Structural basis of phospholipid sensing nuclear receptor LRH-1 recognition by carboxylic acid bioisosteres reveals an alternative ligand interaction site

Debipreeta Bhowmik, Michael L. Cato, Sarah M. Abraham, Racheal M. Spurlin, Autumn R. Flynn, Jennifer K. Colucci, Suzanne Mays, Emma H. D’Agostino, Alyssa M. Johnson, Nathan T. Jui, John Calvert, Eric A. Ortlund

Open source

DOI
10.1016/j.jbc.2026.113731
Published
2026-11
Container
Journal of Biological Chemistry
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/j.jbc.2026.113731,
  title = {Structural basis of phospholipid sensing nuclear receptor LRH-1 recognition by carboxylic acid bioisosteres reveals an alternative ligand interaction site},
  author = {Debipreeta Bhowmik and Michael L. Cato and Sarah M. Abraham and Racheal M. Spurlin and Autumn R. Flynn and Jennifer K. Colucci and Suzanne Mays and Emma H. D’Agostino and Alyssa M. Johnson and Nathan T. Jui and John Calvert and Eric A. Ortlund},
  year = {2026},
  journal = {Journal of Biological Chemistry},
  doi = {10.1016/j.jbc.2026.113731},
  url = {https://doi.org/10.1016/j.jbc.2026.113731}
}

RIS

TY  - JOUR
TI  - Structural basis of phospholipid sensing nuclear receptor LRH-1 recognition by carboxylic acid bioisosteres reveals an alternative ligand interaction site
AU  - Debipreeta Bhowmik
AU  - Michael L. Cato
AU  - Sarah M. Abraham
AU  - Racheal M. Spurlin
AU  - Autumn R. Flynn
AU  - Jennifer K. Colucci
AU  - Suzanne Mays
AU  - Emma H. D’Agostino
AU  - Alyssa M. Johnson
AU  - Nathan T. Jui
AU  - John Calvert
AU  - Eric A. Ortlund
PY  - 2026
JO  - Journal of Biological Chemistry
DO  - 10.1016/j.jbc.2026.113731
UR  - https://doi.org/10.1016/j.jbc.2026.113731
ER  - 

APA

Bhowmik, D., Cato, M. L., Abraham, S. M., Spurlin, R. M., Flynn, A. R., Colucci, J. K., Mays, S., D’Agostino, E. H., Johnson, A. M., Jui, N. T., Calvert, J., & Ortlund, E. A. (2026). Structural basis of phospholipid sensing nuclear receptor LRH-1 recognition by carboxylic acid bioisosteres reveals an alternative ligand interaction site. Journal of Biological Chemistry. https://doi.org/10.1016/j.jbc.2026.113731

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