Safety of routine antimicrobial prophylaxis for surgery (SAPPHIRE): a prospective multi-centre cohort study
- DOI
- 10.1016/j.eclinm.2026.104151
- Published
- 2026-09
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- eClinicalMedicine
- Publisher
- Elsevier BV
- Open access
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@article{allodium:10.1016/j.eclinm.2026.104151,
title = {Safety of routine antimicrobial prophylaxis for surgery (SAPPHIRE): a prospective multi-centre cohort study},
author = {Tom E.F. Abbott and Priyanthi Dias and Jai Vairale and Salma Begum and Kamran Khan and Alexander J. Fowler and Vikas Kaura and Rupert M. Pearse and Tom E.F. Abbott and Priyanthi Dias and Salma Begum and Jai Vairale and Russ Hewson and Alex Fowler and Kamran Khan and Vikas Kaura and Rupert M. Pearse and Louise Savic and Louise Savic and Tom E.F. Abbott and Salma Begum and Priyanthi Dias and Kamran Khan and Vikas Kaura and Russell Hewson and Jai Vairale and Rupert M. Pearse and Tom E.F. Abbott and Louise Savic and Salma Begum and Priyanthi Dias and Alex Fowler and Vikas Kaura and Rupert M. Pearse and Robert Lewis and Tracy Griffiths and Aashima Bakshi and Katrina Cooke and Chiara De Leonardis and Edyta Klata and Emma Williams and Kerry Smith and Michelle Dotchin and Robert Lewis and Vanessa Rivers and Caitlin Palmer and Natalie Keenan and Christine Hibbert and Helen Wassall and Jan Tomkinson and Joanne Bradley-Potts and Katherine Rose and Philippa Hill and Sarah Ward and Hannah Brennan and Mohamed Mahmoud and Brendan Sloan and Mark Southworth and Anna Littlejohns and Daniel Thomas and Diana Kluczna and Nicholas Wroe and Tracy Langcake and James Roden and Chun Chiu and Jordon Almas and Matthew Howe and Rachel Murali-Krishnan and Sarah Buckley and Elizabeth Denis and Thelma Darian and Alexandra Metcalfe and Amy Major and Abigail Crew and Ronelle Mouton and Amy Dodd and Alexander Ferriman and Carmel Oliver and Edward Mew and Kate Skidmore and Kat Herneman and Richard Elston and Stella Arthur Quarm and Timothy Walker and Gayani Jayasooriya and William Turner and Sejung Park and Isabel Bradley and Ramy Mahmoud and Sunitha Eswarappa and Roshni Molls and Amanda Davis and Judith Bradley and Margaret Grout and Jackie Latimer and Muqsith Rasool and Aparna George and George Joseph and Soumyajit Saha and Tatiana Pogreban and Toko Akangadjo and Mohammed Sabihul Islam and Sanjay K. Sakholiya and Amila Herath and Marvin Mutebi and Christopher Marsh and Alison Kirby and Andrew Ike and Annette Moreton and Catherine Bressington and Jenny Pullen and Jessica Sellick and Lowri Jones and Nora Seager-Wilkendorf and Ros Knight and Rose Warren and Sara Burnard and Spandana Gumpula and Wendy Duberry and Shaman Jhanji and Holly Townsend-Renn and Anna Warrington and David Parkinson and Ethel Black and Holly Hogan and Imran Ali and Maxime Caron-Goudreau and Kayleigh Jessop and Samantha Black and Dilukshi Wickramasinghe and Linda Ofori and Lisa Parker and Patience Nkala and Thomas Gower and Tom Hatton and Trudi Chronnell and Sam Martin and George Clews and Victoria Ewasiuk and Anais Mutarambirwa