Highly selective, allosteric inhibition of TYK2 with oral ESK-001 in patients with moderate-to-severe plaque psoriasis: Results from STRIDE, a 12-week, randomized, double-blinded, placebo-controlled, dose-ranging phase 2 study

Andrew Blauvelt, Petr Arenberger, Maxwell B. Sauder, Megan Couvillion, Roman G. Rubio, Nicholas E. Vlahakis, Sibel Ucpinar, Grace Ma, Elena Hitraya, Mera K. Tilley, Kim A. Papp

Open source

DOI
10.1016/j.jaad.2025.07.013
Published
2026-01
Container
Journal of the American Academy of Dermatology
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/j.jaad.2025.07.013,
  title = {Highly selective, allosteric inhibition of TYK2 with oral ESK-001 in patients with moderate-to-severe plaque psoriasis: Results from STRIDE, a 12-week, randomized, double-blinded, placebo-controlled, dose-ranging phase 2 study},
  author = {Andrew Blauvelt and Petr Arenberger and Maxwell B. Sauder and Megan Couvillion and Roman G. Rubio and Nicholas E. Vlahakis and Sibel Ucpinar and Grace Ma and Elena Hitraya and Mera K. Tilley and Kim A. Papp},
  year = {2026},
  journal = {Journal of the American Academy of Dermatology},
  doi = {10.1016/j.jaad.2025.07.013},
  url = {https://doi.org/10.1016/j.jaad.2025.07.013}
}

RIS

TY  - JOUR
TI  - Highly selective, allosteric inhibition of TYK2 with oral ESK-001 in patients with moderate-to-severe plaque psoriasis: Results from STRIDE, a 12-week, randomized, double-blinded, placebo-controlled, dose-ranging phase 2 study
AU  - Andrew Blauvelt
AU  - Petr Arenberger
AU  - Maxwell B. Sauder
AU  - Megan Couvillion
AU  - Roman G. Rubio
AU  - Nicholas E. Vlahakis
AU  - Sibel Ucpinar
AU  - Grace Ma
AU  - Elena Hitraya
AU  - Mera K. Tilley
AU  - Kim A. Papp
PY  - 2026
JO  - Journal of the American Academy of Dermatology
DO  - 10.1016/j.jaad.2025.07.013
UR  - https://doi.org/10.1016/j.jaad.2025.07.013
ER  - 

APA

Blauvelt, A., Arenberger, P., Sauder, M. B., Couvillion, M., Rubio, R. G., Vlahakis, N. E., Ucpinar, S., Ma, G., Hitraya, E., Tilley, M. K., & Papp, K. A. (2026). Highly selective, allosteric inhibition of TYK2 with oral ESK-001 in patients with moderate-to-severe plaque psoriasis: Results from STRIDE, a 12-week, randomized, double-blinded, placebo-controlled, dose-ranging phase 2 study. Journal of the American Academy of Dermatology. https://doi.org/10.1016/j.jaad.2025.07.013

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