Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification
- DOI
- 10.1016/j.omtn.2018.06.010
- Published
- 2018-09
- Container
- Molecular Therapy Nucleic Acids
- Publisher
- Elsevier BV
- Open access
- unknown
Credibility signals
uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.
Show all credibility signals
- supportingDOI registered: A matching record was returned by Crossref.
- supportingDOI resolves: A matching record was returned by Crossref.
- not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility.
- not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made.
- not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made.
- not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made.
- not scoredROR affiliation: Not checked or no result supplied; no credibility inference made.
- not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredOpen access status: Not checked or no result supplied; no credibility inference made.
- not scoredPublication license: Not checked or no result supplied; no credibility inference made.
- not scoredPublication version: A publication version was supplied but is not scored.
- supportingMetadata completeness: All 6 scored descriptive metadata groups are present.
Cite this work
BibTeX
@article{allodium:10.1016/j.omtn.2018.06.010,
title = {Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification},
author = {Sriram Vaidyanathan and Krist T. Azizian and A.K.M. Ashiqul Haque and Jordana M. Henderson and Ayal Hendel and Sabrina Shore and Justin S. Antony and Richard I. Hogrefe and Michael S.D. Kormann and Matthew H. Porteus and Anton P. McCaffrey},
year = {2018},
journal = {Molecular Therapy Nucleic Acids},
doi = {10.1016/j.omtn.2018.06.010},
url = {https://doi.org/10.1016/j.omtn.2018.06.010}
}RIS
TY - JOUR TI - Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification AU - Sriram Vaidyanathan AU - Krist T. Azizian AU - A.K.M. Ashiqul Haque AU - Jordana M. Henderson AU - Ayal Hendel AU - Sabrina Shore AU - Justin S. Antony AU - Richard I. Hogrefe AU - Michael S.D. Kormann AU - Matthew H. Porteus AU - Anton P. McCaffrey PY - 2018 JO - Molecular Therapy Nucleic Acids DO - 10.1016/j.omtn.2018.06.010 UR - https://doi.org/10.1016/j.omtn.2018.06.010 ER -
APA
Vaidyanathan, S., Azizian, K. T., Haque, A. A., Henderson, J. M., Hendel, A., Shore, S., Antony, J. S., Hogrefe, R. I., Kormann, M. S., Porteus, M. H., & McCaffrey, A. P. (2018). Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification. Molecular Therapy Nucleic Acids. https://doi.org/10.1016/j.omtn.2018.06.010
Source records
- crossref · retrieved 2026-09-26T17:54:23.520Z