Anthracycline-containing and taxane-containing chemotherapy for early-stage operable breast cancer: a patient-level meta-analysis of 100 000 women from 86 randomised trials

Jeremy Braybrooke, Rosie Bradley, Richard Gray, Robert K Hills, Hongchao Pan, Richard Peto, David Dodwell, Paul McGale, Carolyn Taylor, Tomohiko Aihara, Stewart Anderson, Joanne Blum, Fatima Cardoso, Xiaosong Chen, John P Crown, Bent Ejlertsen, Thomas W P Friedl, Nadia Harbeck, Wolfgang Janni, Maj-Britt Jensen, Eleftherios Mamounas, Kazutaka Narui, Ulrike Nitz, Larry Norton, Joyce O'Shaughnessy, Martine Piccart, Nicholas Robert, Zhi-Ming Shao, Dennis Slamon, Joseph Sparano, Toru Watanabe, Greg Yothers, Ke-Da Yu, Richard Berry, Clare Boddington, Mike Clarke, Christina Davies, Lucy Davies, Fran Duane, Vaughan Evans, Jo Gay, Lucy Gettins, Jon Godwin, Sam James, Hui Lui, Zulian Lui, Elizabeth MacKinnon, Gurdeep Mannu, Theresa McHugh, Philip Morris, Simon Read, Ewan Straiton, Aman Buzdar, Vera J Suman, Kelly K Hunt, Robert C F Leonard, Janine Mansi, Catherine Delbaldo, Pascal Piedbois, Emmanuel Quinaux, Christian Fesl, Michael Gnant, Lidija Sölkner, Guenther Steger, Hans Petter Eikesdal, Per Eystein Lønning, Valerie Bee, Helena Fung, John Mackey, Miguel Martin, Michael Press, Evandro De Azambuja, Richard Gelber, Meredith Regan, Angelo Di Leo, Veerle Van Dooren, Jean Marie Nogaret, John Bartlett, Bingshu E Chen, Karen Gelmon, Paul E Goss, Mark N Levine, Wendy Parulekar, Kathleen I Pritchard, Lois Shepherd, Donald Berry, Constance Cirrincione, Lawrence N Shulman, Eric Winer, Rebecca S Gelman, Jay R Harris, Craig Henderson, Charles L Shapiro, Peer Christiansen, Marianne Ewertz, Henning T Mouridsen, Elise Van Leeuwen, Sabine Linn, Annelot G J Van Rossum, Harm Van Tinteren, Erik Van Werkhoven, Lori Goldstein, Robert Gray, Wolfgang Eiermann, Luca Gianni, Pinuccia Valagussa, Jan Bogaerts, Herve Bonnefoi, Coralie Poncet, Riikka Huovinen, Heikki Joensuu, Jacques Bonneterre, Pierre Fargeot, Pierre Fumoleau, Pierre Kerbrat, Elisabeth Luporsi, Moïse Namer, Eva M Carrasco, Miguel Angel Segui, Christoph Meisner, Sibylle Loibl, Valentina Nekljudova, Christoph Thomssen, Gunter Von Minckwitz, Sherko Kümmel, Massimo Lopez, Patrizia Vici, George Fountzilas, Georgia Koliou, Dimitrios Mavroudis, Emmanouil Saloustros, Etienne Brain, Suzette Delaloge, Stefan Michiels, Simone Mathoulin-Pelissier, Jose Bines, Roberta M B Sarmento, Gianni Bonadonna, Cristina Brambilla, Anna Rossi, Judith Bliss, Raoul Charles Coombes, Lucy Kilburn, Michel Marty, Dino Amadori, Francesco Boccardo, Oriana Nanni, Alessandra Rubagotti, Emanuela Scarpi, Norikazu Masuda, Masakazu Toi, Takayuki Ueno, Takashi Ishikawa, Koji Matsumoto, Shintaro Takao, Harald Sommer, Pericles Foroglou, George Giokas, D Kondylis, Byron Lissaios, Mattea Reinisch, Keun Seok Lee, Byung-Ho Nam, Jung Sil Ro, Andrea De Matteis, Francesco Perrone, Gong Tang, Norman Wolmark, Yasuo Hozumi, Yasuo Nomura, Helena