Effectiveness and safety of selective internal radiation therapy using yttrium-90 glass microspheres for hepatocellular carcinoma: real-world results from the multi-center prospective PROACTIF cohort of 989 patients

Boris Guiu, Clément Bailly, Eric Vibert, Ghoufrane Tlili, Denis Mariano-Goulart, Julien Edeline, Yann Touchefeu, Emmanuel Durand, Jean Frédéric Blanc, Julia Chalaye, Hélène Regnault, Antoine Bouvier, Geraldine Sergent, Christian Sengel, Stéphane Renaud, Agnès Rode, Claude Somma, Patrick Chevallier, Vincent Habouzit, Isabelle Brenot-Rossi, Anthony Dohan, Lambros Tselikas, Thierry DeBaère, Sylvain Manfredi, Arnaud Dieudonné, Kirk Fowers, Eveline Boucher, Binal Patel, Eric Vicaut, Etienne Garin, Emmanuel Durand, Olivier Meyrignac, Clara Prud'homme, Gilles Grimon, Anthony Dohan, Maxime Barat, Raphael Dautry, Julia Chalaye, Hélène Regnault, Hicham Kobeiter, Haytham Derbel, Eric Vicaut, Eric Vibert, Olivier Rosmorduc, Anton Pachev, Thomas Aparicio, Laetitia Vercellino, Etienne Garin, Julien Edeline, Yann Rolland, Julien Farce, Samuel Lesourd, Xavier Palard-Novello, Inna Dygai-Cochet, François Godard, Romain Popoff, Julie Pellegrinelli, Arnaud Dieudonné, Stéphanie Becker, Stéphane Renaud, Aymeric Guibal, Mohamed Abdel-Rehim, Faiza Khemissa Akouz, Sibel Isal, Charles Mastier, Arnaud Muller, Guillaume Guthier, Paul Calame, Hatem Boulahdour, Vincent Di Martino, Elodie Chevalier, Valérie Laurent, Xavier Orry, Thierry Yzet, Eric Nguyen-Khac, Vandici Ovidiu-Florian, Chalabia Fergani, Antoine Bouvier, Pacome Fosse, Frederic Oberti, Ghoufrane Tlili, Jean Frédéric Blanc, Panteleimon Papadopoulos, Ronan Abral, Antoine Boizet, Jean Romain Risson, Sylvain Manfredi, Francois Ghiringhelli, Romaric Loffroy, Michel Greget, Fabrice Hubele, Claude Somma, Olivier Durieux, Géraldine Sergent, Clio Baillet, Massih Ningarhari, Christian Sengel, Julie Roux, Julien Ghelfi, Thomas Decaens, Clément Bailly, Yann Touchefeu, Frederic Douane, Matthieu Barbaud, Patrick Chevallier, Mohamed El Zibawi, Philippe Viaud, Micheline Razzouk, Jean Goupil, Melanie Sainmont, Jean-Marie Peron, Philippe Otal, Fatima-Zohra Mokrane, David Sefrioui, Frederic Di Fiore, Vincent Habouzit, Remi Grange, Jean Marc Phelip, Jean-Pierre Tasu, David Tougeron, Rémy Perdrisot, Isabelle Brenot-Rossi, Gilles Piana, Brice Chanez, Daniel Ouk, Clément Mennetrey, Franck Grillet, Amine Bouhamama, Sandrine Parisse-Di Martino, Marco Dioguardi Burgio, Maxime Ronot, Rachida Lebtahi, Mohammed Bouattour, Laurent Milot, Jérôme Dumortier, Boris Guiu, Denis Mariano-Goulart, Eric Assenat, Carole Allimant, Christine Latry Kuhn, Marjolaine Fourcade, Agnès Rode, Philippe Merle, Jean Palussière, Vincent Prega-Renaud, Thierry De Baère, Lambros Tselikas, Iulian Enescu

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DOI: 10.1016/j.eclinm.2026.103884
Published: 2026-05
Container: eClinicalMedicine
Publisher: Elsevier BV
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BibTeX

