Design, synthesis and evaluation of an uncharged broad spectrum quinoline-oxime hybrid for the reactivation of nerve agent-inhibited human acetylcholinesterase

Julien De Sousa, André-Guilhem Calas, Eugenio De La Mora, Christophe Landry, Anne-Sophie Hanak, Alex Maryan-Instone, Anne-Julie Gastellier, Caroline Coisne, Charlotte Courageux, Johan Hachani, Fabien Gosselet, Marie-Pierre Dehouck, Catherine Rousseau, Christopher M. Timperley, Martin Weik, Florian Nachon, Richard C.D. Brown, Rachid Baati, José Dias

Open source

DOI
10.1016/j.ejmech.2026.119023
Published
2026-10
Container
European Journal of Medicinal Chemistry
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/j.ejmech.2026.119023,
  title = {Design, synthesis and evaluation of an uncharged broad spectrum quinoline-oxime hybrid for the reactivation of nerve agent-inhibited human acetylcholinesterase},
  author = {Julien De Sousa and André-Guilhem Calas and Eugenio De La Mora and Christophe Landry and Anne-Sophie Hanak and Alex Maryan-Instone and Anne-Julie Gastellier and Caroline Coisne and Charlotte Courageux and Johan Hachani and Fabien Gosselet and Marie-Pierre Dehouck and Catherine Rousseau and Christopher M. Timperley and Martin Weik and Florian Nachon and Richard C.D. Brown and Rachid Baati and José Dias},
  year = {2026},
  journal = {European Journal of Medicinal Chemistry},
  doi = {10.1016/j.ejmech.2026.119023},
  url = {https://doi.org/10.1016/j.ejmech.2026.119023}
}

RIS

TY  - JOUR
TI  - Design, synthesis and evaluation of an uncharged broad spectrum quinoline-oxime hybrid for the reactivation of nerve agent-inhibited human acetylcholinesterase
AU  - Julien De Sousa
AU  - André-Guilhem Calas
AU  - Eugenio De La Mora
AU  - Christophe Landry
AU  - Anne-Sophie Hanak
AU  - Alex Maryan-Instone
AU  - Anne-Julie Gastellier
AU  - Caroline Coisne
AU  - Charlotte Courageux
AU  - Johan Hachani
AU  - Fabien Gosselet
AU  - Marie-Pierre Dehouck
AU  - Catherine Rousseau
AU  - Christopher M. Timperley
AU  - Martin Weik
AU  - Florian Nachon
AU  - Richard C.D. Brown
AU  - Rachid Baati
AU  - José Dias
PY  - 2026
JO  - European Journal of Medicinal Chemistry
DO  - 10.1016/j.ejmech.2026.119023
UR  - https://doi.org/10.1016/j.ejmech.2026.119023
ER  - 

APA

Sousa, J. D., Calas, A., Mora, E. D. L., Landry, C., Hanak, A., Maryan-Instone, A., Gastellier, A., Coisne, C., Courageux, C., Hachani, J., Gosselet, F., Dehouck, M., Rousseau, C., Timperley, C. M., Weik, M., Nachon, F., Brown, R. C., Baati, R., & Dias, J. (2026). Design, synthesis and evaluation of an uncharged broad spectrum quinoline-oxime hybrid for the reactivation of nerve agent-inhibited human acetylcholinesterase. European Journal of Medicinal Chemistry. https://doi.org/10.1016/j.ejmech.2026.119023

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