Earl, Louise Hiller, Anne-Laure Vallier, Lucia De Mastro, Macro Venturini, Thierry Delozier, Jerome Lemonnier, Anne-Laure Martin, Henri Roché, Marc Spielmann, Xiasong Chen, Kunwei Shen, Kathy Albain, William Barlow, George T Budd, Julie Gralow, Dan Hayes, Peter Bartlett-Lee, Paul Ellis, Angelo Raffaele Bianco, Michelino De Laurentiis, Sabino De Placido, Hans Wildiers, Limin Hsu, Oleg Eremin, Leslie G Walker, Johan Ahlgren, Carl Blomqvist, Lars Holmberg, Henrik Lindman, Lina Asmar, Stephen E Jones, Oleg Gluz, Cornelia Liedtke, Rodrigo Arriagada, Elizabeth Bergsten-Nordström, Lisa Carey, Robert Coleman, Jack Cuzick, Nancy Davidson, James Dignam, Mitch Dowsett, Prudence A Francis, Matthew P Goetz, Pam Goodwin, Pat Halpin-Murphy, Catherine Hill, Reshma Jagsi, Hirofumi Mukai, Yasuo Ohashi, Lori Pierce, Philip Poortmans, Vinod Raina, Daniel Rea, John Robertson, Emiel Rutgers, Roberto Salgado, Tanja Spanic, Andrew Tutt, Giuseppe Viale, Xiang Wang, Tim Whelan, Nicholas Wilcken, David Cameron, Jonas Bergh, Sandra M Swain

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DOI
10.1016/s0140-6736(23)00285-4
Published
2023-04
Container
The Lancet
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/s0140-6736-23-00285-4,
  title = {Anthracycline-containing and taxane-containing chemotherapy for early-stage operable breast cancer: a patient-level meta-analysis of 100 000 women from 86 randomised trials},
  author = {Jeremy Braybrooke and Rosie Bradley and Richard Gray and Robert K Hills and Hongchao Pan and Richard Peto and David Dodwell and Paul McGale and Carolyn Taylor and Tomohiko Aihara and Stewart Anderson and Joanne Blum and Fatima Cardoso and Xiaosong Chen and John P Crown and Bent Ejlertsen and Thomas W P Friedl and Nadia Harbeck and Wolfgang Janni and Maj-Britt Jensen and Eleftherios Mamounas and Kazutaka Narui and Ulrike Nitz and Larry Norton and Joyce O'Shaughnessy and Martine Piccart and Nicholas Robert and Zhi-Ming Shao and Dennis Slamon and Joseph Sparano and Toru Watanabe and Greg Yothers and Ke-Da Yu and Richard Berry and Clare Boddington and Mike Clarke and Christina Davies and Lucy Davies and Fran Duane and Vaughan Evans and Jo Gay and Lucy Gettins and Jon Godwin and Sam James and Hui Lui and Zulian Lui and Elizabeth MacKinnon and Gurdeep Mannu and Theresa McHugh and Philip Morris and Simon Read and Ewan Straiton and Aman Buzdar and Vera J Suman and Kelly K Hunt and Robert C F Leonard and Janine Mansi and Catherine Delbaldo and Pascal Piedbois and Emmanuel Quinaux and Christian Fesl and Michael Gnant and Lidija Sölkner and Guenther Steger and Hans Petter Eikesdal and Per Eystein Lønning and Valerie Bee and Helena Fung and John Mackey and Miguel Martin and Michael Press and Evandro De Azambuja and Richard Gelber and Meredith Regan and Angelo Di Leo and Veerle Van Dooren and Jean Marie Nogaret and John Bartlett and Bingshu E Chen and Karen Gelmon and Paul E Goss and Mark N Levine and Wendy Parulekar