Discovery of an efficacious 2-ethyl-4-phenylthiazole derivative against acute Chagas disease via multiparametric hit-to-lead optimization and in vivo efficacy.
- DOI
- 10.1016/j.ejmech.2026.118888
- Published
- 2026-04-28
- Container
- Eur J Med Chem
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- Not recorded
- Open access
- no
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Cite this work
BibTeX
@article{allodium:10.1016/j.ejmech.2026.118888,
title = {Discovery of an efficacious 2-ethyl-4-phenylthiazole derivative against acute Chagas disease via multiparametric hit-to-lead optimization and in vivo efficacy.},
author = {Dit Lapierre TJWJ and Resende DM and de Melo FDSM and Carvalho AMDS and Oliveira DDDS and Michelan-Duarte S and Chelucci RC and Macruz PD and Diniz LA and Ferreira RS and Continentino AL and Moreira GLDS and Xavier ÍLDS and Longo JPF and Calvet CM and Pilau EJ and Ferreira LLG and Andricopulo AD and Neves BJ and Murta SMF and Bastos IMD and Júnior COR.},
year = {2026},
journal = {Eur J Med Chem},
doi = {10.1016/j.ejmech.2026.118888},
url = {https://doi.org/10.1016/j.ejmech.2026.118888}
}RIS
TY - JOUR TI - Discovery of an efficacious 2-ethyl-4-phenylthiazole derivative against acute Chagas disease via multiparametric hit-to-lead optimization and in vivo efficacy. AU - Dit Lapierre TJWJ AU - Resende DM AU - de Melo FDSM AU - Carvalho AMDS AU - Oliveira DDDS AU - Michelan-Duarte S AU - Chelucci RC AU - Macruz PD AU - Diniz LA AU - Ferreira RS AU - Continentino AL AU - Moreira GLDS AU - Xavier ÍLDS AU - Longo JPF AU - Calvet CM AU - Pilau EJ AU - Ferreira LLG AU - Andricopulo AD AU - Neves BJ AU - Murta SMF AU - Bastos IMD AU - Júnior COR. PY - 2026 JO - Eur J Med Chem DO - 10.1016/j.ejmech.2026.118888 UR - https://doi.org/10.1016/j.ejmech.2026.118888 ER -
APA
TJWJ, D. L., DM, R., FDSM, D. M., AMDS, C., DDDS, O., S, M., RC, C., PD, M., LA, D., RS, F., AL, C., GLDS, M., ÍLDS, X., JPF, L., CM, C., EJ, P., LLG, F., AD, A., BJ, N., SMF, M., IMD, B., & COR., J. (2026). Discovery of an efficacious 2-ethyl-4-phenylthiazole derivative against acute Chagas disease via multiparametric hit-to-lead optimization and in vivo efficacy.. Eur J Med Chem. https://doi.org/10.1016/j.ejmech.2026.118888
Source records
- europe-pmc · retrieved 2026-09-26T12:55:14.412Z