Exploring the role of conformational restriction in 5-alkyl-6-benzyl-2-{[(methylthio)methyl]thio}pyrimidin-4(3H)-ones: Effects in HIV-1 infected cells and reverse transcriptase enzymes

Egor Degtyarenko, Gebremedhin Solomon Hailu, Emanuele Fabbrizi, Anastasia Golovina, Andrey Voronkov, Roberta Astolfi, Lidia Giuliani, Andrea Mancini, Maxim B. Nawrozkij, Vladimir Chernyshov, Clarissa Pupillo, Roberto Cirilli, Laura Bavagnoli, Rino Ragno, José A. Esté, Emmanuele Crespan, Francesco Fiorentino, Roman Ivanov, Antonello Mai, Dante Rotili

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DOI: 10.1016/j.ejmech.2026.119304
Published: 2026-12
Container: European Journal of Medicinal Chemistry
Publisher: Elsevier BV
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1016/j.ejmech.2026.119304,
  title = {Exploring the role of conformational restriction in 5-alkyl-6-benzyl-2-\{[(methylthio)methyl]thio\}pyrimidin-4(3H)-ones: Effects in HIV-1 infected cells and reverse transcriptase enzymes},
  author = {Egor Degtyarenko and Gebremedhin Solomon Hailu and Emanuele Fabbrizi and Anastasia Golovina and Andrey Voronkov and Roberta Astolfi and Lidia Giuliani and Andrea Mancini and Maxim B. Nawrozkij and Vladimir Chernyshov and Clarissa Pupillo and Roberto Cirilli and Laura Bavagnoli and Rino Ragno and José A. Esté and Emmanuele Crespan and Francesco Fiorentino and Roman Ivanov and Antonello Mai and Dante Rotili},
  year = {2026},
  journal = {European Journal of Medicinal Chemistry},
  doi = {10.1016/j.ejmech.2026.119304},
  url = {https://doi.org/10.1016/j.ejmech.2026.119304}
}

RIS

TY  - JOUR
TI  - Exploring the role of conformational restriction in 5-alkyl-6-benzyl-2-{[(methylthio)methyl]thio}pyrimidin-4(3H)-ones: Effects in HIV-1 infected cells and reverse transcriptase enzymes
AU  - Egor Degtyarenko
AU  - Gebremedhin Solomon Hailu
AU  - Emanuele Fabbrizi
AU  - Anastasia Golovina
AU  - Andrey Voronkov
AU  - Roberta Astolfi
AU  - Lidia Giuliani
AU  - Andrea Mancini
AU  - Maxim B. Nawrozkij
AU  - Vladimir Chernyshov
AU  - Clarissa Pupillo
AU  - Roberto Cirilli
AU  - Laura Bavagnoli
AU  - Rino Ragno
AU  - José A. Esté
AU  - Emmanuele Crespan
AU  - Francesco Fiorentino
AU  - Roman Ivanov
AU  - Antonello Mai
AU  - Dante Rotili
PY  - 2026
JO  - European Journal of Medicinal Chemistry
DO  - 10.1016/j.ejmech.2026.119304
UR  - https://doi.org/10.1016/j.ejmech.2026.119304
ER  -

APA

Degtyarenko, E., Hailu, G. S., Fabbrizi, E., Golovina, A., Voronkov, A., Astolfi, R., Giuliani, L., Mancini, A., Nawrozkij, M. B., Chernyshov, V., Pupillo, C., Cirilli, R., Bavagnoli, L., Ragno, R., Esté, J. A., Crespan, E., Fiorentino, F., Ivanov, R., Mai, A., & Rotili, D. (2026). Exploring the role of conformational restriction in 5-alkyl-6-benzyl-2-{[(methylthio)methyl]thio}pyrimidin-4(3H)-ones: Effects in HIV-1 infected cells and reverse transcriptase enzymes. European Journal of Medicinal Chemistry. https://doi.org/10.1016/j.ejmech.2026.119304

Source records

crossref · retrieved 2026-09-25T21:20:14.550Z