Shared and Distinct Alterations in Brain Structure of Youth With Internalizing or Externalizing Disorders: Findings From the ENIGMA Antisocial Behavior, ADHD, Major Depressive Disorder, and Anxiety Working Groups

Sophie Townend, Marlene Staginnus, Yidian Gao, Nina Alexander, Volker Arolt, Tobias Banaschewski, Katja Beesdo-Baum, Mark A. Bellgrove, Vivek Benegal, Robert J. Blair, Laura Blanco-Hinojo, Ole Jonas Boeken, Joscha Böhnlein, Sven Bölte, Linda M. Bonnekoh, Daniel Brandeis, Rodrigo A. Bressan, Fabian Breuer, Willem B. Bruin, Jan K. Buitelaar, Katie L. Burkhouse, Monica E. Calkins, Marta Cano, Narcis Cardoner, Hui Chen, Xianliang Chen, David R. Coghill, Olivier F. Colins, Colm G. Connolly, Michael C. Craig, Kathryn R. Cullen, Udo Dannlowski, Christopher G. Davey, Andrea Dietrich, Daifeng Dong, Christine M. Freitag, Thomas Frodl, Liesbet Goossens, Dominik Grotegerd, Raquel E. Gur, Ruben C. Gur, Jan Haavik, Cindy C. Hagan, Tim Hahn, Alfons O. Hamm, Ben J. Harrison, Catharina A. Hartman, Martin J. Herrmann, Tiffany C. Ho, Pieter J. Hoekstra, Bharath Holla, Karim Ibrahim, Andrea Jackowski, Hamidreza Jamalabadi, Yali Jiang, Tilo Kircher, Kerstin Konrad, Anna Kraus, Jonna Kuntsi, Till Langhammer, Luisa Lazaro, Elisabeth J. Leehr, Ulrike Lueken, Ren Ma, Frank P. MacMaster, Gisele G. Manfro, Anne Martinelli, Hannah Meinert, Susanne Meinert, Jarosław M. Michałowski, Qingsen Ming, Robert Moeck, Markus Muehlhan, Lilianne R. Mujica-Parodi, Benson Mwangi, Janina Neufeld, Joel T. Nigg, Ruth L. O’Gorman Tuura, Hyuntaek Oh, Jaap Oosterlaan, Yannis Paloyelis, Pedro M. Pan, Luca Passamonti, Wenceslao Peñate, K. Luan Phan, Kerstin J. Plessen, Jesus Pujol, Karl Lundin Remnélius, Francisco Rivero, Katya Rubia, Ramiro Salas, Giovanni A. Salum, Theodore D. Satterthwaite, Anne Schienle, Elisabeth Schrammen, Koen R.J. Schruers, Gunter Schumann, Arjun Sethi, Tim Silk, Norbert Skokauskas, Jordan W. Smoller, Jair C. Soares, Lin Sørensen, Christina Stadler, Michael C. Stevens, Benjamin Straube, Thomas Straube, Andreas Ströhle, Gustavo Sudre, Denis G. Sukhodolsky, Kate Sully, Xiaoqiang Sun, Chad M. Sylvester, Nicola Toschi, Steven J.A. van der Werff, Alasdair Vance, Robert Vermeiren, Albert Wabnegger, Xiaoping Wang, Julia Wendt, Sarah Whittle, Julian Wiemer, Anderson M. Winkler, Hans U. Wittchen, Mon-Ju Wu, Qiong Wu, Tony T. Yang, Yunbo Yang, Shuqiao Yao, Jibiao Zhang, Jiansong Zhou, Andre Zugman, Giovana B. Zunta-Soares, Peter M. Zwanzger, Sophia I. Thomopoulos, Neda Jahanshad, Paul M. Thompson, Kevin Hilbert, Arielle Baskin-Sommers, Charlotte A.M. Cecil, Moji Aghajani, Daniel S. Pine, Nic J.A. van der Wee, Dan J. Stein, Nynke A. Groenewold, Janna Marie Bas-Hoogendam, Laura K.M. Han, Elena Pozzi, Lianne Schmaal, Barbara Franke, Martine Hoogman, Esther Walton, Stephane A. De Brito, Graeme Fairchild

