Single-cell and spatial transcriptomics characterisation of RSPO2+ nucleus pulposus cells reveals a WNT/FN1–CD44 degenerative axis and therapeutic targets in IVDD

Qiuwei Li, Guoyan Liang, Kaida Bo, Liang Kang, Peilin Jin, Chenhao Zhao, Renjie Zhang, Fengjuan Lyu, Cailiang Shen

Open source

DOI
10.1016/j.jot.2026.101203
Published
2026-09
Container
Journal of Orthopaedic Translation
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/j.jot.2026.101203,
  title = {Single-cell and spatial transcriptomics characterisation of RSPO2+ nucleus pulposus cells reveals a WNT/FN1–CD44 degenerative axis and therapeutic targets in IVDD},
  author = {Qiuwei Li and Guoyan Liang and Kaida Bo and Liang Kang and Peilin Jin and Chenhao Zhao and Renjie Zhang and Fengjuan Lyu and Cailiang Shen},
  year = {2026},
  journal = {Journal of Orthopaedic Translation},
  doi = {10.1016/j.jot.2026.101203},
  url = {https://doi.org/10.1016/j.jot.2026.101203}
}

RIS

TY  - JOUR
TI  - Single-cell and spatial transcriptomics characterisation of RSPO2+ nucleus pulposus cells reveals a WNT/FN1–CD44 degenerative axis and therapeutic targets in IVDD
AU  - Qiuwei Li
AU  - Guoyan Liang
AU  - Kaida Bo
AU  - Liang Kang
AU  - Peilin Jin
AU  - Chenhao Zhao
AU  - Renjie Zhang
AU  - Fengjuan Lyu
AU  - Cailiang Shen
PY  - 2026
JO  - Journal of Orthopaedic Translation
DO  - 10.1016/j.jot.2026.101203
UR  - https://doi.org/10.1016/j.jot.2026.101203
ER  - 

APA

Li, Q., Liang, G., Bo, K., Kang, L., Jin, P., Zhao, C., Zhang, R., Lyu, F., & Shen, C. (2026). Single-cell and spatial transcriptomics characterisation of RSPO2+ nucleus pulposus cells reveals a WNT/FN1–CD44 degenerative axis and therapeutic targets in IVDD. Journal of Orthopaedic Translation. https://doi.org/10.1016/j.jot.2026.101203

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