and Kathleen I Pritchard and Lois Shepherd and Donald Berry and Constance Cirrincione and Lawrence N Shulman and Eric Winer and Rebecca S Gelman and Jay R Harris and Craig Henderson and Charles L Shapiro and Peer Christiansen and Marianne Ewertz and Henning T Mouridsen and Elise Van Leeuwen and Sabine Linn and Annelot G J Van Rossum and Harm Van Tinteren and Erik Van Werkhoven and Lori Goldstein and Robert Gray and Wolfgang Eiermann and Luca Gianni and Pinuccia Valagussa and Jan Bogaerts and Herve Bonnefoi and Coralie Poncet and Riikka Huovinen and Heikki Joensuu and Jacques Bonneterre and Pierre Fargeot and Pierre Fumoleau and Pierre Kerbrat and Elisabeth Luporsi and Moïse Namer and Eva M Carrasco and Miguel Angel Segui and Christoph Meisner and Sibylle Loibl and Valentina Nekljudova and Christoph Thomssen and Gunter Von Minckwitz and Sherko Kümmel and Massimo Lopez and Patrizia Vici and George Fountzilas and Georgia Koliou and Dimitrios Mavroudis and Emmanouil Saloustros and Etienne Brain and Suzette Delaloge and Stefan Michiels and Simone Mathoulin-Pelissier and Jose Bines and Roberta M B Sarmento and Gianni Bonadonna and Cristina Brambilla and Anna Rossi and Judith Bliss and Raoul Charles Coombes and Lucy Kilburn and Michel Marty and Dino Amadori and Francesco Boccardo and Oriana Nanni and Alessandra Rubagotti and Emanuela Scarpi and Norikazu Masuda and Masakazu Toi and Takayuki Ueno and Takashi Ishikawa and Koji Matsumoto and Shintaro Takao and Harald Sommer and Pericles Foroglou and George Giokas and D Kondylis and Byron Lissaios and Mattea Reinisch and Keun Seok Lee and Byung-Ho Nam and Jung Sil Ro and Andrea De Matteis and Francesco Perrone and Gong Tang and Norman Wolmark and Yasuo Hozumi and Yasuo Nomura and Helena Earl and Louise Hiller and Anne-Laure Vallier and Lucia De Mastro and Macro Venturini and Thierry Delozier and Jerome Lemonnier and Anne-Laure Martin and Henri Roché and Marc Spielmann and Xiasong Chen and Kunwei Shen and Kathy Albain and William Barlow and George T Budd and Julie Gralow and Dan Hayes and Peter Bartlett-Lee and Paul Ellis and Angelo Raffaele Bianco and Michelino De Laurentiis and Sabino De Placido and Hans Wildiers and Limin Hsu and Oleg Eremin and Leslie G Walker and Johan Ahlgren and Carl Blomqvist and Lars Holmberg and Henrik Lindman and Lina Asmar and Stephen E Jones and Oleg Gluz and Cornelia Liedtke and Rodrigo Arriagada and Elizabeth Bergsten-Nordström and Lisa Carey and Robert Coleman and Jack Cuzick and Nancy Davidson and James Dignam and Mitch Dowsett and Prudence A Francis and Matthew P Goetz and Pam Goodwin and Pat Halpin-Murphy and Catherine Hill and Reshma Jagsi and Hirofumi Mukai and Yasuo Ohashi and Lori Pierce and Philip Poortmans and Vinod Raina and Daniel Rea and John Robertson and Emiel Rutgers and Roberto Salgado and Tanja Spanic and Andrew Tutt and Giuseppe Viale and Xiang Wang and Tim Whelan and Nicholas Wilcken and David Cameron and Jonas Bergh and Sandra M Swain},