@article{allodium:10.1016/j.eclinm.2026.103884,
  title = {Effectiveness and safety of selective internal radiation therapy using yttrium-90 glass microspheres for hepatocellular carcinoma: real-world results from the multi-center prospective PROACTIF cohort of 989 patients},
  author = {Boris Guiu and Clément Bailly and Eric Vibert and Ghoufrane Tlili and Denis Mariano-Goulart and Julien Edeline and Yann Touchefeu and Emmanuel Durand and Jean Frédéric Blanc and Julia Chalaye and Hélène Regnault and Antoine Bouvier and Geraldine Sergent and Christian Sengel and Stéphane Renaud and Agnès Rode and Claude Somma and Patrick Chevallier and Vincent Habouzit and Isabelle Brenot-Rossi and Anthony Dohan and Lambros Tselikas and Thierry DeBaère and Sylvain Manfredi and Arnaud Dieudonné and Kirk Fowers and Eveline Boucher and Binal Patel and Eric Vicaut and Etienne Garin and Emmanuel Durand and Olivier Meyrignac and Clara Prud'homme and Gilles Grimon and Anthony Dohan and Maxime Barat and Raphael Dautry and Julia Chalaye and Hélène Regnault and Hicham Kobeiter and Haytham Derbel and Eric Vicaut and Eric Vibert and Olivier Rosmorduc and Anton Pachev and Thomas Aparicio and Laetitia Vercellino and Etienne Garin and Julien Edeline and Yann Rolland and Julien Farce and Samuel Lesourd and Xavier Palard-Novello and Inna Dygai-Cochet and François Godard and Romain Popoff and Julie Pellegrinelli and Arnaud Dieudonné and Stéphanie Becker and Stéphane Renaud and Aymeric Guibal and Mohamed Abdel-Rehim and Faiza Khemissa Akouz and Sibel Isal and Charles Mastier and Arnaud Muller and Guillaume Guthier and Paul Calame and Hatem Boulahdour and Vincent Di Martino and Elodie Chevalier and Valérie Laurent and Xavier Orry and Thierry Yzet and Eric Nguyen-Khac and Vandici Ovidiu-Florian and Chalabia Fergani and Antoine Bouvier and Pacome Fosse and Frederic Oberti and Ghoufrane Tlili and Jean Frédéric Blanc and Panteleimon Papadopoulos and Ronan Abral and Antoine Boizet and Jean Romain Risson and Sylvain Manfredi and Francois Ghiringhelli and Romaric Loffroy and Michel Greget and Fabrice Hubele and Claude Somma and Olivier Durieux and Géraldine Sergent and Clio Baillet and Massih Ningarhari and Christian Sengel and Julie Roux and Julien Ghelfi and Thomas Decaens and Clément Bailly and Yann Touchefeu and Frederic Douane and Matthieu Barbaud and Patrick Chevallier and Mohamed El Zibawi and Philippe Viaud and Micheline Razzouk and Jean Goupil and Melanie Sainmont and Jean-Marie Peron and Philippe Otal and Fatima-Zohra Mokrane and David Sefrioui and Frederic Di Fiore and Vincent Habouzit and Remi Grange and Jean Marc Phelip and Jean-Pierre Tasu and David Tougeron and Rémy Perdrisot and Isabelle Brenot-Rossi and Gilles Piana and Brice Chanez and Daniel Ouk and Clément Mennetrey and Franck Grillet and Amine Bouhamama and Sandrine Parisse-Di Martino and Marco Dioguardi Burgio and Maxime Ronot and Rachida Lebtahi and Mohammed Bouattour and Laurent Milot and Jérôme Dumortier and Boris Guiu and Denis Mariano-Goulart and Eric Assenat and Carole Allimant and Christine Latry Kuhn and Marjolaine Fourcade and Agnès Rode and Philippe Merle and Jean Palussière and Vincent Prega-Renaud and Thierry De Baère and Lambros Tselikas and Iulian Enescu},
  year = {2026},
  journal = {eClinicalMedicine},
  doi = {10.1016/j.eclinm.2026.103884},
  url = {https://doi.org/10.1016/j.eclinm.2026.103884}
}

