Single-nucleus profiling reveals hepatocyte identity and immune features associated with corticosteroid response in severe alcohol-related hepatitis

Lukas Van Melkebeke, Markus Boesch, Tessa Ostyn, Wenxin Huang, Cansu Akkaya, Matthias van Sligtenhorst, Dania El Abyad, Fateme Safaeifard, Alexander Dumarey, Marie Wallays, Bram Boeckx, Rita Feio-Azevedo, Lena Smets, Thierry Gustot, Eric Trépo, Christophe Moreno, Antonella Putignano, Luc Lasser, Isabelle Colle, Pierre Deltenre, Astrid Marot, Baki Topal, Eveline Claus, Lawrence Bonne, Geert Maleux, Colinda Scheele, Tim Hendrikx, Frederik Nevens, Hannelie Korf, Tania Roskams, Alexandre Denadai-Souza, Diether Lambrechts, Olivier Govaere, Schalk Van der Merwe, Jef Verbeek

Open source

DOI: 10.1016/j.jhep.2026.04.002
Published: 2026-09
Container: Journal of Hepatology
Publisher: Elsevier BV
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1016/j.jhep.2026.04.002,
  title = {Single-nucleus profiling reveals hepatocyte identity and immune features associated with corticosteroid response in severe alcohol-related hepatitis},
  author = {Lukas Van Melkebeke and Markus Boesch and Tessa Ostyn and Wenxin Huang and Cansu Akkaya and Matthias van Sligtenhorst and Dania El Abyad and Fateme Safaeifard and Alexander Dumarey and Marie Wallays and Bram Boeckx and Rita Feio-Azevedo and Lena Smets and Thierry Gustot and Eric Trépo and Christophe Moreno and Antonella Putignano and Luc Lasser and Isabelle Colle and Pierre Deltenre and Astrid Marot and Baki Topal and Eveline Claus and Lawrence Bonne and Geert Maleux and Colinda Scheele and Tim Hendrikx and Frederik Nevens and Hannelie Korf and Tania Roskams and Alexandre Denadai-Souza and Diether Lambrechts and Olivier Govaere and Schalk Van der Merwe and Jef Verbeek},
  year = {2026},
  journal = {Journal of Hepatology},
  doi = {10.1016/j.jhep.2026.04.002},
  url = {https://doi.org/10.1016/j.jhep.2026.04.002}
}

RIS

TY  - JOUR
TI  - Single-nucleus profiling reveals hepatocyte identity and immune features associated with corticosteroid response in severe alcohol-related hepatitis
AU  - Lukas Van Melkebeke
AU  - Markus Boesch
AU  - Tessa Ostyn
AU  - Wenxin Huang
AU  - Cansu Akkaya
AU  - Matthias van Sligtenhorst
AU  - Dania El Abyad
AU  - Fateme Safaeifard
AU  - Alexander Dumarey
AU  - Marie Wallays
AU  - Bram Boeckx
AU  - Rita Feio-Azevedo
AU  - Lena Smets
AU  - Thierry Gustot
AU  - Eric Trépo
AU  - Christophe Moreno
AU  - Antonella Putignano
AU  - Luc Lasser
AU  - Isabelle Colle
AU  - Pierre Deltenre
AU  - Astrid Marot
AU  - Baki Topal
AU  - Eveline Claus
AU  - Lawrence Bonne
AU  - Geert Maleux
AU  - Colinda Scheele
AU  - Tim Hendrikx
AU  - Frederik Nevens
AU  - Hannelie Korf
AU  - Tania Roskams
AU  - Alexandre Denadai-Souza
AU  - Diether Lambrechts
AU  - Olivier Govaere
AU  - Schalk Van der Merwe
AU  - Jef Verbeek
PY  - 2026
JO  - Journal of Hepatology
DO  - 10.1016/j.jhep.2026.04.002
UR  - https://doi.org/10.1016/j.jhep.2026.04.002
ER  -

APA

Melkebeke, L. V., Boesch, M., Ostyn, T., Huang, W., Akkaya, C., Sligtenhorst, M. V., Abyad, D. E., Safaeifard, F., Dumarey, A., Wallays, M., Boeckx, B., Feio-Azevedo, R., Smets, L., Gustot, T., Trépo, E., Moreno, C., Putignano, A., Lasser, L., Colle, I., Deltenre, P., Marot, A., Topal, B., Claus, E., Bonne, L., Maleux, G., Scheele, C., Hendrikx, T., Nevens, F., Korf, H., Roskams, T., Denadai-Souza, A., Lambrechts, D., Govaere, O., Merwe, S. V. D., & Verbeek, J. (2026). Single-nucleus profiling reveals hepatocyte identity and immune features associated with corticosteroid response in severe alcohol-related hepatitis. Journal of Hepatology. https://doi.org/10.1016/j.jhep.2026.04.002

Source records

crossref · retrieved 2026-09-26T23:34:04.219Z