Blocking PD-L2 prevents senescent cell accumulation and age-related dysfunction

Selim Chaib, Larissa G.P. Langhi Prata, Masayoshi Suda, Andres Sola, Thomas J. Mitchell, Zacharias P. Anastasiadis, Hawley E. Kunz, Jia Nie, Stella G. Victorelli, Ricardo Lozano Flores, Moritz Weigl, Shimpei Kawamoto, Ken Uemura, Hyungsoo Kim, Binsheng Wang, Christina L. Inman, Tamar Pirtskhalava, Nino Giorgadze, Ailing Xue, Kurt O. Johnson, Jair M. Espindola-Netto, Sonja Suvakov, Jennet Hatamova, Erik S. Parker, Davyn Benitto Hartono, Vagisha Kulshreshtha, Jose Alberto Lopez-Dominguez, Aaron M. Deisinger, Allyson K. Palmer, Yi Zhu, Megan M. Weivoda, Anne Gingery, Robert Hromas, Vesna D. Garovic, João F. Passos, David B. Allison, Eiji Hara, Michael D. Jensen, Nicolas Musi, Stefan G. Tullius, Ze’ev A. Ronai, Manuel Serrano, Ming Xu, Ian R. Lanza, Yuji Ikeno, Tamara Tchkonia, James L. Kirkland

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DOI: 10.1016/j.cmet.2026.08.014
Published: 2026-09
Container: Cell Metabolism
Publisher: Elsevier BV
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1016/j.cmet.2026.08.014,
  title = {Blocking PD-L2 prevents senescent cell accumulation and age-related dysfunction},
  author = {Selim Chaib and Larissa G.P. Langhi Prata and Masayoshi Suda and Andres Sola and Thomas J. Mitchell and Zacharias P. Anastasiadis and Hawley E. Kunz and Jia Nie and Stella G. Victorelli and Ricardo Lozano Flores and Moritz Weigl and Shimpei Kawamoto and Ken Uemura and Hyungsoo Kim and Binsheng Wang and Christina L. Inman and Tamar Pirtskhalava and Nino Giorgadze and Ailing Xue and Kurt O. Johnson and Jair M. Espindola-Netto and Sonja Suvakov and Jennet Hatamova and Erik S. Parker and Davyn Benitto Hartono and Vagisha Kulshreshtha and Jose Alberto Lopez-Dominguez and Aaron M. Deisinger and Allyson K. Palmer and Yi Zhu and Megan M. Weivoda and Anne Gingery and Robert Hromas and Vesna D. Garovic and João F. Passos and David B. Allison and Eiji Hara and Michael D. Jensen and Nicolas Musi and Stefan G. Tullius and Ze’ev A. Ronai and Manuel Serrano and Ming Xu and Ian R. Lanza and Yuji Ikeno and Tamara Tchkonia and James L. Kirkland},
  year = {2026},
  journal = {Cell Metabolism},
  doi = {10.1016/j.cmet.2026.08.014},
  url = {https://doi.org/10.1016/j.cmet.2026.08.014}
}

RIS

TY  - JOUR
TI  - Blocking PD-L2 prevents senescent cell accumulation and age-related dysfunction
AU  - Selim Chaib
AU  - Larissa G.P. Langhi Prata
AU  - Masayoshi Suda
AU  - Andres Sola
AU  - Thomas J. Mitchell
AU  - Zacharias P. Anastasiadis
AU  - Hawley E. Kunz
AU  - Jia Nie
AU  - Stella G. Victorelli
AU  - Ricardo Lozano Flores
AU  - Moritz Weigl
AU  - Shimpei Kawamoto
AU  - Ken Uemura
AU  - Hyungsoo Kim
AU  - Binsheng Wang
AU  - Christina L. Inman
AU  - Tamar Pirtskhalava
AU  - Nino Giorgadze
AU  - Ailing Xue
AU  - Kurt O. Johnson
AU  - Jair M. Espindola-Netto
AU  - Sonja Suvakov
AU  - Jennet Hatamova
AU  - Erik S. Parker
AU  - Davyn Benitto Hartono
AU  - Vagisha Kulshreshtha
AU  - Jose Alberto Lopez-Dominguez
AU  - Aaron M. Deisinger
AU  - Allyson K. Palmer
AU  - Yi Zhu
AU  - Megan M. Weivoda
AU  - Anne Gingery
AU  - Robert Hromas
AU  - Vesna D. Garovic
AU  - João F. Passos
AU  - David B. Allison
AU  - Eiji Hara
AU  - Michael D. Jensen
AU  - Nicolas Musi
AU  - Stefan G. Tullius
AU  - Ze’ev A. Ronai
AU  - Manuel Serrano
AU  - Ming Xu
AU  - Ian R. Lanza
AU  - Yuji Ikeno
AU  - Tamara Tchkonia
AU  - James L. Kirkland
PY  - 2026
JO  - Cell Metabolism
DO  - 10.1016/j.cmet.2026.08.014
UR  - https://doi.org/10.1016/j.cmet.2026.08.014
ER  -

APA

Chaib, S., Prata, L. G. L., Suda, M., Sola, A., Mitchell, T. J., Anastasiadis, Z. P., Kunz, H. E., Nie, J., Victorelli, S. G., Flores, R. L., Weigl, M., Kawamoto, S., Uemura, K., Kim, H., Wang, B., Inman, C. L., Pirtskhalava, T., Giorgadze, N., Xue, A., Johnson, K. O., Espindola-Netto, J. M., Suvakov, S., Hatamova, J., Parker, E. S., Hartono, D. B., Kulshreshtha, V., Lopez-Dominguez, J. A., Deisinger, A. M., Palmer, A. K., Zhu, Y., Weivoda, M. M., Gingery, A., Hromas, R., Garovic, V. D., Passos, J. F., Allison, D. B., Hara, E., Jensen, M. D., Musi, N., Tullius, S. G., Ronai, Z. A., Serrano, M., Xu, M., Lanza, I. R., Ikeno, Y., Tchkonia, T., & Kirkland, J. L. (2026). Blocking PD-L2 prevents senescent cell accumulation and age-related dysfunction. Cell Metabolism. https://doi.org/10.1016/j.cmet.2026.08.014

Source records

crossref · retrieved 2026-09-25T16:42:55.806Z