Intestinal epithelial Casd1 regulates mucus sialic acid O-acetylation and limits tissue damage from large-intestinal mucosal insults

Simin Jafaripour, Mackenzie Melvin, Megan Turluk, Emily Howard, Noah Fancy, Madison Schwagele, Hongyuan Zhang, Jackline D.W. Irungu, Brian R. Wasik, Daniel Chou, Benjamin Bigiremana, Nitin, Caixia Ma, Qiaochu Liang, Negin Kazemian, Clara A. Letef, Sanjoy Ghosh, Sepideh Pakpour, Colin R. Parrish, Bruce A. Vallance, Wesley F. Zandberg, Kirk S.B. Bergstrom

Open source

DOI: 10.1016/j.isci.2026.117978
Published: 2026-11
Container: iScience
Publisher: Elsevier BV
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1016/j.isci.2026.117978,
  title = {Intestinal epithelial Casd1 regulates mucus sialic acid O-acetylation and limits tissue damage from large-intestinal mucosal insults},
  author = {Simin Jafaripour and Mackenzie Melvin and Megan Turluk and Emily Howard and Noah Fancy and Madison Schwagele and Hongyuan Zhang and Jackline D.W. Irungu and Brian R. Wasik and Daniel Chou and Benjamin Bigiremana and Nitin and Caixia Ma and Qiaochu Liang and Negin Kazemian and Clara A. Letef and Sanjoy Ghosh and Sepideh Pakpour and Colin R. Parrish and Bruce A. Vallance and Wesley F. Zandberg and Kirk S.B. Bergstrom},
  year = {2026},
  journal = {iScience},
  doi = {10.1016/j.isci.2026.117978},
  url = {https://doi.org/10.1016/j.isci.2026.117978}
}

RIS

TY  - JOUR
TI  - Intestinal epithelial Casd1 regulates mucus sialic acid O-acetylation and limits tissue damage from large-intestinal mucosal insults
AU  - Simin Jafaripour
AU  - Mackenzie Melvin
AU  - Megan Turluk
AU  - Emily Howard
AU  - Noah Fancy
AU  - Madison Schwagele
AU  - Hongyuan Zhang
AU  - Jackline D.W. Irungu
AU  - Brian R. Wasik
AU  - Daniel Chou
AU  - Benjamin Bigiremana
AU  - Nitin
AU  - Caixia Ma
AU  - Qiaochu Liang
AU  - Negin Kazemian
AU  - Clara A. Letef
AU  - Sanjoy Ghosh
AU  - Sepideh Pakpour
AU  - Colin R. Parrish
AU  - Bruce A. Vallance
AU  - Wesley F. Zandberg
AU  - Kirk S.B. Bergstrom
PY  - 2026
JO  - iScience
DO  - 10.1016/j.isci.2026.117978
UR  - https://doi.org/10.1016/j.isci.2026.117978
ER  -

APA

Jafaripour, S., Melvin, M., Turluk, M., Howard, E., Fancy, N., Schwagele, M., Zhang, H., Irungu, J. D., Wasik, B. R., Chou, D., Bigiremana, B., Nitin, Ma, C., Liang, Q., Kazemian, N., Letef, C. A., Ghosh, S., Pakpour, S., Parrish, C. R., Vallance, B. A., Zandberg, W. F., & Bergstrom, K. S. (2026). Intestinal epithelial Casd1 regulates mucus sialic acid O-acetylation and limits tissue damage from large-intestinal mucosal insults. iScience. https://doi.org/10.1016/j.isci.2026.117978

Source records

crossref · retrieved 2026-11-08T06:37:40.897Z