Novel tacrine-based multi-target directed Ligands: Enhancing cholinesterase inhibition, NMDA receptor antagonism, and CNS bioavailability for Alzheimer's disease treatment.

Svobodova B, Moravcova Z, Misiachna A, Novakova G, Marek A, Finger V, Odvarkova J, Pejchal J, Karasova JZ, Netolicky J, Ladislav M, Hrabinova M, Sorf A, Muckova L, Fikejzlova L, Benkova M, Novak M, Prchal L, Capek J, Handl J, Rousar T, Greber KE, Ciura K, Horak M, Soukup O, Korabecny J.

Open source

DOI: 10.1016/j.ejmech.2025.117678
Published: 2025-04-22
Container: Eur J Med Chem
Publisher: Not recorded
Open access: no

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Cite this work

BibTeX

@article{allodium:10.1016/j.ejmech.2025.117678,
  title = {Novel tacrine-based multi-target directed Ligands: Enhancing cholinesterase inhibition, NMDA receptor antagonism, and CNS bioavailability for Alzheimer's disease treatment.},
  author = {Svobodova B and  Moravcova Z and  Misiachna A and  Novakova G and  Marek A and  Finger V and  Odvarkova J and  Pejchal J and  Karasova JZ and  Netolicky J and  Ladislav M and  Hrabinova M and  Sorf A and  Muckova L and  Fikejzlova L and  Benkova M and  Novak M and  Prchal L and  Capek J and  Handl J and  Rousar T and  Greber KE and  Ciura K and  Horak M and  Soukup O and  Korabecny J.},
  year = {2025},
  journal = {Eur J Med Chem},
  doi = {10.1016/j.ejmech.2025.117678},
  url = {https://doi.org/10.1016/j.ejmech.2025.117678}
}

RIS

TY  - JOUR
TI  - Novel tacrine-based multi-target directed Ligands: Enhancing cholinesterase inhibition, NMDA receptor antagonism, and CNS bioavailability for Alzheimer's disease treatment.
AU  - Svobodova B
AU  -  Moravcova Z
AU  -  Misiachna A
AU  -  Novakova G
AU  -  Marek A
AU  -  Finger V
AU  -  Odvarkova J
AU  -  Pejchal J
AU  -  Karasova JZ
AU  -  Netolicky J
AU  -  Ladislav M
AU  -  Hrabinova M
AU  -  Sorf A
AU  -  Muckova L
AU  -  Fikejzlova L
AU  -  Benkova M
AU  -  Novak M
AU  -  Prchal L
AU  -  Capek J
AU  -  Handl J
AU  -  Rousar T
AU  -  Greber KE
AU  -  Ciura K
AU  -  Horak M
AU  -  Soukup O
AU  -  Korabecny J.
PY  - 2025
JO  - Eur J Med Chem
DO  - 10.1016/j.ejmech.2025.117678
UR  - https://doi.org/10.1016/j.ejmech.2025.117678
ER  -

APA

B, S., Z, M., A, M., G, N., A, M., V, F., J, O., J, P., JZ, K., J, N., M, L., M, H., A, S., L, M., L, F., M, B., M, N., L, P., J, C., J, H., T, R., KE, G., K, C., M, H., O, S., & J., K. (2025). Novel tacrine-based multi-target directed Ligands: Enhancing cholinesterase inhibition, NMDA receptor antagonism, and CNS bioavailability for Alzheimer's disease treatment.. Eur J Med Chem. https://doi.org/10.1016/j.ejmech.2025.117678

Source records

europe-pmc · retrieved 2026-09-25T20:05:11.253Z