and Clarissa Madla and Anil P. Hormis and Rachel Walker and Caroline Bird and Cheryl Graham and Laura Naish and Samuel Yale and Alasdair Sandland and Joyce Yeung and Helen Taylor and Jo Gresty and Juliet Sebastian and Mehwaish Zulfiqar and Meirvaan Basra and Fred Parker and Teresa Melody and Eleanor Reeves and Celina Maliaykal and Sundar Ashok and Cassandra George and Christopher Black and Islam Abousharkh and Layla Guscoth and Louise Phaure and Sophie Boles and Sreedevi Rajalingam and Rhona Sinclair and Iain J. McCullagh and Rikzing D. Bhutia and Sabrina Kapur and Wendell Storr and Adam Cookson and Adam Mowatt and Alex Wilson and Arti Gulati and Anna McHugh and Anna Surridge and Annie Newby and Benjamin Brown and Benjamin Dowdell and Cecily Christopher and Chitra Garg and George Dykes and Hezekiah Awosusi and Ian J. Storey and Jake Taylor and James Newton and Jamie McPherson and Kirsty MacLeod and Laura Heggie and Maria Mazza and Martha Smith and Melissa Hartley and Nabeel Siddiqui and Natalie Hickling and Peter Bye and Tom E.F. Abbott and Basil Nourallah and Georgina Harridge and Lucy Stephenson and Jeveria Raja and Laura Fulton and Juri Althonayan and Omar S. Ghori and Adele Mazzoleni and Aleksander Lysomirski and Fariha Rehman and Greg Titterton and James Tavner and Panayiotis Stavrinou and Ron Thomas and Salma Begum and Sarah-Louise Watson and Tom E.F. Abbott and Jonathan G. Brend and Sukhmani Sra and Imran Ali and James Matthews and James Waiting and Michael Sawaryn and Adele Mazzoleni and Aleksander Lysomirski and Alexander Ka Jun Lee and Alexey Koroshilov and Dijay Dave and Evangelia Giannas and Fariha Rehman and Fatima Seidu and Greg Titterton and James Tavner and Juri Althonayan and Kavi Thobani and Ler Tu Seah and Mareena Joseph and Omar S. Ghori and Onika Ottley and Panayiotis Stavrinou and Rakshanda Mackay and Sarah-Louise Watson and Shreya Suresh and Sophie Arthur and Ron Thomas and Jai Vairale and Timothy Martin and Bhavesh C. Gohil and Anjali Char and Aderonke Adesanoye and Alice Gao and Eamon Dhall and Francis Elechi and Freddie Weyman and Deirdre Guerin and Harry Porter and James Lambert and Lynden Nicely and Michael Sawaryn and Ruth Parker and Louise Savic and Amy Longhurst and Anna Littlejohns and Beverley Jackson and Caroline Thomas and Catherine Moriarty and Chandan Gupta and Daniel Ruane and Jack Sherlock and Joe Gleeson-Buddhdev and Kapeel Dave and Lucy Marshall and Matthew Gowshall and Mohannad Mohyeldin and Nicholas Charlesworth and Nilmini Manawaduge and Samuel Flatau and Roshan S. Verghese and Vikas Kaura and Adam Neep and Anagha Joy and Ayman Salmona and Bridie O'neill and Chloe Uffendell and Dawne Conlon and Himani Pahuja and Holly Davies and Mark Priestley and Naina Stannard and Neha Hudlikar and Oliver Ross-Smith and Rachel Holmes and Rebecca King and Rosie Wragg and Komal Ray and Amelia Milton and Aneesha Qadeer and Emma Walshaw and John Paul and John Wylde and Judith Sharp and Kanmani T. Lakshmikantha and Kate Gallagher and Michelle Naylor and Samuel Craven and Sneha Raju and Tetiana Khinalska and Zahid Furqan and Mark R. Edwards