hammerschlag
AU  - Chris Hsu
AU  - Manav Kapoor
AU  - Dongbing Lai
AU  - Nhung Le
AU  - Christiaan A. de Leeuw
AU  - Anu Loukola
AU  - Massimo Mangino
AU  - Carl A. Melbourne
AU  - Giorgio Pistis
AU  - Beenish Qaiser
AU  - Rebecca Rohde
AU  - Yaming Shao
AU  - Heather Stringham
AU  - Leah Wetherill
AU  - Wei Zhao
AU  - Arpana Agrawal
AU  - Laura Bierut
AU  - Chu Chen
AU  - Charles B. Eaton
AU  - Alison Goate
AU  - Christopher Haiman
AU  - Andrew Heath
AU  - William G. Iacono
AU  - Nicholas G. Martin
AU  - Tinca J. Polderman
AU  - Alex Reiner
AU  - John Rice
AU  - David Schlessinger
AU  - H. Steven Scholte
AU  - Jennifer A. Smith
AU  - Jean-Claude Tardif
AU  - Hilary A. Tindle
AU  - Andries R. van der Leij
AU  - Michael Boehnke
AU  - Jenny Chang-Claude
AU  - Francesco Cucca
AU  - Sean P. David
AU  - Tatiana Foroud
AU  - Joanna M.M. Howson
AU  - Sharon L.R. Kardia
AU  - Charles Kooperberg
AU  - Markku Laakso
AU  - Guillaume Lettre
AU  - Pamela Madden
AU  - Matt McGue
AU  - Kari North
AU  - Danielle Posthuma
AU  - Timothy Spector
AU  - Daniel Stram
AU  - Martin D. Tobin
AU  - David R. Weir
AU  - Jaakko Kaprio
AU  - Gonçalo R. Abecasis
AU  - Dajiang J. Liu
AU  - Scott Vrieze
AU  - Praveen Surendran
AU  - Robin Young
AU  - Daniel R. Barnes
AU  - Sune Fallgaard Nielsen
AU  - Asif Rasheed
AU  - Maria Samuel
AU  - Wei Zhao
AU  - Jukka Kontto
AU  - Markus Perola
AU  - Muriel Caslake
AU  - Anton J.M. de Craen
AU  - Stella Trompet
AU  - Maria Uria-Nickelsen
AU  - Anders Malarstig
AU  - Dermot F. Reily
AU  - Maarten Hoek
AU  - Thomas Vogt
AU  - J. Wouter Jukema
AU  - Naveed Sattar
AU  - Ian Ford
AU  - Chris J. Packard
AU  - Dewan S. Alam
AU  - Abdulla al Shafi Majumder
AU  - Emanuele Di Angelantonio
AU  - Rajiv Chowdhury
AU  - Philippe Amouyel
AU  - Dominique Arveiler
AU  - Stefan Blankenberg
AU  - Jean Ferrières
AU  - Frank Kee
AU  - Kari Kuulasmaa
AU  - Martina Müller-Nurasyid
AU  - Giovanni Veronesi
AU  - Jarmo Virtamo
AU  - EPIC-CVD Consortium
AU  - Philippe Frossard
AU  - Børge Grønne Nordestgaard
AU  - Danish Saleheen
AU  - John Danesh
AU  - Adam S. Butterworth
AU  - Joanna M.M. Howson
AU  - A. Mesut Erzurumluoglu
AU  - Victoria E. Jackson
AU  - Carl A. Melbourne
AU  - Tibor V. Varga
AU  - Helen R. Warren
AU  - Vinicius Tragante
AU  - Ioanna Tachmazidou
AU  - Sarah E. Harris
AU  - Evangelos Evangelou
AU  - Jonathan Marten
AU  - Weihua Zhang
AU  - Elisabeth Altmaier
AU  - Jian’an Luan
AU  - Claudia Langenberg
AU  - Robert A. Scott
AU  - Hanieh Yaghootkar
AU  - Kathleen Stirrups
AU  - Stavroula Kanoni
AU  - Eirini Marouli
AU  - Fredrik Karpe
AU  - Anna F. Dominiczak
AU  - Peter Sever
AU  - Neil Poulter
AU  - Olov Rolandsson
AU  - Clemens Baumbach
AU  - Saima Afaq
AU  - John C. Chambers
AU  - Jaspal S. Kooner
AU  - Nicholas J. Wareham
AU  - Frida Renström
AU  - Göran Hallmans
AU  - Riccardo E. Marioni
AU  - Janie Corley
AU  - John M. Starr
AU  - Niek Verweij
AU  - Rudolf A. de Boer
AU  - Peter van der Meer
AU  - Ersin Yavas
AU  - Ilonca Vaartjes
AU  - Michiel L. Bots
AU  - Folkert W. Asselbergs
AU  - Hans J. Grabe
AU  - Henry Völzke
AU  - Matthias Nauck
AU  - Stefan Weiss
AU  - Paul D.P. Pharoah
AU  - Alison M. Dunning
AU  - Joe G. Dennis
AU  - Deborah J. Thompson
AU  - Kyriaki Michailidou
AU  - Douglas F. Easton
AU  - Antonis C. Antoniou
AU  - Jessica Tyrrell
AU  - Evelin Mihailov
AU  - Nilesh J. Samani
AU  - Kaixin Zhou
AU  - Matthew J. Neville
AU  - Andres Metspalu
AU  - Colin N.A. Palmer
AU  - Ian P. Hall
AU  - David P. Strachan
AU  - Ian J. Deary
AU  - Tim M. Frayling
AU  - Caroline Hayward
AU  - Pim van der Harst
AU  - Eleftheria Zeggini
AU  - Understanding Society Scientific Group
AU  - Patricia B. Munroe
AU  - Jan-Håkan Jansson
AU  - Paul W. Franks
AU  - Panos Deloukas
AU  - Mark J. Caulfield
AU  - Louise V. Wain
AU  - Martin D. Tobin
PY  - 2019
JO  - Biological Psychiatry
DO  - 10.1016/j.biopsych.2018.11.024
UR  - https://doi.org/10.1016/j.biopsych.2018.11.024
ER  -

