Therapeutic potential of nicorandil vs nebivolol in attenuating PKC/P38MAPK signaling via PPARγ/KLOTHO/CREB pathway signaling: molecular docking and experimental validation in rat model of unilateral ureteric obstruction

Amira Karam Khalifa, Amr M. Galal, Sameh Saber, Ahmed F. El-Sayed, Aishah M. Alsibaee, Tahani Saeedi, Samia Alsubhi, Samar F. Miski, Basma Emad Aboulhoda, Eman Emad Eldin Mohamed, Hanaa Wanas

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DOI: 10.1016/j.ejphar.2026.178962
Published: 2026-06
Container: European Journal of Pharmacology
Publisher: Elsevier BV
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1016/j.ejphar.2026.178962,
  title = {Therapeutic potential of nicorandil vs nebivolol in attenuating PKC/P38MAPK signaling via PPARγ/KLOTHO/CREB pathway signaling: molecular docking and experimental validation in rat model of unilateral ureteric obstruction},
  author = {Amira Karam Khalifa and Amr M. Galal and Sameh Saber and Ahmed F. El-Sayed and Aishah M. Alsibaee and Tahani Saeedi and Samia Alsubhi and Samar F. Miski and Basma Emad Aboulhoda and Eman Emad Eldin Mohamed and Hanaa Wanas},
  year = {2026},
  journal = {European Journal of Pharmacology},
  doi = {10.1016/j.ejphar.2026.178962},
  url = {https://doi.org/10.1016/j.ejphar.2026.178962}
}

RIS

TY  - JOUR
TI  - Therapeutic potential of nicorandil vs nebivolol in attenuating PKC/P38MAPK signaling via PPARγ/KLOTHO/CREB pathway signaling: molecular docking and experimental validation in rat model of unilateral ureteric obstruction
AU  - Amira Karam Khalifa
AU  - Amr M. Galal
AU  - Sameh Saber
AU  - Ahmed F. El-Sayed
AU  - Aishah M. Alsibaee
AU  - Tahani Saeedi
AU  - Samia Alsubhi
AU  - Samar F. Miski
AU  - Basma Emad Aboulhoda
AU  - Eman Emad Eldin Mohamed
AU  - Hanaa Wanas
PY  - 2026
JO  - European Journal of Pharmacology
DO  - 10.1016/j.ejphar.2026.178962
UR  - https://doi.org/10.1016/j.ejphar.2026.178962
ER  -

APA

Khalifa, A. K., Galal, A. M., Saber, S., El-Sayed, A. F., Alsibaee, A. M., Saeedi, T., Alsubhi, S., Miski, S. F., Aboulhoda, B. E., Mohamed, E. E. E., & Wanas, H. (2026). Therapeutic potential of nicorandil vs nebivolol in attenuating PKC/P38MAPK signaling via PPARγ/KLOTHO/CREB pathway signaling: molecular docking and experimental validation in rat model of unilateral ureteric obstruction. European Journal of Pharmacology. https://doi.org/10.1016/j.ejphar.2026.178962

Source records

crossref · retrieved 2026-09-27T00:17:59.044Z