and Norma Diaper and Alice Baker and Karen Salmon and Sara Navalesi and Missy Harrison and Katie Ayyash and Alison Cairns and Bryony Shelton and Hao Ming Kevin Cheung and Edward Kenny and Ioannis Panagopoulos and Naoroz Patell and Pallavi Thakare and Thin Swe and Amrinder Sayan and Jamie Gonzales and Tamas Szakmany and Aled Rees and Angharad King and Ashley Davies and Daniel Akintelure and Luke Agace and Mai Nur Sariah M. Nasser and Mary Perkins and Robert Yates and Chiraag Talati and Deborah Elf and Alexander Rossides and Naomi Watson and Debadutta Behera and Jumainah F. Rahman and Jacqueline Davies and Alex Bird and Jade Holmes and Joanne Arnold and Louise Savic},
year = {2026},
journal = {eClinicalMedicine},
doi = {10.1016/j.eclinm.2026.104151},
url = {https://doi.org/10.1016/j.eclinm.2026.104151}
}RIS
TY - JOUR TI - Safety of routine antimicrobial prophylaxis for surgery (SAPPHIRE): a prospective multi-centre cohort study AU - Tom E.F. Abbott AU - Priyanthi Dias AU - Jai Vairale AU - Salma Begum AU - Kamran Khan AU - Alexander J. Fowler AU - Vikas Kaura AU - Rupert M. Pearse AU - Tom E.F. Abbott AU - Priyanthi Dias AU - Salma Begum AU - Jai Vairale AU - Russ Hewson AU - Alex Fowler AU - Kamran Khan AU - Vikas Kaura AU - Rupert M. Pearse AU - Louise Savic AU - Louise Savic AU - Tom E.F. Abbott AU - Salma Begum AU - Priyanthi Dias AU - Kamran Khan AU - Vikas Kaura AU - Russell Hewson AU - Jai Vairale AU - Rupert M. Pearse AU - Tom E.F. Abbott AU - Louise Savic AU - Salma Begum AU - Priyanthi Dias AU - Alex Fowler AU - Vikas Kaura AU - Rupert M. Pearse AU - Robert Lewis AU - Tracy Griffiths AU - Aashima Bakshi AU - Katrina Cooke AU - Chiara De Leonardis AU - Edyta Klata AU - Emma Williams AU - Kerry Smith AU - Michelle Dotchin AU - Robert Lewis AU - Vanessa Rivers AU - Caitlin Palmer AU - Natalie Keenan AU - Christine Hibbert AU - Helen Wassall AU - Jan Tomkinson AU - Joanne Bradley-Potts AU - Katherine Rose AU - Philippa Hill AU - Sarah Ward AU - Hannah Brennan AU - Mohamed Mahmoud AU - Brendan Sloan AU - Mark Southworth AU - Anna Littlejohns AU - Daniel Thomas AU - Diana Kluczna AU - Nicholas Wroe AU - Tracy Langcake AU - James Roden AU - Chun Chiu AU - Jordon Almas AU - Matthew Howe AU - Rachel Murali-Krishnan AU - Sarah Buckley AU - Elizabeth Denis AU - Thelma Darian AU - Alexandra Metcalfe AU - Amy Major AU - Abigail Crew AU - Ronelle Mouton AU - Amy Dodd AU - Alexander Ferriman AU - Carmel Oliver AU - Edward Mew AU - Kate Skidmore AU - Kat Herneman AU - Richard Elston AU - Stella Arthur Quarm AU - Timothy Walker AU - Gayani Jayasooriya AU - William Turner AU - Sejung Park AU - Isabel Bradley AU - Ramy Mahmoud AU - Sunitha Eswarappa AU - Roshni Molls AU - Amanda Davis AU - Judith Bradley AU - Margaret Grout AU - Jackie Latimer AU - Muqsith Rasool AU - Aparna George AU - George Joseph AU - Soumyajit Saha AU - Tatiana Pogreban AU - Toko Akangadjo AU - Mohammed Sabihul Islam AU - Sanjay K. Sakholiya AU - Amila Herath AU - Marvin Mutebi AU - Christopher Marsh AU - Alison Kirby AU - Andrew Ike AU - Annette Moreton AU - Catherine Bressington AU - Jenny Pullen