Progranulin deficiency in the brain activates an insulin signaling pathway that may promote neurodegeneration.
- DOI
- 10.1016/j.isci.2026.115720
- Published
- 2026 May 15
- Container
- iScience
- Publisher
- Not recorded
- Open access
- yes
Credibility signals
limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.
Show all credibility signals
- cautionDOI registered: No matching Crossref record was present in this response.
- cautionDOI resolves: No matching Crossref record was present in this response.
- not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility.
- not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made.
- not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made.
- not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made.
- not scoredROR affiliation: Not checked or no result supplied; no credibility inference made.
- not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- supportingOpen access status: Normalized open-access status: open.
- not scoredPublication license: Not checked or no result supplied; no credibility inference made.
- not scoredPublication version: A publication version was supplied but is not scored.
- cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty.
Cite this work
BibTeX
@article{allodium:10.1016/j.isci.2026.115720,
title = {Progranulin deficiency in the brain activates an insulin signaling pathway that may promote neurodegeneration.},
author = {Sajan MP and Aggarwal G and Hwang JJ and Smith DM and Cooper DR and Duncan MA and Hansen BC and Nguyen AD and Farese RV},
year = {2026},
journal = {iScience},
doi = {10.1016/j.isci.2026.115720},
url = {https://doi.org/10.1016/j.isci.2026.115720}
}RIS
TY - JOUR TI - Progranulin deficiency in the brain activates an insulin signaling pathway that may promote neurodegeneration. AU - Sajan MP AU - Aggarwal G AU - Hwang JJ AU - Smith DM AU - Cooper DR AU - Duncan MA AU - Hansen BC AU - Nguyen AD AU - Farese RV PY - 2026 JO - iScience DO - 10.1016/j.isci.2026.115720 UR - https://doi.org/10.1016/j.isci.2026.115720 ER -
APA
MP, S., G, A., JJ, H., DM, S., DR, C., MA, D., BC, H., AD, N., & RV, F. (2026). Progranulin deficiency in the brain activates an insulin signaling pathway that may promote neurodegeneration.. iScience. https://doi.org/10.1016/j.isci.2026.115720
Source records
- pubmed · retrieved 2026-09-25T14:45:26.161Z