Are glutathionylated aldehyde reductases the missing piece of the "catecholaldehyde hypothesis" in Parkinson's disease? A medical hypothesis concerning the detoxification of 4-hydroxynonenal (HNE) and 3,4-dihydroxyphenylacetaldehyde (DOPAL).
- DOI
- 10.1016/j.redox.2026.104060
- Published
- 2026 Mar
- Container
- Redox biology
- Publisher
- Not recorded
- Open access
- yes
Credibility signals
limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.
Show all credibility signals
- cautionDOI registered: No matching Crossref record was present in this response.
- cautionDOI resolves: No matching Crossref record was present in this response.
- not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility.
- not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made.
- not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made.
- not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made.
- not scoredROR affiliation: Not checked or no result supplied; no credibility inference made.
- not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- supportingOpen access status: Normalized open-access status: open.
- not scoredPublication license: Not checked or no result supplied; no credibility inference made.
- not scoredPublication version: A publication version was supplied but is not scored.
- cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty.
Cite this work
BibTeX
@article{allodium:10.1016/j.redox.2026.104060,
title = {Are glutathionylated aldehyde reductases the missing piece of the "catecholaldehyde hypothesis" in Parkinson's disease? A medical hypothesis concerning the detoxification of 4-hydroxynonenal (HNE) and 3,4-dihydroxyphenylacetaldehyde (DOPAL).},
author = {Rotondo R and Russo M and Iacovelli F and Calabrese V and de Iure A and Gaglione M and Leonardi L and Cocorocchia G and Stocchi F and Stocchi V and de Pandis MF and Picconi B},
year = {2026},
journal = {Redox biology},
doi = {10.1016/j.redox.2026.104060},
url = {https://doi.org/10.1016/j.redox.2026.104060}
}RIS
TY - JOUR TI - Are glutathionylated aldehyde reductases the missing piece of the "catecholaldehyde hypothesis" in Parkinson's disease? A medical hypothesis concerning the detoxification of 4-hydroxynonenal (HNE) and 3,4-dihydroxyphenylacetaldehyde (DOPAL). AU - Rotondo R AU - Russo M AU - Iacovelli F AU - Calabrese V AU - de Iure A AU - Gaglione M AU - Leonardi L AU - Cocorocchia G AU - Stocchi F AU - Stocchi V AU - de Pandis MF AU - Picconi B PY - 2026 JO - Redox biology DO - 10.1016/j.redox.2026.104060 UR - https://doi.org/10.1016/j.redox.2026.104060 ER -
APA
R, R., M, R., F, I., V, C., A, D. I., M, G., L, L., G, C., F, S., V, S., MF, D. P., & B, P. (2026). Are glutathionylated aldehyde reductases the missing piece of the "catecholaldehyde hypothesis" in Parkinson's disease? A medical hypothesis concerning the detoxification of 4-hydroxynonenal (HNE) and 3,4-dihydroxyphenylacetaldehyde (DOPAL).. Redox biology. https://doi.org/10.1016/j.redox.2026.104060
Source records
- pubmed · retrieved 2026-09-25T07:29:25.237Z