Neoadjuvant pembrolizumab with a watch‑and‑wait strategy for localized MSI/dMMR colon cancer: Study protocol for a randomized GERCOR 109 – PRODIGE 84 phase II trial (PREMICES)

Jérémie H. Lefevre, Olivier Dubreuil, Raphael Colle, David Tougeron, Angélique Vienot, Aurélien Dupré, Clémence Toullec, Denis Smith, Rosine Guimbaud, Benoist Chibaudel, Marie-Line Garcia Larnicol, Dewi Vernerey, Romain Cohen

Open source

DOI
10.1016/j.dld.2025.11.003
Published
2026-01
Container
Digestive and Liver Disease
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/j.dld.2025.11.003,
  title = {Neoadjuvant pembrolizumab with a watch‑and‑wait strategy for localized MSI/dMMR colon cancer: Study protocol for a randomized GERCOR 109 – PRODIGE 84 phase II trial (PREMICES)},
  author = {Jérémie H. Lefevre and Olivier Dubreuil and Raphael Colle and David Tougeron and Angélique Vienot and Aurélien Dupré and Clémence Toullec and Denis Smith and Rosine Guimbaud and Benoist Chibaudel and Marie-Line Garcia Larnicol and Dewi Vernerey and Romain Cohen},
  year = {2026},
  journal = {Digestive and Liver Disease},
  doi = {10.1016/j.dld.2025.11.003},
  url = {https://doi.org/10.1016/j.dld.2025.11.003}
}

RIS

TY  - JOUR
TI  - Neoadjuvant pembrolizumab with a watch‑and‑wait strategy for localized MSI/dMMR colon cancer: Study protocol for a randomized GERCOR 109 – PRODIGE 84 phase II trial (PREMICES)
AU  - Jérémie H. Lefevre
AU  - Olivier Dubreuil
AU  - Raphael Colle
AU  - David Tougeron
AU  - Angélique Vienot
AU  - Aurélien Dupré
AU  - Clémence Toullec
AU  - Denis Smith
AU  - Rosine Guimbaud
AU  - Benoist Chibaudel
AU  - Marie-Line Garcia Larnicol
AU  - Dewi Vernerey
AU  - Romain Cohen
PY  - 2026
JO  - Digestive and Liver Disease
DO  - 10.1016/j.dld.2025.11.003
UR  - https://doi.org/10.1016/j.dld.2025.11.003
ER  - 

APA

Lefevre, J. H., Dubreuil, O., Colle, R., Tougeron, D., Vienot, A., Dupré, A., Toullec, C., Smith, D., Guimbaud, R., Chibaudel, B., Larnicol, M. G., Vernerey, D., & Cohen, R. (2026). Neoadjuvant pembrolizumab with a watch‑and‑wait strategy for localized MSI/dMMR colon cancer: Study protocol for a randomized GERCOR 109 – PRODIGE 84 phase II trial (PREMICES). Digestive and Liver Disease. https://doi.org/10.1016/j.dld.2025.11.003

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