AU - Jessica Sellick AU - Lowri Jones AU - Nora Seager-Wilkendorf AU - Ros Knight AU - Rose Warren AU - Sara Burnard AU - Spandana Gumpula AU - Wendy Duberry AU - Shaman Jhanji AU - Holly Townsend-Renn AU - Anna Warrington AU - David Parkinson AU - Ethel Black AU - Holly Hogan AU - Imran Ali AU - Maxime Caron-Goudreau AU - Kayleigh Jessop AU - Samantha Black AU - Dilukshi Wickramasinghe AU - Linda Ofori AU - Lisa Parker AU - Patience Nkala AU - Thomas Gower AU - Tom Hatton AU - Trudi Chronnell AU - Sam Martin AU - George Clews AU - Victoria Ewasiuk AU - Anais Mutarambirwa AU - Clarissa Madla AU - Anil P. Hormis AU - Rachel Walker AU - Caroline Bird AU - Cheryl Graham AU - Laura Naish AU - Samuel Yale AU - Alasdair Sandland AU - Joyce Yeung AU - Helen Taylor AU - Jo Gresty AU - Juliet Sebastian AU - Mehwaish Zulfiqar AU - Meirvaan Basra AU - Fred Parker AU - Teresa Melody AU - Eleanor Reeves AU - Celina Maliaykal AU - Sundar Ashok AU - Cassandra George AU - Christopher Black AU - Islam Abousharkh AU - Layla Guscoth AU - Louise Phaure AU - Sophie Boles AU - Sreedevi Rajalingam AU - Rhona Sinclair AU - Iain J. McCullagh AU - Rikzing D. Bhutia AU - Sabrina Kapur AU - Wendell Storr AU - Adam Cookson AU - Adam Mowatt AU - Alex Wilson AU - Arti Gulati AU - Anna McHugh AU - Anna Surridge AU - Annie Newby AU - Benjamin Brown AU - Benjamin Dowdell AU - Cecily Christopher AU - Chitra Garg AU - George Dykes AU - Hezekiah Awosusi AU - Ian J. Storey AU - Jake Taylor AU - James Newton AU - Jamie McPherson AU - Kirsty MacLeod AU - Laura Heggie AU - Maria Mazza AU - Martha Smith AU - Melissa Hartley AU - Nabeel Siddiqui AU - Natalie Hickling AU - Peter Bye AU - Tom E.F. Abbott AU - Basil Nourallah AU - Georgina Harridge AU - Lucy Stephenson AU - Jeveria Raja AU - Laura Fulton AU - Juri Althonayan AU - Omar S. Ghori AU - Adele Mazzoleni AU - Aleksander Lysomirski AU - Fariha Rehman AU - Greg Titterton AU - James Tavner AU - Panayiotis Stavrinou AU - Ron Thomas AU - Salma Begum AU - Sarah-Louise Watson AU - Tom E.F. Abbott AU - Jonathan G. Brend AU - Sukhmani Sra AU - Imran Ali AU - James Matthews AU - James Waiting AU - Michael Sawaryn AU - Adele Mazzoleni AU - Aleksander Lysomirski AU - Alexander Ka Jun Lee AU - Alexey Koroshilov AU - Dijay Dave AU - Evangelia Giannas AU - Fariha Rehman AU - Fatima Seidu AU - Greg Titterton AU - James Tavner AU - Juri Althonayan AU - Kavi Thobani AU - Ler Tu Seah AU - Mareena Joseph AU - Omar S. Ghori AU - Onika Ottley AU - Panayiotis Stavrinou AU - Rakshanda Mackay AU - Sarah-Louise Watson AU - Shreya Suresh AU - Sophie Arthur AU - Ron Thomas AU - Jai Vairale AU - Timothy Martin AU - Bhavesh C. Gohil AU - Anjali Char AU - Aderonke Adesanoye AU - Alice Gao AU - Eamon Dhall AU - Francis Elechi AU - Freddie Weyman AU - Deirdre Guerin AU - Harry Porter AU - James Lambert AU - Lynden Nicely AU - Michael Sawaryn AU - Ruth Parker AU - Louise Savic AU - Amy Longhurst AU - Anna Littlejohns AU - Beverley Jackson AU - Caroline Thomas AU - Catherine Moriarty AU - Chandan Gupta AU - Daniel Ruane AU - Jack Sherlock AU - Joe Gleeson-Buddhdev AU - Kapeel Dave