  year = {2023},
  journal = {The Lancet},
  doi = {10.1016/s0140-6736(23)00285-4},
  url = {https://doi.org/10.1016/s0140-6736(23)00285-4}
}

RIS

TY  - JOUR
TI  - Anthracycline-containing and taxane-containing chemotherapy for early-stage operable breast cancer: a patient-level meta-analysis of 100 000 women from 86 randomised trials
AU  - Jeremy Braybrooke
AU  - Rosie Bradley
AU  - Richard Gray
AU  - Robert K Hills
AU  - Hongchao Pan
AU  - Richard Peto
AU  - David Dodwell
AU  - Paul McGale
AU  - Carolyn Taylor
AU  - Tomohiko Aihara
AU  - Stewart Anderson
AU  - Joanne Blum
AU  - Fatima Cardoso
AU  - Xiaosong Chen
AU  - John P Crown
AU  - Bent Ejlertsen
AU  - Thomas W P Friedl
AU  - Nadia Harbeck
AU  - Wolfgang Janni
AU  - Maj-Britt Jensen
AU  - Eleftherios Mamounas
AU  - Kazutaka Narui
AU  - Ulrike Nitz
AU  - Larry Norton
AU  - Joyce O'Shaughnessy
AU  - Martine Piccart
AU  - Nicholas Robert
AU  - Zhi-Ming Shao
AU  - Dennis Slamon
AU  - Joseph Sparano
AU  - Toru Watanabe
AU  - Greg Yothers
AU  - Ke-Da Yu
AU  - Richard Berry
AU  - Clare Boddington
AU  - Mike Clarke
AU  - Christina Davies
AU  - Lucy Davies
AU  - Fran Duane
AU  - Vaughan Evans
AU  - Jo Gay
AU  - Lucy Gettins
AU  - Jon Godwin
AU  - Sam James
AU  - Hui Lui
AU  - Zulian Lui
AU  - Elizabeth MacKinnon
AU  - Gurdeep Mannu
AU  - Theresa McHugh
AU  - Philip Morris
AU  - Simon Read
AU  - Ewan Straiton
AU  - Aman Buzdar
AU  - Vera J Suman
AU  - Kelly K Hunt
AU  - Robert C F Leonard
AU  - Janine Mansi
AU  - Catherine Delbaldo
AU  - Pascal Piedbois
AU  - Emmanuel Quinaux
AU  - Christian Fesl
AU  - Michael Gnant
AU  - Lidija Sölkner
AU  - Guenther Steger
AU  - Hans Petter Eikesdal
AU  - Per Eystein Lønning
AU  - Valerie Bee
AU  - Helena Fung
AU  - John Mackey
AU  - Miguel Martin
AU  - Michael Press
AU  - Evandro De Azambuja
AU  - Richard Gelber
AU  - Meredith Regan
AU  - Angelo Di Leo
AU  - Veerle Van Dooren
AU  - Jean Marie Nogaret
AU  - John Bartlett
AU  - Bingshu E Chen
AU  - Karen Gelmon
AU  - Paul E Goss
AU  - Mark N Levine
AU  - Wendy Parulekar
AU  - Kathleen I Pritchard
AU  - Lois Shepherd
AU  - Donald Berry
AU  - Constance Cirrincione
AU  - Lawrence N Shulman
AU  - Eric Winer
AU  - Rebecca S Gelman
AU  - Jay R Harris
AU  - Craig Henderson
AU  - Charles L Shapiro
AU  - Peer Christiansen
AU  - Marianne Ewertz
AU  - Henning T Mouridsen
AU  - Elise Van Leeuwen
AU  - Sabine Linn
AU  - Annelot G J Van Rossum
AU  - Harm Van Tinteren
AU  - Erik Van Werkhoven
AU  - Lori Goldstein
AU  - Robert Gray
AU  - Wolfgang Eiermann
AU  - Luca Gianni
AU  - Pinuccia Valagussa
AU  - Jan Bogaerts
AU  - Herve Bonnefoi
AU  - Coralie Poncet
AU  - Riikka Huovinen
AU  - Heikki Joensuu
AU  - Jacques Bonneterre
AU  - Pierre Fargeot
AU  - Pierre Fumoleau
AU  - Pierre Kerbrat
AU  - Elisabeth Luporsi
AU  - Moïse Namer
AU  - Eva M Carrasco
AU  - Miguel Angel Segui
AU  - Christoph Meisner
AU  - Sibylle Loibl
AU  - Valentina Nekljudova
AU  - Christoph Thomssen