APA

Brazel, D. M., Jiang, Y., Hughey, J. M., Turcot, V., Zhan, X., Gong, J., Batini, C., Weissenkampen, J. D., Liu, M., Barnes, D. R., Bertelsen, S., Chou, Y., Erzurumluoglu, A. M., Faul, J. D., Haessler, J., Hammerschlag, A. R., Hsu, C., Kapoor, M., Lai, D., Le, N., Leeuw, C. A. D., Loukola, A., Mangino, M., Melbourne, C. A., Pistis, G., Qaiser, B., Rohde, R., Shao, Y., Stringham, H., Wetherill, L., Zhao, W., Agrawal, A., Bierut, L., Chen, C., Eaton, C. B., Goate, A., Haiman, C., Heath, A., Iacono, W. G., Martin, N. G., Polderman, T. J., Reiner, A., Rice, J., Schlessinger, D., Scholte, H. S., Smith, J. A., Tardif, J., Tindle, H. A., Leij, A. R. V. D., Boehnke, M., Chang-Claude, J., Cucca, F., David, S. P., Foroud, T., Howson, J. M., Kardia, S. L., Kooperberg, C., Laakso, M., Lettre, G., Madden, P., McGue, M., North, K., Posthuma, D., Spector, T., Stram, D., Tobin, M. D., Weir, D. R., Kaprio, J., Abecasis, G. R., Liu, D. J., Vrieze, S., Surendran, P., Young, R., Barnes, D. R., Nielsen, S. F., Rasheed, A., Samuel, M., Zhao, W., Kontto, J., Perola, M., Caslake, M., Craen, A. J. D., Trompet, S., Uria-Nickelsen, M., Malarstig, A., Reily, D. F., Hoek, M., Vogt, T., Jukema, J. W., Sattar, N., Ford, I., Packard, C. J., Alam, D. S., Majumder, A. A. S., Angelantonio, E. D., Chowdhury, R., Amouyel, P., Arveiler, D., Blankenberg, S., Ferrières, J., Kee, F., Kuulasmaa, K., Müller-Nurasyid, M., Veronesi, G., Virtamo, J., Consortium, E., Frossard, P., Nordestgaard, B. G., Saleheen, D., Danesh, J., Butterworth, A. S., Howson, J. M., Erzurumluoglu, A. M., Jackson, V. E., Melbourne, C. A., Varga, T. V., Warren, H. R., Tragante, V., Tachmazidou, I., Harris, S. E., Evangelou, E., Marten, J., Zhang, W., Altmaier, E., Luan, J., Langenberg, C., Scott, R. A., Yaghootkar, H., Stirrups, K., Kanoni, S., Marouli, E., Karpe, F., Dominiczak, A. F., Sever, P., Poulter, N., Rolandsson, O., Baumbach, C., Afaq, S., Chambers, J. C., Kooner, J. S., Wareham, N. J., Renström, F., Hallmans, G., Marioni, R. E., Corley, J., Starr, J. M., Verweij, N., Boer, R. A. D., Meer, P. V. D., Yavas, E., Vaartjes, I., Bots, M. L., Asselbergs, F. W., Grabe, H. J., Völzke, H., Nauck, M., Weiss, S., Pharoah, P. D., Dunning, A. M., Dennis, J. G., Thompson, D. J., Michailidou, K., Easton, D. F., Antoniou, A. C., Tyrrell, J., Mihailov, E., Samani, N. J., Zhou, K., Neville, M. J., Metspalu, A., Palmer, C. N., Hall, I. P., Strachan, D. P., Deary, I. J., Frayling, T. M., Hayward, C., Harst, P. V. D., Zeggini, E., Group, U. S. S., Munroe, P. B., Jansson, J., Franks, P. W., Deloukas, P., Caulfield, M. J., Wain, L. V., & Tobin, M. D. (2019). Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Biological Psychiatry. https://doi.org/10.1016/j.biopsych.2018.11.024

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