AU - Lucy Marshall AU - Matthew Gowshall AU - Mohannad Mohyeldin AU - Nicholas Charlesworth AU - Nilmini Manawaduge AU - Samuel Flatau AU - Roshan S. Verghese AU - Vikas Kaura AU - Adam Neep AU - Anagha Joy AU - Ayman Salmona AU - Bridie O'neill AU - Chloe Uffendell AU - Dawne Conlon AU - Himani Pahuja AU - Holly Davies AU - Mark Priestley AU - Naina Stannard AU - Neha Hudlikar AU - Oliver Ross-Smith AU - Rachel Holmes AU - Rebecca King AU - Rosie Wragg AU - Komal Ray AU - Amelia Milton AU - Aneesha Qadeer AU - Emma Walshaw AU - John Paul AU - John Wylde AU - Judith Sharp AU - Kanmani T. Lakshmikantha AU - Kate Gallagher AU - Michelle Naylor AU - Samuel Craven AU - Sneha Raju AU - Tetiana Khinalska AU - Zahid Furqan AU - Mark R. Edwards AU - Norma Diaper AU - Alice Baker AU - Karen Salmon AU - Sara Navalesi AU - Missy Harrison AU - Katie Ayyash AU - Alison Cairns AU - Bryony Shelton AU - Hao Ming Kevin Cheung AU - Edward Kenny AU - Ioannis Panagopoulos AU - Naoroz Patell AU - Pallavi Thakare AU - Thin Swe AU - Amrinder Sayan AU - Jamie Gonzales AU - Tamas Szakmany AU - Aled Rees AU - Angharad King AU - Ashley Davies AU - Daniel Akintelure AU - Luke Agace AU - Mai Nur Sariah M. Nasser AU - Mary Perkins AU - Robert Yates AU - Chiraag Talati AU - Deborah Elf AU - Alexander Rossides AU - Naomi Watson AU - Debadutta Behera AU - Jumainah F. Rahman AU - Jacqueline Davies AU - Alex Bird AU - Jade Holmes AU - Joanne Arnold AU - Louise Savic PY - 2026 JO - eClinicalMedicine DO - 10.1016/j.eclinm.2026.104151 UR - https://doi.org/10.1016/j.eclinm.2026.104151 ER -
APA
Abbott, T. E., Dias, P., Vairale, J., Begum, S., Khan, K., Fowler, A. J., Kaura, V., Pearse, R. M., Abbott, T. E., Dias, P., Begum, S., Vairale, J., Hewson, R., Fowler, A., Khan, K., Kaura, V., Pearse, R. M., Savic, L., Savic, L., Abbott, T. E., Begum, S., Dias, P., Khan, K., Kaura, V., Hewson, R., Vairale, J., Pearse, R. M., Abbott, T. E., Savic, L., Begum, S., Dias, P., Fowler, A., Kaura, V., Pearse, R. M., Lewis, R., Griffiths, T., Bakshi, A., Cooke, K., Leonardis, C. D., Klata, E., Williams, E., Smith, K., Dotchin, M., Lewis, R., Rivers, V., Palmer, C., Keenan, N., Hibbert, C., Wassall, H., Tomkinson, J., Bradley-Potts, J., Rose, K., Hill, P., Ward, S., Brennan, H., Mahmoud, M., Sloan, B., Southworth, M., Littlejohns, A., Thomas, D., Kluczna, D., Wroe, N., Langcake, T., Roden, J., Chiu, C., Almas, J., Howe, M., Murali-Krishnan, R., Buckley, S., Denis, E., Darian, T., Metcalfe, A., Major, A., Crew, A., Mouton, R., Dodd, A., Ferriman, A., Oliver, C., Mew, E., Skidmore, K., Herneman, K., Elston, R., Quarm, S. A., Walker, T., Jayasooriya, G., Turner, W., Park, S., Bradley, I., Mahmoud, R., Eswarappa, S., Molls, R., Davis, A., Bradley, J., Grout, M., Latimer, J., Rasool, M., George, A., Joseph, G., Saha, S., Pogreban, T., Akangadjo, T., Islam, M. S., Sakholiya, S. K., Herath, A., Mutebi, M., Marsh, C., Kirby, A., Ike, A., Moreton, A., Bressington, C., Pullen, J., Sellick, J., Jones, L., Seager-Wilkendorf, N., Knight, R., Warren, R., Burnard, S., Gumpula, S., Duberry, W., Jhanji, S., Townsend-Renn, H., Warrington, A., Parkinson, D., Black, E., Hogan, H., Ali, I., Caron-Goudreau, M., Jessop, K., Black, S., Wickramasinghe, D., Ofori, L., Parker, L., Nkala, P., Gower, T., Hatton, T., Chronnell, T., Martin, S., Clews, G., Ewasiuk, V., Mutarambirwa, A., Madla, C., Hormis, A. P., Walker, R., Bird, C., Graham, C., Naish, L., Yale, S., Sandland, A., Yeung, J., Taylor, H., Gresty, J., Sebastian, J., Zulfiqar, M., Basra, M., Parker, F., Melody, T., Reeves, E., Maliaykal, C., Ashok, S., George, C., Black, C., Abousharkh, I., Guscoth, L., Phaure, L., Boles, S., Rajalingam, S., Sinclair, R., McCullagh, I. J., Bhutia, R. D., Kapur, S., Storr, W., Cookson, A., Mowatt, A., Wilson, A., Gulati, A., McHugh, A., Surridge, A., Newby, A., Brown, B., Dowdell, B., Christopher, C., Garg, C., Dykes, G., Awosusi, H., Storey, I. J., Taylor, J., Newton, J., McPherson, J., MacLeod, K., Heggie, L., Mazza, M., Smith, M., Hartley, M., Siddiqui, N., Hickling, N., Bye, P., Abbott, T. E., Nourallah, B., Harridge, G., Stephenson, L., Raja, J., Fulton, L., Althonayan, J., Ghori, O. S., Mazzoleni, A., Lysomirski, A., Rehman, F., Titterton, G., Tavner, J., Stavrinou, P., Thomas, R., Begum, S., Watson, S., Abbott, T. E., Brend, J. G., Sra, S., Ali, I., Matthews, J., Waiting, J., Sawaryn, M., Mazzoleni, A., Lysomirski, A., Lee, A. K. J., Koroshilov, A., Dave, D., Giannas, E., Rehman, F., Seidu, F., Titterton, G., Tavner, J., Althonayan, J., Thobani, K., Seah, L. T., Joseph, M., Ghori, O. S., Ottley, O., Stavrinou, P., Mackay, R., Watson, S., Suresh, S., Arthur, S., Thomas, R., Vairale, J., Martin, T., Gohil, B. C., Char, A., Adesanoye, A., Gao, A., Dhall, E., Elechi, F., Weyman, F., Guerin, D., Porter, H., Lambert, J., Nicely, L., Sawaryn, M., Parker, R., Savic, L., Longhurst, A., Littlejohns, A., Jackson, B., Thomas, C., Moriarty, C., Gupta, C., Ruane, D., Sherlock, J., Gleeson-Buddhdev, J., Dave, K., Marshall, L., Gowshall, M., Mohyeldin, M., Charlesworth, N., Manawaduge, N., Flatau, S., Verghese, R. S., Kaura, V., Neep, A., Joy, A., Salmona, A., O'neill, B., Uffendell, C., Conlon, D., Pahuja, H., Davies, H., Priestley, M., Stannard, N., Hudlikar, N., Ross-Smith, O., Holmes, R., King, R., Wragg, R., Ray, K., Milton, A., Qadeer, A., Walshaw, E., Paul, J., Wylde, J., Sharp, J., Lakshmikantha, K. T., Gallagher, K., Naylor, M., Craven, S., Raju, S., Khinalska, T., Furqan, Z., Edwards, M. R., Diaper, N., Baker, A., Salmon, K., Navalesi, S., Harrison, M., Ayyash, K., Cairns, A., Shelton, B., Cheung, H. M. K., Kenny, E., Panagopoulos, I., Patell, N., Thakare, P., Swe, T., Sayan, A., Gonzales, J., Szakmany, T., Rees, A., King, A., Davies, A., Akintelure, D., Agace, L., Nasser, M. N. S. M., Perkins, M., Yates, R., Talati, C., Elf, D., Rossides, A., Watson, N., Behera, D., Rahman, J. F., Davies, J., Bird, A., Holmes, J., Arnold, J., & Savic, L. (2026). Safety of routine antimicrobial prophylaxis for surgery (SAPPHIRE): a prospective multi-centre cohort study. eClinicalMedicine. https://doi.org/10.1016/j.eclinm.2026.104151
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- crossref · retrieved 2026-09-25T06:09:20.620Z