AU  - Gunter Von Minckwitz
AU  - Sherko Kümmel
AU  - Massimo Lopez
AU  - Patrizia Vici
AU  - George Fountzilas
AU  - Georgia Koliou
AU  - Dimitrios Mavroudis
AU  - Emmanouil Saloustros
AU  - Etienne Brain
AU  - Suzette Delaloge
AU  - Stefan Michiels
AU  - Simone Mathoulin-Pelissier
AU  - Jose Bines
AU  - Roberta M B Sarmento
AU  - Gianni Bonadonna
AU  - Cristina Brambilla
AU  - Anna Rossi
AU  - Judith Bliss
AU  - Raoul Charles Coombes
AU  - Lucy Kilburn
AU  - Michel Marty
AU  - Dino Amadori
AU  - Francesco Boccardo
AU  - Oriana Nanni
AU  - Alessandra Rubagotti
AU  - Emanuela Scarpi
AU  - Norikazu Masuda
AU  - Masakazu Toi
AU  - Takayuki Ueno
AU  - Takashi Ishikawa
AU  - Koji Matsumoto
AU  - Shintaro Takao
AU  - Harald Sommer
AU  - Pericles Foroglou
AU  - George Giokas
AU  - D Kondylis
AU  - Byron Lissaios
AU  - Mattea Reinisch
AU  - Keun Seok Lee
AU  - Byung-Ho Nam
AU  - Jung Sil Ro
AU  - Andrea De Matteis
AU  - Francesco Perrone
AU  - Gong Tang
AU  - Norman Wolmark
AU  - Yasuo Hozumi
AU  - Yasuo Nomura
AU  - Helena Earl
AU  - Louise Hiller
AU  - Anne-Laure Vallier
AU  - Lucia De Mastro
AU  - Macro Venturini
AU  - Thierry Delozier
AU  - Jerome Lemonnier
AU  - Anne-Laure Martin
AU  - Henri Roché
AU  - Marc Spielmann
AU  - Xiasong Chen
AU  - Kunwei Shen
AU  - Kathy Albain
AU  - William Barlow
AU  - George T Budd
AU  - Julie Gralow
AU  - Dan Hayes
AU  - Peter Bartlett-Lee
AU  - Paul Ellis
AU  - Angelo Raffaele Bianco
AU  - Michelino De Laurentiis
AU  - Sabino De Placido
AU  - Hans Wildiers
AU  - Limin Hsu
AU  - Oleg Eremin
AU  - Leslie G Walker
AU  - Johan Ahlgren
AU  - Carl Blomqvist
AU  - Lars Holmberg
AU  - Henrik Lindman
AU  - Lina Asmar
AU  - Stephen E Jones
AU  - Oleg Gluz
AU  - Cornelia Liedtke
AU  - Rodrigo Arriagada
AU  - Elizabeth Bergsten-Nordström
AU  - Lisa Carey
AU  - Robert Coleman
AU  - Jack Cuzick
AU  - Nancy Davidson
AU  - James Dignam
AU  - Mitch Dowsett
AU  - Prudence A Francis
AU  - Matthew P Goetz
AU  - Pam Goodwin
AU  - Pat Halpin-Murphy
AU  - Catherine Hill
AU  - Reshma Jagsi
AU  - Hirofumi Mukai
AU  - Yasuo Ohashi
AU  - Lori Pierce
AU  - Philip Poortmans
AU  - Vinod Raina
AU  - Daniel Rea
AU  - John Robertson
AU  - Emiel Rutgers
AU  - Roberto Salgado
AU  - Tanja Spanic
AU  - Andrew Tutt
AU  - Giuseppe Viale
AU  - Xiang Wang
AU  - Tim Whelan
AU  - Nicholas Wilcken
AU  - David Cameron
AU  - Jonas Bergh
AU  - Sandra M Swain
PY  - 2023
JO  - The Lancet
DO  - 10.1016/s0140-6736(23)00285-4
UR  - https://doi.org/10.1016/s0140-6736(23)00285-4
ER  -

APA

