Predictive biomarkers for cetuximab-based rechallenge therapy in metastatic colorectal cancer: a pooled analysis of the CAVE and CAVE-2 GOIM studies.

Ciardiello D, Martini G, Pietrantonio F, Avallone A, Pisconti S, Santabarbara G, Latiano TP, Tortora G, Sartore-Bianchi A, Cremolini C, Messina M, Zampino MG, Foltran L, Pinto C, Zaniboni A, Antonuzzo L, Normanno N, Berardi R, Cogoni A, Lotesoriere C, Bordonaro R, Boscolo Bielo L, Curigliano G, Manca P, Leone AG, De Stefano A, Nisi C, Rossini D, Salvatore L, Maiello E, Siena S, Troiani T, De Vita F, Fazio N, Martinelli E, Ciardiello F, Napolitano S

Open source

DOI: 10.1016/j.esmogo.2026.100398
Published: 2026 Sep
Container: ESMO gastrointestinal oncology
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1016/j.esmogo.2026.100398,
  title = {Predictive biomarkers for cetuximab-based rechallenge therapy in metastatic colorectal cancer: a pooled analysis of the CAVE and CAVE-2 GOIM studies.},
  author = {Ciardiello D and Martini G and Pietrantonio F and Avallone A and Pisconti S and Santabarbara G and Latiano TP and Tortora G and Sartore-Bianchi A and Cremolini C and Messina M and Zampino MG and Foltran L and Pinto C and Zaniboni A and Antonuzzo L and Normanno N and Berardi R and Cogoni A and Lotesoriere C and Bordonaro R and Boscolo Bielo L and Curigliano G and Manca P and Leone AG and De Stefano A and Nisi C and Rossini D and Salvatore L and Maiello E and Siena S and Troiani T and De Vita F and Fazio N and Martinelli E and Ciardiello F and Napolitano S},
  year = {2026},
  journal = {ESMO gastrointestinal oncology},
  doi = {10.1016/j.esmogo.2026.100398},
  url = {https://doi.org/10.1016/j.esmogo.2026.100398}
}

RIS

TY  - JOUR
TI  - Predictive biomarkers for cetuximab-based rechallenge therapy in metastatic colorectal cancer: a pooled analysis of the CAVE and CAVE-2 GOIM studies.
AU  - Ciardiello D
AU  - Martini G
AU  - Pietrantonio F
AU  - Avallone A
AU  - Pisconti S
AU  - Santabarbara G
AU  - Latiano TP
AU  - Tortora G
AU  - Sartore-Bianchi A
AU  - Cremolini C
AU  - Messina M
AU  - Zampino MG
AU  - Foltran L
AU  - Pinto C
AU  - Zaniboni A
AU  - Antonuzzo L
AU  - Normanno N
AU  - Berardi R
AU  - Cogoni A
AU  - Lotesoriere C
AU  - Bordonaro R
AU  - Boscolo Bielo L
AU  - Curigliano G
AU  - Manca P
AU  - Leone AG
AU  - De Stefano A
AU  - Nisi C
AU  - Rossini D
AU  - Salvatore L
AU  - Maiello E
AU  - Siena S
AU  - Troiani T
AU  - De Vita F
AU  - Fazio N
AU  - Martinelli E
AU  - Ciardiello F
AU  - Napolitano S
PY  - 2026
JO  - ESMO gastrointestinal oncology
DO  - 10.1016/j.esmogo.2026.100398
UR  - https://doi.org/10.1016/j.esmogo.2026.100398
ER  -

APA

D, C., G, M., F, P., A, A., S, P., G, S., TP, L., G, T., A, S., C, C., M, M., MG, Z., L, F., C, P., A, Z., L, A., N, N., R, B., A, C., C, L., R, B., L, B. B., G, C., P, M., AG, L., A, D. S., C, N., D, R., L, S., E, M., S, S., T, T., F, D. V., N, F., E, M., F, C., & S, N. (2026). Predictive biomarkers for cetuximab-based rechallenge therapy in metastatic colorectal cancer: a pooled analysis of the CAVE and CAVE-2 GOIM studies.. ESMO gastrointestinal oncology. https://doi.org/10.1016/j.esmogo.2026.100398

Source records

pubmed · retrieved 2026-09-26T03:28:56.501Z