Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data.

Saez-Atienzar S, Souza CDS, Chia R, Beal SN, Lorenzini I, Huang R, Levy J, Burciu C, Ding J, Gibbs JR, Jones A, Dewan R, Pensato V, Peverelli S, Corrado L, van Vugt JJFA, van Rheenen W, Tunca C, Bayraktar E, Xia M, International ALS Genomics Consortium, ITALSGEN Consortium, SLAGEN Consortium, Project MinE ALS Sequencing Consortium, Iacoangeli A, Shatunov A, Tiloca C, Ticozzi N, Verde F, Mazzini L, Kenna K, Al Khleifat A, Opie-Martin S, Raggi F, Filosto M, Piccinelli SC, Padovani A, Gagliardi S, Inghilleri M, Ferlini A, Vasta R, Calvo A, Moglia C, Canosa A, Manera U, Grassano M, Mandrioli J, Mora G, Lunetta C, Tanel R, Trojsi F, Cardinali P, Gallone S, Brunetti M, Galimberti D, Serpente M, Fenoglio C, Scarpini E, Comi GP, Corti S, Del Bo R, Ceroni M, Pinter GL, Taroni F, Bella ED, Bersano E, Curtis CJ, Lee SH, Chung R, Patel H, Morrison KE, Cooper-Knock J, Shaw PJ, Breen G, Dobson RJB, Dalgard CL, American Genome Center, Scholz SW, Al-Chalabi A, van den Berg LH, McLaughlin R, Hardiman O, Cereda C, Sorarù G, D'Alfonso S, Chandran S, Pal S, Ratti A, Gellera C, Johnson K, Doucet-O'Hare T, Pasternack N, Wang T, Nath A, Siciliano G, Silani V, Başak AN, Veldink JH, Camu W, Glass JD, Landers JE, Chiò A, Sattler R, Shaw CE, Ferraiuolo L, Fogh I, Traynor BJ

Open source

DOI: 10.1016/j.xgen.2024.100679
Published: 2024 Nov 13
Container: Cell genomics
Publisher: Not recorded
Open access: yes

Credibility signals

uncertain Score 53/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
supportingDirectory of Open Access Journals: A matching record was returned by DOAJ. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1016/j.xgen.2024.100679,
  title = {Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data.},
  author = {Saez-Atienzar S and Souza CDS and Chia R and Beal SN and Lorenzini I and Huang R and Levy J and Burciu C and Ding J and Gibbs JR and Jones A and Dewan R and Pensato V and Peverelli S and Corrado L and van Vugt JJFA and van Rheenen W and Tunca C and Bayraktar E and Xia M and International ALS Genomics Consortium and ITALSGEN Consortium and SLAGEN Consortium and Project MinE ALS Sequencing Consortium and Iacoangeli A and Shatunov A and Tiloca C and Ticozzi N and Verde F and Mazzini L and Kenna K and Al Khleifat A and Opie-Martin S and Raggi F and Filosto M and Piccinelli SC and Padovani A and Gagliardi S and Inghilleri M and Ferlini A and Vasta R and Calvo A and Moglia C and Canosa A and Manera U and Grassano M and Mandrioli J and Mora G and Lunetta C and Tanel R and Trojsi F and Cardinali P and Gallone S and Brunetti M and Galimberti D and Serpente M and Fenoglio C and Scarpini E and Comi GP and Corti S and Del Bo R and Ceroni M and Pinter GL and Taroni F and Bella ED and Bersano E and Curtis CJ and Lee SH and Chung R and Patel H and Morrison KE and Cooper-Knock J and Shaw PJ and Breen G and Dobson RJB and Dalgard CL and American Genome Center and Scholz SW and Al-Chalabi A and van den Berg LH and McLaughlin R and Hardiman O and Cereda C and Sorarù G and D'Alfonso S and Chandran S and Pal S and Ratti A and Gellera C and Johnson K and Doucet-O'Hare T and Pasternack N and Wang T and Nath A and Siciliano G and Silani V and Başak AN and Veldink JH and Camu W and Glass JD and Landers JE and Chiò A and Sattler R and Shaw CE and Ferraiuolo L and Fogh I and Traynor BJ},
  year = {2024},
  journal = {Cell genomics},
  doi = {10.1016/j.xgen.2024.100679},
  url = {https://doi.org/10.1016/j.xgen.2024.100679}
}