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DOI
10.1016/j.biopsych.2025.08.003
Published
2026-08
Container
Biological Psychiatry
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/j.biopsych.2025.08.003,
  title = {Shared and Distinct Alterations in Brain Structure of Youth With Internalizing or Externalizing Disorders: Findings From the ENIGMA Antisocial Behavior, ADHD, Major Depressive Disorder, and Anxiety Working Groups},
  author = {Sophie Townend and Marlene Staginnus and Yidian Gao and Nina Alexander and Volker Arolt and Tobias Banaschewski and Katja Beesdo-Baum and Mark A. Bellgrove and Vivek Benegal and Robert J. Blair and Laura Blanco-Hinojo and Ole Jonas Boeken and Joscha Böhnlein and Sven Bölte and Linda M. Bonnekoh and Daniel Brandeis and Rodrigo A. Bressan and Fabian Breuer and Willem B. Bruin and Jan K. Buitelaar and Katie L. Burkhouse and Monica E. Calkins and Marta Cano and Narcis Cardoner and Hui Chen and Xianliang Chen and David R. Coghill and Olivier F. Colins and Colm G. Connolly and Michael C. Craig and Kathryn R. Cullen and Udo Dannlowski and Christopher G. Davey and Andrea Dietrich and Daifeng Dong and Christine M. Freitag and Thomas Frodl and Liesbet Goossens and Dominik Grotegerd and Raquel E. Gur and Ruben C. Gur and Jan Haavik and Cindy C. Hagan and Tim Hahn and Alfons O. Hamm and Ben J. Harrison and Catharina A. Hartman and Martin J. Herrmann and Tiffany C. Ho and Pieter J. Hoekstra and Bharath Holla and Karim Ibrahim and Andrea Jackowski and Hamidreza Jamalabadi and Yali Jiang and Tilo Kircher and Kerstin Konrad and Anna Kraus and Jonna Kuntsi and Till Langhammer and Luisa Lazaro and Elisabeth J. Leehr and Ulrike Lueken and Ren Ma and Frank P. MacMaster and Gisele G. Manfro and Anne Martinelli and Hannah Meinert and Susanne Meinert and Jarosław M. Michałowski and Qingsen Ming and Robert Moeck and Markus Muehlhan and Lilianne R. Mujica-Parodi and Benson Mwangi and Janina Neufeld and Joel T. Nigg and Ruth L. O’Gorman Tuura and Hyuntaek Oh and Jaap Oosterlaan and Yannis Paloyelis and Pedro M. Pan and Luca Passamonti and Wenceslao Peñate and K. Luan Phan and Kerstin J. Plessen and Jesus Pujol and Karl Lundin Remnélius and Francisco Rivero and Katya Rubia and Ramiro Salas and Giovanni A. Salum and Theodore D. Satterthwaite and Anne Schienle and Elisabeth Schrammen and Koen R.J. Schruers and Gunter Schumann and Arjun Sethi and Tim Silk and Norbert Skokauskas and Jordan W. Smoller and Jair C. Soares and Lin Sørensen and Christina Stadler and Michael C. Stevens and Benjamin Straube and Thomas Straube and Andreas Ströhle and Gustavo Sudre and Denis G. Sukhodolsky and Kate Sully and Xiaoqiang Sun and Chad M. Sylvester and Nicola Toschi and Steven J.A. van der Werff and Alasdair Vance and Robert Vermeiren and Albert Wabnegger and Xiaoping Wang and Julia Wendt and Sarah Whittle and Julian Wiemer and Anderson M. Winkler and Hans U. Wittchen and Mon-Ju Wu and Qiong Wu and Tony T. Yang and Yunbo Yang and Shuqiao Yao and Jibiao Zhang and Jiansong Zhou and Andre Zugman and Giovana B. Zunta-Soares and Peter M. Zwanzger and Sophia I. Thomopoulos and Neda Jahanshad and Paul M. Thompson and Kevin Hilbert and Arielle Baskin-Sommers and Charlotte A.M. Cecil and Moji Aghajani and Daniel S. Pine and Nic J.A. van der Wee and Dan J. Stein and Nynke A. Groenewold and Janna Marie Bas-Hoogendam and Laura K.M. Han and Elena Pozzi and Lianne Schmaal and Barbara Franke and Martine Hoogman and Esther Walton and Stephane A. De Brito and Graeme Fairchild},
  year = {2026},
  journal = {Biological Psychiatry},
  doi = {10.1016/j.biopsych.2025.08.003},
  url = {https://doi.org/10.1016/j.biopsych.2025.08.003}
}

