Optimized chemical structure extends silencing duration of therapeutic siRNAs in dividing cancer and immune cells

Anastasia Kremer, Tatyana Ryaykenen, Xavier Segarra-Visent, Melanie Sauer, Leon Breuer, Yiying Wu, Qi Tang, David A. Cooper, Dimas Echeverria, Clothilde Philouze, Emilie Bayon, Dan Georgess, Reka A. Haraszti

Open source

DOI
10.1016/j.ymthe.2025.08.017
Published
2025-11
Container
Molecular Therapy
Publisher
Elsevier BV
Open access
unknown

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Cite this work

BibTeX

@article{allodium:10.1016/j.ymthe.2025.08.017,
  title = {Optimized chemical structure extends silencing duration of therapeutic siRNAs in dividing cancer and immune cells},
  author = {Anastasia Kremer and Tatyana Ryaykenen and Xavier Segarra-Visent and Melanie Sauer and Leon Breuer and Yiying Wu and Qi Tang and David A. Cooper and Dimas Echeverria and Clothilde Philouze and Emilie Bayon and Dan Georgess and Reka A. Haraszti},
  year = {2025},
  journal = {Molecular Therapy},
  doi = {10.1016/j.ymthe.2025.08.017},
  url = {https://doi.org/10.1016/j.ymthe.2025.08.017}
}

RIS

TY  - JOUR
TI  - Optimized chemical structure extends silencing duration of therapeutic siRNAs in dividing cancer and immune cells
AU  - Anastasia Kremer
AU  - Tatyana Ryaykenen
AU  - Xavier Segarra-Visent
AU  - Melanie Sauer
AU  - Leon Breuer
AU  - Yiying Wu
AU  - Qi Tang
AU  - David A. Cooper
AU  - Dimas Echeverria
AU  - Clothilde Philouze
AU  - Emilie Bayon
AU  - Dan Georgess
AU  - Reka A. Haraszti
PY  - 2025
JO  - Molecular Therapy
DO  - 10.1016/j.ymthe.2025.08.017
UR  - https://doi.org/10.1016/j.ymthe.2025.08.017
ER  - 

APA

Kremer, A., Ryaykenen, T., Segarra-Visent, X., Sauer, M., Breuer, L., Wu, Y., Tang, Q., Cooper, D. A., Echeverria, D., Philouze, C., Bayon, E., Georgess, D., & Haraszti, R. A. (2025). Optimized chemical structure extends silencing duration of therapeutic siRNAs in dividing cancer and immune cells. Molecular Therapy. https://doi.org/10.1016/j.ymthe.2025.08.017

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