RIS

TY  - JOUR
TI  - Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data.
AU  - Saez-Atienzar S
AU  - Souza CDS
AU  - Chia R
AU  - Beal SN
AU  - Lorenzini I
AU  - Huang R
AU  - Levy J
AU  - Burciu C
AU  - Ding J
AU  - Gibbs JR
AU  - Jones A
AU  - Dewan R
AU  - Pensato V
AU  - Peverelli S
AU  - Corrado L
AU  - van Vugt JJFA
AU  - van Rheenen W
AU  - Tunca C
AU  - Bayraktar E
AU  - Xia M
AU  - International ALS Genomics Consortium
AU  - ITALSGEN Consortium
AU  - SLAGEN Consortium
AU  - Project MinE ALS Sequencing Consortium
AU  - Iacoangeli A
AU  - Shatunov A
AU  - Tiloca C
AU  - Ticozzi N
AU  - Verde F
AU  - Mazzini L
AU  - Kenna K
AU  - Al Khleifat A
AU  - Opie-Martin S
AU  - Raggi F
AU  - Filosto M
AU  - Piccinelli SC
AU  - Padovani A
AU  - Gagliardi S
AU  - Inghilleri M
AU  - Ferlini A
AU  - Vasta R
AU  - Calvo A
AU  - Moglia C
AU  - Canosa A
AU  - Manera U
AU  - Grassano M
AU  - Mandrioli J
AU  - Mora G
AU  - Lunetta C
AU  - Tanel R
AU  - Trojsi F
AU  - Cardinali P
AU  - Gallone S
AU  - Brunetti M
AU  - Galimberti D
AU  - Serpente M
AU  - Fenoglio C
AU  - Scarpini E
AU  - Comi GP
AU  - Corti S
AU  - Del Bo R
AU  - Ceroni M
AU  - Pinter GL
AU  - Taroni F
AU  - Bella ED
AU  - Bersano E
AU  - Curtis CJ
AU  - Lee SH
AU  - Chung R
AU  - Patel H
AU  - Morrison KE
AU  - Cooper-Knock J
AU  - Shaw PJ
AU  - Breen G
AU  - Dobson RJB
AU  - Dalgard CL
AU  - American Genome Center
AU  - Scholz SW
AU  - Al-Chalabi A
AU  - van den Berg LH
AU  - McLaughlin R
AU  - Hardiman O
AU  - Cereda C
AU  - Sorarù G
AU  - D'Alfonso S
AU  - Chandran S
AU  - Pal S
AU  - Ratti A
AU  - Gellera C
AU  - Johnson K
AU  - Doucet-O'Hare T
AU  - Pasternack N
AU  - Wang T
AU  - Nath A
AU  - Siciliano G
AU  - Silani V
AU  - Başak AN
AU  - Veldink JH
AU  - Camu W
AU  - Glass JD
AU  - Landers JE
AU  - Chiò A
AU  - Sattler R
AU  - Shaw CE
AU  - Ferraiuolo L
AU  - Fogh I
AU  - Traynor BJ
PY  - 2024
JO  - Cell genomics
DO  - 10.1016/j.xgen.2024.100679
UR  - https://doi.org/10.1016/j.xgen.2024.100679
ER  -

APA

S, S., CDS, S., R, C., SN, B., I, L., R, H., J, L., C, B., J, D., JR, G., A, J., R, D., V, P., S, P., L, C., JJFA, V. V., W, V. R., C, T., E, B., M, X., Consortium, I. A. G., Consortium, I., Consortium, S., Consortium, P. M. A. S., A, I., A, S., C, T., N, T., F, V., L, M., K, K., A, A. K., S, O., F, R., M, F., SC, P., A, P., S, G., M, I., A, F., R, V., A, C., C, M., A, C., U, M., M, G., J, M., G, M., C, L., R, T., F, T., P, C., S, G., M, B., D, G., M, S., C, F., E, S., GP, C., S, C., R, D. B., M, C., GL, P., F, T., ED, B., E, B., CJ, C., SH, L., R, C., H, P., KE, M., J, C., PJ, S., G, B., RJB, D., CL, D., Center, A. G., SW, S., A, A., LH, V. D. B., R, M., O, H., C, C., G, S., S, D., S, C., S, P., A, R., C, G., K, J., T, D., N, P., T, W., A, N., G, S., V, S., AN, B., JH, V., W, C., JD, G., JE, L., A, C., R, S., CE, S., L, F., I, F., & BJ, T. (2024). Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data.. Cell genomics. https://doi.org/10.1016/j.xgen.2024.100679

Source records

pubmed · retrieved 2026-09-25T12:28:57.608Z
europe-pmc · retrieved 2026-09-25T12:28:57.618Z
doaj · retrieved 2026-09-25T12:28:57.620Z
hal · retrieved 2026-09-25T12:28:57.658Z