Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults.

Abouyannis M, Nyambura YK, Ngome S, Riako D, Musyoki J, Muiruri C, Orindi B, Else L, Amara A, Dickinson L, Clare RH, Albulescu LO, Westhorpe AP, Kool J, Adetifa I, Ndungu FM, FitzGerald R, Khoo S, Lalloo DG, Casewell NR, Hamaluba M

Open source

DOI
10.1016/j.ebiom.2025.105600
Published
2025 Mar
Container
EBioMedicine
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.1016/j.ebiom.2025.105600,
  title = {Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults.},
  author = {Abouyannis M and Nyambura YK and Ngome S and Riako D and Musyoki J and Muiruri C and Orindi B and Else L and Amara A and Dickinson L and Clare RH and Albulescu LO and Westhorpe AP and Kool J and Adetifa I and Ndungu FM and FitzGerald R and Khoo S and Lalloo DG and Casewell NR and Hamaluba M},
  year = {2025},
  journal = {EBioMedicine},
  doi = {10.1016/j.ebiom.2025.105600},
  url = {https://doi.org/10.1016/j.ebiom.2025.105600}
}

RIS

TY  - JOUR
TI  - Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults.
AU  - Abouyannis M
AU  - Nyambura YK
AU  - Ngome S
AU  - Riako D
AU  - Musyoki J
AU  - Muiruri C
AU  - Orindi B
AU  - Else L
AU  - Amara A
AU  - Dickinson L
AU  - Clare RH
AU  - Albulescu LO
AU  - Westhorpe AP
AU  - Kool J
AU  - Adetifa I
AU  - Ndungu FM
AU  - FitzGerald R
AU  - Khoo S
AU  - Lalloo DG
AU  - Casewell NR
AU  - Hamaluba M
PY  - 2025
JO  - EBioMedicine
DO  - 10.1016/j.ebiom.2025.105600
UR  - https://doi.org/10.1016/j.ebiom.2025.105600
ER  - 

APA

M, A., YK, N., S, N., D, R., J, M., C, M., B, O., L, E., A, A., L, D., RH, C., LO, A., AP, W., J, K., I, A., FM, N., R, F., S, K., DG, L., NR, C., & M, H. (2025). Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults.. EBioMedicine. https://doi.org/10.1016/j.ebiom.2025.105600

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