RIS

TY  - JOUR
TI  - Shared and Distinct Alterations in Brain Structure of Youth With Internalizing or Externalizing Disorders: Findings From the ENIGMA Antisocial Behavior, ADHD, Major Depressive Disorder, and Anxiety Working Groups
AU  - Sophie Townend
AU  - Marlene Staginnus
AU  - Yidian Gao
AU  - Nina Alexander
AU  - Volker Arolt
AU  - Tobias Banaschewski
AU  - Katja Beesdo-Baum
AU  - Mark A. Bellgrove
AU  - Vivek Benegal
AU  - Robert J. Blair
AU  - Laura Blanco-Hinojo
AU  - Ole Jonas Boeken
AU  - Joscha Böhnlein
AU  - Sven Bölte
AU  - Linda M. Bonnekoh
AU  - Daniel Brandeis
AU  - Rodrigo A. Bressan
AU  - Fabian Breuer
AU  - Willem B. Bruin
AU  - Jan K. Buitelaar
AU  - Katie L. Burkhouse
AU  - Monica E. Calkins
AU  - Marta Cano
AU  - Narcis Cardoner
AU  - Hui Chen
AU  - Xianliang Chen
AU  - David R. Coghill
AU  - Olivier F. Colins
AU  - Colm G. Connolly
AU  - Michael C. Craig
AU  - Kathryn R. Cullen
AU  - Udo Dannlowski
AU  - Christopher G. Davey
AU  - Andrea Dietrich
AU  - Daifeng Dong
AU  - Christine M. Freitag
AU  - Thomas Frodl
AU  - Liesbet Goossens
AU  - Dominik Grotegerd
AU  - Raquel E. Gur
AU  - Ruben C. Gur
AU  - Jan Haavik
AU  - Cindy C. Hagan
AU  - Tim Hahn
AU  - Alfons O. Hamm
AU  - Ben J. Harrison
AU  - Catharina A. Hartman
AU  - Martin J. Herrmann
AU  - Tiffany C. Ho
AU  - Pieter J. Hoekstra
AU  - Bharath Holla
AU  - Karim Ibrahim
AU  - Andrea Jackowski
AU  - Hamidreza Jamalabadi
AU  - Yali Jiang
AU  - Tilo Kircher
AU  - Kerstin Konrad
AU  - Anna Kraus
AU  - Jonna Kuntsi
AU  - Till Langhammer
AU  - Luisa Lazaro
AU  - Elisabeth J. Leehr
AU  - Ulrike Lueken
AU  - Ren Ma
AU  - Frank P. MacMaster
AU  - Gisele G. Manfro
AU  - Anne Martinelli
AU  - Hannah Meinert
AU  - Susanne Meinert
AU  - Jarosław M. Michałowski
AU  - Qingsen Ming
AU  - Robert Moeck
AU  - Markus Muehlhan
AU  - Lilianne R. Mujica-Parodi
AU  - Benson Mwangi
AU  - Janina Neufeld
AU  - Joel T. Nigg
AU  - Ruth L. O’Gorman Tuura
AU  - Hyuntaek Oh
AU  - Jaap Oosterlaan
AU  - Yannis Paloyelis
AU  - Pedro M. Pan
AU  - Luca Passamonti
AU  - Wenceslao Peñate
AU  - K. Luan Phan
AU  - Kerstin J. Plessen
AU  - Jesus Pujol
AU  - Karl Lundin Remnélius
AU  - Francisco Rivero
AU  - Katya Rubia
AU  - Ramiro Salas
AU  - Giovanni A. Salum
AU  - Theodore D. Satterthwaite
AU  - Anne Schienle
AU  - Elisabeth Schrammen
AU  - Koen R.J. Schruers
AU  - Gunter Schumann
AU  - Arjun Sethi
AU  - Tim Silk
AU  - Norbert Skokauskas
AU  - Jordan W. Smoller
AU  - Jair C. Soares
AU  - Lin Sørensen
AU  - Christina Stadler
AU  - Michael C. Stevens
AU  - Benjamin Straube
AU  - Thomas Straube
AU  - Andreas Ströhle
AU  - Gustavo Sudre
AU  - Denis G. Sukhodolsky
AU  - Kate Sully
AU  - Xiaoqiang Sun
AU  - Chad M. Sylvester
AU  - Nicola Toschi
AU  - Steven J.A. van der Werff
AU  - Alasdair Vance
AU  - Robert Vermeiren
AU  - Albert Wabnegger
AU  - Xiaoping Wang
AU  - Julia Wendt
AU  - Sarah Whittle
AU  - Julian Wiemer
AU  - Anderson M. Winkler
AU  - Hans U. Wittchen
AU  - Mon-Ju Wu
AU  - Qiong Wu
AU  - Tony T. Yang
AU  - Yunbo Yang
AU  - Shuqiao Yao
AU  - Jibiao Zhang
AU  - Jiansong Zhou
AU  - Andre Zugman
AU  - Giovana B. Zunta-Soares
AU  - Peter M. Zwanzger
AU  - Sophia I. Thomopoulos
AU  - Neda Jahanshad
AU  - Paul M. Thompson
AU  - Kevin Hilbert
AU  - Arielle Baskin-Sommers
AU  - Charlotte A.M. Cecil
AU  - Moji Aghajani
AU  - Daniel S. Pine
AU  - Nic J.A. van der Wee
AU  - Dan J. Stein
AU  - Nynke A. Groenewold
AU  - Janna Marie Bas-Hoogendam
AU  - Laura K.M. Han
AU  - Elena Pozzi
AU  - Lianne Schmaal
AU  - Barbara Franke
AU  - Martine Hoogman
AU  - Esther Walton
AU  - Stephane A. De Brito
AU  - Graeme Fairchild
PY  - 2026
JO  - Biological Psychiatry
DO  - 10.1016/j.biopsych.2025.08.003
UR  - https://doi.org/10.1016/j.biopsych.2025.08.003
ER  -

