Fixed dosing versus weight-based dosing of HIV-1 prophylactic monoclonal antibodies in adults: a post-hoc, cross-protocol pharmacokinetics modelling study.

Huang Y, Zhang L, Gelderblom H, Seaton KE, Yates NL, Paez CA, Karuna ST, Andrew P, Gamble T, Robinson ST, Ledgerwood JE, Hyrien O, Walsh SR, Gay CL, Gwira JA, Spiegel HML, Sobieszczyk ME, Mannheimer SB, Edupuganti S, Hurt CB, Stephenson KE, Yu C, Kelley CF, Mahomed S, Siegel M, Yacovone M, Pensiero MN, Donnell D, Cohen MS, Corey L, Gilbert PB, Koup RA, Tomaras GD, VRC 605, HVTN 127/HPTN 087, HVTN 130/HPTN 089, HVTN 136/HPTN 092, and HVTN 140/HPTN 101 study teams.

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DOI: 10.1016/j.ebiom.2025.105804
Published: 2025-06-13
Container: EBioMedicine
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1016/j.ebiom.2025.105804,
  title = {Fixed dosing versus weight-based dosing of HIV-1 prophylactic monoclonal antibodies in adults: a post-hoc, cross-protocol pharmacokinetics modelling study.},
  author = {Huang Y and  Zhang L and  Gelderblom H and  Seaton KE and  Yates NL and  Paez CA and  Karuna ST and  Andrew P and  Gamble T and  Robinson ST and  Ledgerwood JE and  Hyrien O and  Walsh SR and  Gay CL and  Gwira JA and  Spiegel HML and  Sobieszczyk ME and  Mannheimer SB and  Edupuganti S and  Hurt CB and  Stephenson KE and  Yu C and  Kelley CF and  Mahomed S and  Siegel M and  Yacovone M and  Pensiero MN and  Donnell D and  Cohen MS and  Corey L and  Gilbert PB and  Koup RA and  Tomaras GD and  VRC 605 and  HVTN 127/HPTN 087 and  HVTN 130/HPTN 089 and  HVTN 136/HPTN 092 and  and HVTN 140/HPTN 101 study teams.},
  year = {2025},
  journal = {EBioMedicine},
  doi = {10.1016/j.ebiom.2025.105804},
  url = {https://doi.org/10.1016/j.ebiom.2025.105804}
}

RIS

TY  - JOUR
TI  - Fixed dosing versus weight-based dosing of HIV-1 prophylactic monoclonal antibodies in adults: a post-hoc, cross-protocol pharmacokinetics modelling study.
AU  - Huang Y
AU  -  Zhang L
AU  -  Gelderblom H
AU  -  Seaton KE
AU  -  Yates NL
AU  -  Paez CA
AU  -  Karuna ST
AU  -  Andrew P
AU  -  Gamble T
AU  -  Robinson ST
AU  -  Ledgerwood JE
AU  -  Hyrien O
AU  -  Walsh SR
AU  -  Gay CL
AU  -  Gwira JA
AU  -  Spiegel HML
AU  -  Sobieszczyk ME
AU  -  Mannheimer SB
AU  -  Edupuganti S
AU  -  Hurt CB
AU  -  Stephenson KE
AU  -  Yu C
AU  -  Kelley CF
AU  -  Mahomed S
AU  -  Siegel M
AU  -  Yacovone M
AU  -  Pensiero MN
AU  -  Donnell D
AU  -  Cohen MS
AU  -  Corey L
AU  -  Gilbert PB
AU  -  Koup RA
AU  -  Tomaras GD
AU  -  VRC 605
AU  -  HVTN 127/HPTN 087
AU  -  HVTN 130/HPTN 089
AU  -  HVTN 136/HPTN 092
AU  -  and HVTN 140/HPTN 101 study teams.
PY  - 2025
JO  - EBioMedicine
DO  - 10.1016/j.ebiom.2025.105804
UR  - https://doi.org/10.1016/j.ebiom.2025.105804
ER  -

APA

Y, H., L, Z., H, G., KE, S., NL, Y., CA, P., ST, K., P, A., T, G., ST, R., JE, L., O, H., SR, W., CL, G., JA, G., HML, S., ME, S., SB, M., S, E., CB, H., KE, S., C, Y., CF, K., S, M., M, S., M, Y., MN, P., D, D., MS, C., L, C., PB, G., RA, K., GD, T., 605, V., 087, H. 1., 089, H. 1., 092, H. 1., & teams., A. H. 1. 1. S. (2025). Fixed dosing versus weight-based dosing of HIV-1 prophylactic monoclonal antibodies in adults: a post-hoc, cross-protocol pharmacokinetics modelling study.. EBioMedicine. https://doi.org/10.1016/j.ebiom.2025.105804

Source records

europe-pmc · retrieved 2026-09-26T19:41:46.700Z