RIS

TY  - JOUR
TI  - Effectiveness and safety of selective internal radiation therapy using yttrium-90 glass microspheres for hepatocellular carcinoma: real-world results from the multi-center prospective PROACTIF cohort of 989 patients
AU  - Boris Guiu
AU  - Clément Bailly
AU  - Eric Vibert
AU  - Ghoufrane Tlili
AU  - Denis Mariano-Goulart
AU  - Julien Edeline
AU  - Yann Touchefeu
AU  - Emmanuel Durand
AU  - Jean Frédéric Blanc
AU  - Julia Chalaye
AU  - Hélène Regnault
AU  - Antoine Bouvier
AU  - Geraldine Sergent
AU  - Christian Sengel
AU  - Stéphane Renaud
AU  - Agnès Rode
AU  - Claude Somma
AU  - Patrick Chevallier
AU  - Vincent Habouzit
AU  - Isabelle Brenot-Rossi
AU  - Anthony Dohan
AU  - Lambros Tselikas
AU  - Thierry DeBaère
AU  - Sylvain Manfredi
AU  - Arnaud Dieudonné
AU  - Kirk Fowers
AU  - Eveline Boucher
AU  - Binal Patel
AU  - Eric Vicaut
AU  - Etienne Garin
AU  - Emmanuel Durand
AU  - Olivier Meyrignac
AU  - Clara Prud'homme
AU  - Gilles Grimon
AU  - Anthony Dohan
AU  - Maxime Barat
AU  - Raphael Dautry
AU  - Julia Chalaye
AU  - Hélène Regnault
AU  - Hicham Kobeiter
AU  - Haytham Derbel
AU  - Eric Vicaut
AU  - Eric Vibert
AU  - Olivier Rosmorduc
AU  - Anton Pachev
AU  - Thomas Aparicio
AU  - Laetitia Vercellino
AU  - Etienne Garin
AU  - Julien Edeline
AU  - Yann Rolland
AU  - Julien Farce
AU  - Samuel Lesourd
AU  - Xavier Palard-Novello
AU  - Inna Dygai-Cochet
AU  - François Godard
AU  - Romain Popoff
AU  - Julie Pellegrinelli
AU  - Arnaud Dieudonné
AU  - Stéphanie Becker
AU  - Stéphane Renaud
AU  - Aymeric Guibal
AU  - Mohamed Abdel-Rehim
AU  - Faiza Khemissa Akouz
AU  - Sibel Isal
AU  - Charles Mastier
AU  - Arnaud Muller
AU  - Guillaume Guthier
AU  - Paul Calame
AU  - Hatem Boulahdour
AU  - Vincent Di Martino
AU  - Elodie Chevalier
AU  - Valérie Laurent
AU  - Xavier Orry
AU  - Thierry Yzet
AU  - Eric Nguyen-Khac
AU  - Vandici Ovidiu-Florian
AU  - Chalabia Fergani
AU  - Antoine Bouvier
AU  - Pacome Fosse
AU  - Frederic Oberti
AU  - Ghoufrane Tlili
AU  - Jean Frédéric Blanc
AU  - Panteleimon Papadopoulos
AU  - Ronan Abral
AU  - Antoine Boizet
AU  - Jean Romain Risson
AU  - Sylvain Manfredi
AU  - Francois Ghiringhelli
AU  - Romaric Loffroy
AU  - Michel Greget
AU  - Fabrice Hubele
AU  - Claude Somma
AU  - Olivier Durieux
AU  - Géraldine Sergent
AU  - Clio Baillet
AU  - Massih Ningarhari
AU  - Christian Sengel
AU  - Julie Roux
AU  - Julien Ghelfi
AU  - Thomas Decaens
AU  - Clément Bailly
AU  - Yann Touchefeu
AU  - Frederic Douane
AU  - Matthieu Barbaud
AU  - Patrick Chevallier
AU  - Mohamed El Zibawi
AU  - Philippe Viaud
AU  - Micheline Razzouk
AU  - Jean Goupil
AU  - Melanie Sainmont
AU  - Jean-Marie Peron
AU  - Philippe Otal
AU  - Fatima-Zohra Mokrane
AU  - David Sefrioui
AU  - Frederic Di Fiore
AU  - Vincent Habouzit
AU  - Remi Grange
AU  - Jean Marc Phelip
AU  - Jean-Pierre Tasu
AU  - David Tougeron
AU  - Rémy Perdrisot
AU  - Isabelle Brenot-Rossi
AU  - Gilles Piana
AU  - Brice Chanez
AU  - Daniel Ouk
AU  - Clément Mennetrey
AU  - Franck Grillet
AU  - Amine Bouhamama
AU  - Sandrine Parisse-Di Martino
AU  - Marco Dioguardi Burgio
AU  - Maxime Ronot
AU  - Rachida Lebtahi
AU  - Mohammed Bouattour
AU  - Laurent Milot
AU  - Jérôme Dumortier
AU  - Boris Guiu
AU  - Denis Mariano-Goulart
AU  - Eric Assenat
AU  - Carole Allimant
AU  - Christine Latry Kuhn
AU  - Marjolaine Fourcade
AU  - Agnès Rode
AU  - Philippe Merle
AU  - Jean Palussière
AU  - Vincent Prega-Renaud
AU  - Thierry De Baère
AU  - Lambros Tselikas
AU  - Iulian Enescu
PY  - 2026
JO  - eClinicalMedicine
DO  - 10.1016/j.eclinm.2026.103884
UR  - https://doi.org/10.1016/j.eclinm.2026.103884
ER  -

