Direct-to-biology high-throughput optimization enables rapid hit-to-lead discovery of potent CDK2 inhibitors

Huanmin Zhou, Zhidi Chen, Qingcheng Huang, Peijuan Chen, Yizhou Bian, Yu Wang, Yonghao Lin, Xiaozhen Zheng, Junyi Qiu, Xin Lu, Shuiping Fu, Shijie Chen, Dongxiang Liu, Cheng Luo, Ge Sun, Jin Lin

Open source

DOI
10.1016/j.ejmech.2026.119490
Published
2027-01
Container
European Journal of Medicinal Chemistry
Publisher
Elsevier BV
Open access
unknown

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Cite this work

BibTeX

@article{allodium:10.1016/j.ejmech.2026.119490,
  title = {Direct-to-biology high-throughput optimization enables rapid hit-to-lead discovery of potent CDK2 inhibitors},
  author = {Huanmin Zhou and Zhidi Chen and Qingcheng Huang and Peijuan Chen and Yizhou Bian and Yu Wang and Yonghao Lin and Xiaozhen Zheng and Junyi Qiu and Xin Lu and Shuiping Fu and Shijie Chen and Dongxiang Liu and Cheng Luo and Ge Sun and Jin Lin},
  year = {2027},
  journal = {European Journal of Medicinal Chemistry},
  doi = {10.1016/j.ejmech.2026.119490},
  url = {https://doi.org/10.1016/j.ejmech.2026.119490}
}

RIS

TY  - JOUR
TI  - Direct-to-biology high-throughput optimization enables rapid hit-to-lead discovery of potent CDK2 inhibitors
AU  - Huanmin Zhou
AU  - Zhidi Chen
AU  - Qingcheng Huang
AU  - Peijuan Chen
AU  - Yizhou Bian
AU  - Yu Wang
AU  - Yonghao Lin
AU  - Xiaozhen Zheng
AU  - Junyi Qiu
AU  - Xin Lu
AU  - Shuiping Fu
AU  - Shijie Chen
AU  - Dongxiang Liu
AU  - Cheng Luo
AU  - Ge Sun
AU  - Jin Lin
PY  - 2027
JO  - European Journal of Medicinal Chemistry
DO  - 10.1016/j.ejmech.2026.119490
UR  - https://doi.org/10.1016/j.ejmech.2026.119490
ER  - 

APA

Zhou, H., Chen, Z., Huang, Q., Chen, P., Bian, Y., Wang, Y., Lin, Y., Zheng, X., Qiu, J., Lu, X., Fu, S., Chen, S., Liu, D., Luo, C., Sun, G., & Lin, J. (2027). Direct-to-biology high-throughput optimization enables rapid hit-to-lead discovery of potent CDK2 inhibitors. European Journal of Medicinal Chemistry. https://doi.org/10.1016/j.ejmech.2026.119490

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