Synthesis and pharmacological activity of a novel water-soluble hepatocyte-specific polymeric prodrug of prostaglandin E 1 using lactosylated poly( l -glutamic hydrazide) as a carrier 1 1Abbreviations: PGE1, prostaglandin E1; PLGA-HZ, poly(l-glutamic hydrazide); Lac-NH-PLGA, lactosylated poly(l-glutamic hydrazide); PGE1 conjugate, prostaglandin E1 prodrug using Lac-NH-PLGA as a carrier; DTPA anhydride, diethylenetriamine-N,N,N′,N″,N″-pentaacetic dianhydride; GPT, glutamic pyruvic transaminase; AUC, area under the plasma concentration-time curve; ROS, reactive oxygen species; and EP receptor, receptor for prostaglandins expressed on a plasma membrane.
- DOI
- 10.1016/s0006-2952(01)00799-7
- Published
- 2001-12
- Container
- Biochemical Pharmacology
- Publisher
- Elsevier BV
- Open access
- unknown
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BibTeX
@article{allodium:10.1016/s0006-2952-01-00799-7,
title = {Synthesis and pharmacological activity of a novel water-soluble hepatocyte-specific polymeric prodrug of prostaglandin E 1 using lactosylated poly( l -glutamic hydrazide) as a carrier 1 1Abbreviations: PGE1, prostaglandin E1; PLGA-HZ, poly(l-glutamic hydrazide); Lac-NH-PLGA, lactosylated poly(l-glutamic hydrazide); PGE1 conjugate, prostaglandin E1 prodrug using Lac-NH-PLGA as a carrier; DTPA anhydride, diethylenetriamine-N,N,N′,N″,N″-pentaacetic dianhydride; GPT, glutamic pyruvic transaminase; AUC, area under the plasma concentration-time curve; ROS, reactive oxygen species; and EP receptor, receptor for prostaglandins expressed on a plasma membrane.},
author = {Ken Akamatsu and Yasuomi Yamasaki and Makiya Nishikawa and Yoshinobu Takakura and Mitsuru Hashida},
year = {2001},
journal = {Biochemical Pharmacology},
doi = {10.1016/s0006-2952(01)00799-7},
url = {https://doi.org/10.1016/s0006-2952(01)00799-7}
}RIS
TY - JOUR TI - Synthesis and pharmacological activity of a novel water-soluble hepatocyte-specific polymeric prodrug of prostaglandin E 1 using lactosylated poly( l -glutamic hydrazide) as a carrier 1 1Abbreviations: PGE1, prostaglandin E1; PLGA-HZ, poly(l-glutamic hydrazide); Lac-NH-PLGA, lactosylated poly(l-glutamic hydrazide); PGE1 conjugate, prostaglandin E1 prodrug using Lac-NH-PLGA as a carrier; DTPA anhydride, diethylenetriamine-N,N,N′,N″,N″-pentaacetic dianhydride; GPT, glutamic pyruvic transaminase; AUC, area under the plasma concentration-time curve; ROS, reactive oxygen species; and EP receptor, receptor for prostaglandins expressed on a plasma membrane. AU - Ken Akamatsu AU - Yasuomi Yamasaki AU - Makiya Nishikawa AU - Yoshinobu Takakura AU - Mitsuru Hashida PY - 2001 JO - Biochemical Pharmacology DO - 10.1016/s0006-2952(01)00799-7 UR - https://doi.org/10.1016/s0006-2952(01)00799-7 ER -
APA
Akamatsu, K., Yamasaki, Y., Nishikawa, M., Takakura, Y., & Hashida, M. (2001). Synthesis and pharmacological activity of a novel water-soluble hepatocyte-specific polymeric prodrug of prostaglandin E 1 using lactosylated poly( l -glutamic hydrazide) as a carrier 1 1Abbreviations: PGE1, prostaglandin E1; PLGA-HZ, poly(l-glutamic hydrazide); Lac-NH-PLGA, lactosylated poly(l-glutamic hydrazide); PGE1 conjugate, prostaglandin E1 prodrug using Lac-NH-PLGA as a carrier; DTPA anhydride, diethylenetriamine-N,N,N′,N″,N″-pentaacetic dianhydride; GPT, glutamic pyruvic transaminase; AUC, area under the plasma concentration-time curve; ROS, reactive oxygen species; and EP receptor, receptor for prostaglandins expressed on a plasma membrane.. Biochemical Pharmacology. https://doi.org/10.1016/s0006-2952(01)00799-7
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