APA

Townend, S., Staginnus, M., Gao, Y., Alexander, N., Arolt, V., Banaschewski, T., Beesdo-Baum, K., Bellgrove, M. A., Benegal, V., Blair, R. J., Blanco-Hinojo, L., Boeken, O. J., Böhnlein, J., Bölte, S., Bonnekoh, L. M., Brandeis, D., Bressan, R. A., Breuer, F., Bruin, W. B., Buitelaar, J. K., Burkhouse, K. L., Calkins, M. E., Cano, M., Cardoner, N., Chen, H., Chen, X., Coghill, D. R., Colins, O. F., Connolly, C. G., Craig, M. C., Cullen, K. R., Dannlowski, U., Davey, C. G., Dietrich, A., Dong, D., Freitag, C. M., Frodl, T., Goossens, L., Grotegerd, D., Gur, R. E., Gur, R. C., Haavik, J., Hagan, C. C., Hahn, T., Hamm, A. O., Harrison, B. J., Hartman, C. A., Herrmann, M. J., Ho, T. C., Hoekstra, P. J., Holla, B., Ibrahim, K., Jackowski, A., Jamalabadi, H., Jiang, Y., Kircher, T., Konrad, K., Kraus, A., Kuntsi, J., Langhammer, T., Lazaro, L., Leehr, E. J., Lueken, U., Ma, R., MacMaster, F. P., Manfro, G. G., Martinelli, A., Meinert, H., Meinert, S., Michałowski, J. M., Ming, Q., Moeck, R., Muehlhan, M., Mujica-Parodi, L. R., Mwangi, B., Neufeld, J., Nigg, J. T., Tuura, R. L. O., Oh, H., Oosterlaan, J., Paloyelis, Y., Pan, P. M., Passamonti, L., Peñate, W., Phan, K. L., Plessen, K. J., Pujol, J., Remnélius, K. L., Rivero, F., Rubia, K., Salas, R., Salum, G. A., Satterthwaite, T. D., Schienle, A., Schrammen, E., Schruers, K. R., Schumann, G., Sethi, A., Silk, T., Skokauskas, N., Smoller, J. W., Soares, J. C., Sørensen, L., Stadler, C., Stevens, M. C., Straube, B., Straube, T., Ströhle, A., Sudre, G., Sukhodolsky, D. G., Sully, K., Sun, X., Sylvester, C. M., Toschi, N., Werff, S. J. V. D., Vance, A., Vermeiren, R., Wabnegger, A., Wang, X., Wendt, J., Whittle, S., Wiemer, J., Winkler, A. M., Wittchen, H. U., Wu, M., Wu, Q., Yang, T. T., Yang, Y., Yao, S., Zhang, J., Zhou, J., Zugman, A., Zunta-Soares, G. B., Zwanzger, P. M., Thomopoulos, S. I., Jahanshad, N., Thompson, P. M., Hilbert, K., Baskin-Sommers, A., Cecil, C. A., Aghajani, M., Pine, D. S., Wee, N. J. V. D., Stein, D. J., Groenewold, N. A., Bas-Hoogendam, J. M., Han, L. K., Pozzi, E., Schmaal, L., Franke, B., Hoogman, M., Walton, E., Brito, S. A. D., & Fairchild, G. (2026). Shared and Distinct Alterations in Brain Structure of Youth With Internalizing or Externalizing Disorders: Findings From the ENIGMA Antisocial Behavior, ADHD, Major Depressive Disorder, and Anxiety Working Groups. Biological Psychiatry. https://doi.org/10.1016/j.biopsych.2025.08.003

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