APA

Guiu, B., Bailly, C., Vibert, E., Tlili, G., Mariano-Goulart, D., Edeline, J., Touchefeu, Y., Durand, E., Blanc, J. F., Chalaye, J., Regnault, H., Bouvier, A., Sergent, G., Sengel, C., Renaud, S., Rode, A., Somma, C., Chevallier, P., Habouzit, V., Brenot-Rossi, I., Dohan, A., Tselikas, L., DeBaère, T., Manfredi, S., Dieudonné, A., Fowers, K., Boucher, E., Patel, B., Vicaut, E., Garin, E., Durand, E., Meyrignac, O., Prud'homme, C., Grimon, G., Dohan, A., Barat, M., Dautry, R., Chalaye, J., Regnault, H., Kobeiter, H., Derbel, H., Vicaut, E., Vibert, E., Rosmorduc, O., Pachev, A., Aparicio, T., Vercellino, L., Garin, E., Edeline, J., Rolland, Y., Farce, J., Lesourd, S., Palard-Novello, X., Dygai-Cochet, I., Godard, F., Popoff, R., Pellegrinelli, J., Dieudonné, A., Becker, S., Renaud, S., Guibal, A., Abdel-Rehim, M., Akouz, F. K., Isal, S., Mastier, C., Muller, A., Guthier, G., Calame, P., Boulahdour, H., Martino, V. D., Chevalier, E., Laurent, V., Orry, X., Yzet, T., Nguyen-Khac, E., Ovidiu-Florian, V., Fergani, C., Bouvier, A., Fosse, P., Oberti, F., Tlili, G., Blanc, J. F., Papadopoulos, P., Abral, R., Boizet, A., Risson, J. R., Manfredi, S., Ghiringhelli, F., Loffroy, R., Greget, M., Hubele, F., Somma, C., Durieux, O., Sergent, G., Baillet, C., Ningarhari, M., Sengel, C., Roux, J., Ghelfi, J., Decaens, T., Bailly, C., Touchefeu, Y., Douane, F., Barbaud, M., Chevallier, P., Zibawi, M. E., Viaud, P., Razzouk, M., Goupil, J., Sainmont, M., Peron, J., Otal, P., Mokrane, F., Sefrioui, D., Fiore, F. D., Habouzit, V., Grange, R., Phelip, J. M., Tasu, J., Tougeron, D., Perdrisot, R., Brenot-Rossi, I., Piana, G., Chanez, B., Ouk, D., Mennetrey, C., Grillet, F., Bouhamama, A., Martino, S. P., Burgio, M. D., Ronot, M., Lebtahi, R., Bouattour, M., Milot, L., Dumortier, J., Guiu, B., Mariano-Goulart, D., Assenat, E., Allimant, C., Kuhn, C. L., Fourcade, M., Rode, A., Merle, P., Palussière, J., Prega-Renaud, V., Baère, T. D., Tselikas, L., & Enescu, I. (2026). Effectiveness and safety of selective internal radiation therapy using yttrium-90 glass microspheres for hepatocellular carcinoma: real-world results from the multi-center prospective PROACTIF cohort of 989 patients. eClinicalMedicine. https://doi.org/10.1016/j.eclinm.2026.103884

Source records

crossref · retrieved 2026-09-25T11:33:37.821Z