Braybrooke, J., Bradley, R., Gray, R., Hills, R. K., Pan, H., Peto, R., Dodwell, D., McGale, P., Taylor, C., Aihara, T., Anderson, S., Blum, J., Cardoso, F., Chen, X., Crown, J. P., Ejlertsen, B., Friedl, T. W. P., Harbeck, N., Janni, W., Jensen, M., Mamounas, E., Narui, K., Nitz, U., Norton, L., O'Shaughnessy, J., Piccart, M., Robert, N., Shao, Z., Slamon, D., Sparano, J., Watanabe, T., Yothers, G., Yu, K., Berry, R., Boddington, C., Clarke, M., Davies, C., Davies, L., Duane, F., Evans, V., Gay, J., Gettins, L., Godwin, J., James, S., Lui, H., Lui, Z., MacKinnon, E., Mannu, G., McHugh, T., Morris, P., Read, S., Straiton, E., Buzdar, A., Suman, V. J., Hunt, K. K., Leonard, R. C. F., Mansi, J., Delbaldo, C., Piedbois, P., Quinaux, E., Fesl, C., Gnant, M., Sölkner, L., Steger, G., Eikesdal, H. P., Lønning, P. E., Bee, V., Fung, H., Mackey, J., Martin, M., Press, M., Azambuja, E. D., Gelber, R., Regan, M., Leo, A. D., Dooren, V. V., Nogaret, J. M., Bartlett, J., Chen, B. E., Gelmon, K., Goss, P. E., Levine, M. N., Parulekar, W., Pritchard, K. I., Shepherd, L., Berry, D., Cirrincione, C., Shulman, L. N., Winer, E., Gelman, R. S., Harris, J. R., Henderson, C., Shapiro, C. L., Christiansen, P., Ewertz, M., Mouridsen, H. T., Leeuwen, E. V., Linn, S., Rossum, A. G. J. V., Tinteren, H. V., Werkhoven, E. V., Goldstein, L., Gray, R., Eiermann, W., Gianni, L., Valagussa, P., Bogaerts, J., Bonnefoi, H., Poncet, C., Huovinen, R., Joensuu, H., Bonneterre, J., Fargeot, P., Fumoleau, P., Kerbrat, P., Luporsi, E., Namer, M., Carrasco, E. M., Segui, M. A., Meisner, C., Loibl, S., Nekljudova, V., Thomssen, C., Minckwitz, G. V., Kümmel, S., Lopez, M., Vici, P., Fountzilas, G., Koliou, G., Mavroudis, D., Saloustros, E., Brain, E., Delaloge, S., Michiels, S., Mathoulin-Pelissier, S., Bines, J., Sarmento, R. M. B., Bonadonna, G., Brambilla, C., Rossi, A., Bliss, J., Coombes, R. C., Kilburn, L., Marty, M., Amadori, D., Boccardo, F., Nanni, O., Rubagotti, A., Scarpi, E., Masuda, N., Toi, M., Ueno, T., Ishikawa, T., Matsumoto, K., Takao, S., Sommer, H., Foroglou, P., Giokas, G., Kondylis, D., Lissaios, B., Reinisch, M., Lee, K. S., Nam, B., Ro, J. S., Matteis, A. D., Perrone, F., Tang, G., Wolmark, N., Hozumi, Y., Nomura, Y., Earl, H., Hiller, L., Vallier, A., Mastro, L. D., Venturini, M., Delozier, T., Lemonnier, J., Martin, A., Roché, H., Spielmann, M., Chen, X., Shen, K., Albain, K., Barlow, W., Budd, G. T., Gralow, J., Hayes, D., Bartlett-Lee, P., Ellis, P., Bianco, A. R., Laurentiis, M. D., Placido, S. D., Wildiers, H., Hsu, L., Eremin, O., Walker, L. G., Ahlgren, J., Blomqvist, C., Holmberg, L., Lindman, H., Asmar, L., Jones, S. E., Gluz, O., Liedtke, C., Arriagada, R., Bergsten-Nordström, E., Carey, L., Coleman, R., Cuzick, J., Davidson, N., Dignam, J., Dowsett, M., Francis, P. A., Goetz, M. P., Goodwin, P., Halpin-Murphy, P., Hill, C., Jagsi, R., Mukai, H., Ohashi, Y., Pierce, L., Poortmans, P., Raina, V., Rea, D., Robertson, J., Rutgers, E., Salgado, R., Spanic, T., Tutt, A., Viale, G., Wang, X., Whelan, T., Wilcken, N., Cameron, D., Bergh, J., & Swain, S. M. (2023). Anthracycline-containing and taxane-containing chemotherapy for early-stage operable breast cancer: a patient-level meta-analysis of 100 000 women from 86 randomised trials. The Lancet. https://doi.org/10.1016/s0140-6736(23)00285-4

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